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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

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⊟Summary[edit | edit source]

Contents

  • 1 Summary
  • 2 Genome View
  • 3 Gene
    • 3.1 General
    • 3.2 Accession numbers
    • 3.3 Phenotype
    • 3.4 DNA sequence
  • 4 Protein
    • 4.1 General
    • 4.2 Function
    • 4.3 Structure, modifications & cofactors
    • 4.4 Localization
    • 4.5 Accession numbers
    • 4.6 Protein sequence
    • 4.7 Experimental data
  • 5 Expression & Regulation
    • 5.1 Operon
    • 5.2 Regulation
    • 5.3 Expression data
  • 6 Biological Material
    • 6.1 Mutants
    • 6.2 Expression vector
    • 6.3 lacZ fusion
    • 6.4 GFP fusion
    • 6.5 two-hybrid system
    • 6.6 FLAG-tag construct
    • 6.7 Antibody
  • 7 Other Information
  • 8 Literature
    • 8.1 References
    • 8.2 Relevant publications
  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_2092 [new locus tag: SPH_RS10230 ]
  • pan locus tag?: PNEUPAN003521000
  • symbol: SPH_2092
  • pan gene symbol?: mshD_2
  • synonym:
  • product: acetyltransferase, gnat family

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_2092 [new locus tag: SPH_RS10230 ]
  • symbol: SPH_2092
  • product: acetyltransferase, gnat family
  • replicon: chromosome
  • strand: -
  • coordinates: 1927157..1927675
  • length: 519
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP000936 (1927157..1927675) NCBI
  • BioCyc: see SPH_RS10230
  • MicrobesOnline: 5696913 MicrobesOnline
  • PneumoBrowse for strain D39V: SPV_1742 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGGAGTATGAATTGCTCATTAGGGAAGCAGAGCCCAAAGATGCAGCTGAATTAGTGGCC
    TTTTTAAATCGTGTGAGTTTGGAGACAGACTTTACCAGCCTAGACGGAGATGGTATTCTC
    TTGACTAGTGAGGAGATGGAAATATTCCTCAACAAGCAAGCTAGTTCGGACAATCAGATA
    ACCTTACTTGCATTCTTAAATGGCAAAATTGCTGGTATTGTAAATATTACAGCTGACCAG
    CGTAAGAGAGTCCGTCATATTGGAGATCTCTTCATTGTGATTGGAAAAAGATATTGGAAT
    AATGGCTTGGGAAGTTTGTTGCTAGAAGAAGCGATAGAGTGGGCACAAGCAAGTGGCATT
    CTGCGTCGTCTCCAACTGACTGTCCAAACTCGTAATCAAGCAGCAGTCCATCTTTATCAA
    AAGCATGGCTTTGTCATTGAAGGTAGCCAAGAGCGTGGGGCATATATAGAAGAAGGGAAA
    TTTATCGATGTTTACTTGATGGGTAAACTGATAGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    519

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_2092 [new locus tag: SPH_RS10230 ]
  • symbol: SPH_2092
  • description: acetyltransferase, gnat family
  • length: 172
  • theoretical pI: 4.75677
  • theoretical MW: 19397
  • GRAVY: -0.069186

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase (TIGR03585; EC 2.3.1.202; HMM-score: 43.6)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal-protein-alanine acetyltransferase (TIGR01575; EC 2.3.1.128; HMM-score: 38.7)
    and 3 more
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides TDP-D-fucosamine acetyltransferase (TIGR02382; HMM-score: 25.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs mycothiol synthase (TIGR03448; EC 2.3.1.189; HMM-score: 23.2)
    GNAT-family acetyltransferase TIGR03103 (TIGR03103; HMM-score: 11.7)
  • TheSEED  :
    • Acetyltransferase (EC 2.3.1.-)
  • ⊞PFAM:
    Acetyltrans (CL0257) Acetyltransf_1; Acetyltransferase (GNAT) family (PF00583; HMM-score: 64.2)
    and 7 more
    Acetyltransf_10; Acetyltransferase (GNAT) domain (PF13673; HMM-score: 45.2)
    Acetyltransf_7; Acetyltransferase (GNAT) domain (PF13508; HMM-score: 42.1)
    Acetyltransf_3; Acetyltransferase (GNAT) domain (PF13302; HMM-score: 39.8)
    Acetyltransf_4; Acetyltransferase (GNAT) domain (PF13420; HMM-score: 31.4)
    Acetyltransf_8; Acetyltransferase (GNAT) domain (PF13523; HMM-score: 19.9)
    FR47; FR47-like protein (PF08445; HMM-score: 13.3)
    no clan defined GP46; Phage protein GP46 (PF07409; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002275
    • TAT(Tat/SPI): 0.000239
    • LIPO(Sec/SPII): 0.000276
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACA35790 NCBI
  • UniProt: B1I8Q4 UniProt

⊟Protein sequence[edit | edit source]

  • MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSEEMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNGLGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGKFIDVYLMGKLID

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

  • MicrobesOnline: SPH_2091 < SPH_2092 < SPH_2093

⊟Regulation[edit | edit source]

  • data available for D39, TIGR4

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V: SPV_1742 PneumoExpress

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPH_2092&oldid=13011"
  • This page was last edited on 20 January 2022, at 13:33.
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