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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_2259 [new locus tag: SPH_RS11070 ]
  • pan locus tag?: PNEUPAN003754000
  • symbol: SPH_2259
  • pan gene symbol?: guaA_2
  • synonym:
  • product: glutamine amidotransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPH_2259 [new locus tag: SPH_RS11070 ]
  • symbol: SPH_2259
  • product: glutamine amidotransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 2064948..2065637
  • length: 690
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGCTAGAACGGTTGTAGGAGTTGCTGCAAATCTATGTCCCGTAGACGCAGAAGGCAAA
    ATCATTCATTCATCTGTATCTTGTAGATTCGCAGAGATCATTCGTCAAGTCGGTGGTCTC
    CCTTTAGTCATTCCTGTTGGTGATGAGTCAGTTGTACGTGATTATGTGGAAATGATTGAC
    AAACTCATTTTGACAGGAGGCCAAAATGTTCATCCTCAGTTTTATGGAGAGAAAAAGACC
    GTCGAAAGCGATGATTACAATCTGGTCCGTGACGAATTTGAATTGGCACTCTTGAAGGAA
    GCGCTTCGTCAGAATAAACCAATTATGGCAATCTGTCGCGGTGTCCAACTTGTCAATGTT
    GCCTTTGGTGGAACCCTCAATCAAGAAATCGAAGGTCACTGGCAAGGACTACCTTTCGGG
    ACATCTCACTCTATTGAGACAGTAGAAGGAAGCGTGGTGGCTAAGCTATTTGGGAAAGAA
    AGTCAGGTCAACTCAGTCCATCGTCAAAGCATTAAAGATTTGGCACCTAATTTCCGTGTA
    ACTGCTATTGATTCAAGAGACCAAACTATTGAAGCGATTGAGTCTATCGACGAGCACCGC
    ATTATCGGTTTACAGTGGCATCCAGAGTTTCTGGTTAATGAAGAAGATGGCAATTTAGAA
    TTATTTGAGTATTTATTGAATGAACTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    690

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPH_2259 [new locus tag: SPH_RS11070 ]
  • symbol: SPH_2259
  • description: glutamine amidotransferase
  • length: 229
  • theoretical pI: 4.56649
  • theoretical MW: 25491.8
  • GRAVY: -0.0973799

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis GMP synthase (glutamine-hydrolyzing), N-terminal domain (TIGR00888; EC 6.3.5.2; HMM-score: 44.9)
    and 6 more
    Metabolism Amino acid biosynthesis Aromatic amino acid family anthranilate synthase (TIGR01815; EC 4.1.3.27; HMM-score: 30.2)
    glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase (TIGR00566; HMM-score: 24.7)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis carbamoyl-phosphate synthase, small subunit (TIGR01368; EC 6.3.5.5; HMM-score: 24.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis CTP synthase (TIGR00337; EC 6.3.4.2; HMM-score: 18.8)
    Metabolism Amino acid biosynthesis Histidine family imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (TIGR01855; EC 2.4.2.-; HMM-score: 17)
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides intracellular protease, PfpI family (TIGR01382; HMM-score: 12)
  • TheSEED  :
    • Glutamine amidotransferase, class I
  • ⊞PFAM:
    Glutaminase_I (CL0014) Peptidase_C26; Peptidase C26 (PF07722; HMM-score: 227.3)
    and 3 more
    GATase; Glutamine amidotransferase class-I (PF00117; HMM-score: 60.5)
    DJ-1_PfpI; DJ-1/PfpI family (PF01965; HMM-score: 15.8)
    HemS_ChuX (CL0312) HemS; Haemin-degrading HemS.ChuX domain (PF05171; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.025911
    • TAT(Tat/SPI): 0.000621
    • LIPO(Sec/SPII): 0.004539
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVIPVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEALRQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKESQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGNLELFEYLLNEL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • ⊞regulator: CmbR* (activation (repression)) regulon

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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