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serotype 1
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NCTC7465
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TCH8431/19A
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Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 04-FEB-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV104
  • locus tag: INV104_17810 [new locus tag: INV104_RS10375 ]
  • pan locus tag?: PNEUPAN003700000
  • symbol: INV104_17810
  • pan gene symbol?: MATE
  • synonym:
  • product: multi antimicrobial extrusion (MATE) family transporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: INV104_17810 [new locus tag: INV104_RS10375 ]
  • symbol: INV104_17810
  • product: multi antimicrobial extrusion (MATE) family transporter
  • replicon: chromosome
  • strand: -
  • coordinates: 1949353..1950633
  • length: 1281
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGTTTAAGAAAAATAAAGACATTCTTAATATTGCATTGCCAGCTATGGGTGAAAACTTT
    TTGCAGATGCTAATGGGAATGGTGGACAGTTATTTGGTTGCTCATTTAGGATTGATAGCT
    ATTTCAGGGGTTTCAGTAGCTGGTAATATTATCACCATTTATCAGGCGATTTTCATCGCT
    CTGGGAGCTGCTATTTCCAGTGTTATTTCAAAAAGCATAGGGCAGAAAGACCAGTCGAAG
    TTGGCCTATCATGTGACTGAGGCGTTGAAGATTACCTTACTATTAAGTTTCCTTTTAGGA
    TTTTTGTCCATCTTCGCTGGGAAAGAGATGATAGGACTTTTGGGGACGGAGAGGGATGTA
    GCTGAGAGTGGTGGACTGTATCTATCTTTGGTAGGCGGATCGATTGTTCTCTTAGGTTTA
    ATGACTAGTTTGGGAGCCTTGATTCGTGCAACGCATAATCCACGTCTGCCTCTCTATGTT
    AGTTTTTTATCCAATGCCTTGAATATTCTTTTTTCAAGTCTAGCTATTTTTGTTCTGGAT
    ATGGGGATAGCTGGTGTTGCTTGGGGGACAATTCTGTCTCGTTTGGTTGGTCTTGTGATT
    TTGTGGTCACAATTAAAACTGCCTTATGGGAAGCTAACTTTTGGTTTAGATAAGGAACTG
    TTGACCTTGGCTTTACCAGCAGCTGGAGAGCGACTTATGATGAGGGCTGGAGATGTAGTG
    ATCATTGCCTTGGTCGTTTCTTTTGGGACGGAGGCAGTTGCTGGGAATGCAATCGGAGAA
    GTCTTGACCCAGTTTAACTATATGCCTGCCTTTGGTGTCGCTACGGCAACGGTCATGCTG
    TTGGCCCGAGCAGTTGGAGAGGATGATTGGAAAAGAGTTGCTAGTTTGAGTAAACAAACC
    TTTTGGCTTTCTCTGTTCCTCATGTTGCCCCTGTCCTTTAGTATATATGTCTTGGGTGTA
    CCATTAACTCATCTCTATACGACTGATTCTCTAGCGGTGGAGGCTAGTGTTCTAGTGACA
    CTGTTTTCACTACTTGGTACCCCTATGACGACAGGAACAGTCATCTATACGGCAGTCTGG
    CAGGGATTAGGAAATGCACGCCTCCCTTTTTATGCGACAAGTATAGGCATGTGGTGTATC
    CGCATTGGGACAGGATATCTGATGGGTATTGTGCTTGGTTGGGGCTTGCCTGGTATTTGG
    GCAGGGTCTCTCTTGGATAATGGTTTTCGCTGGTTATTTCTACGCTATCGTTACCAGCGC
    TATATGAGCTTGAAAGGATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1281

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: INV104_17810 [new locus tag: INV104_RS10375 ]
  • symbol: INV104_17810
  • description: multi antimicrobial extrusion (MATE) family transporter
  • length: 426
  • theoretical pI: 9.56577
  • theoretical MW: 45931.4
  • GRAVY: 0.790845

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Other MATE efflux family protein (TIGR00797; HMM-score: 199.2)
    and 1 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan murein biosynthesis integral membrane protein MurJ (TIGR01695; HMM-score: 49.8)
  • TheSEED  :
    • Multi antimicrobial extrusion (MATE) family transporter
  • ⊞PFAM:
    MviN_MATE (CL0222) MatE; MatE (PF01554; HMM-score: 162.5)
    and 2 more
    MurJ; Lipid II flippase MurJ (PF03023; HMM-score: 55.2)
    Polysacc_synt_C; Polysaccharide biosynthesis C-terminal domain (PF14667; HMM-score: 26.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 11
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9998
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.017493
    • TAT(Tat/SPI): 0.000198
    • LIPO(Sec/SPII): 0.002561
  • predicted transmembrane helices (TMHMM): 11

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW37462 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGVSVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFLSIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYVSFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDKELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATATVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVEASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVLGWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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