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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-SEP-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • pan locus tag?: PNEUPAN003114000
  • symbol: frp
  • pan gene symbol?: frp
  • synonym:
  • product: NADPH-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • symbol: frp
  • product: NADPH-dependent oxidoreductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1636230..1636943
  • length: 714
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACAGAAACCATTAAATTGATGAAGGCTCATACTTCAGTGCGCAGGTTTAAAGAGCAA
    GAAATTCCCCAAGTAGACTTAAATGAGATTTTGACAGCAGCCCAGATGGCATCATCTTGG
    AAGAATTTCCAATCCTACTCTGTGATTGTGGTACGAAGTCAAGAGAAGAAAGATGCCTTG
    TATGAATTGGTACCTCAAGAAGCCATTCGCCAGTCTGCTGTTTTCCTTCTCTTTGTCGGA
    GATTTGAACCGAGCAGAAAAGGGAGCCCGACTTCATACCGACACCTTCCAACCCCAAGGT
    GTGGAAGGTCTCTTGATTAGTTCGGTCGATGCAGCTCTTGCTGGACAAAACGCCTTGTTG
    GCAGCTGAAAGCTTGGGCTATGGTGGTGTGATTATCGGTTTGGTTCGATACAAGTCTGAA
    GAAGTGGCAGAGCTCTTTAACTTACCTGACTACACCTATTCTGTCTTTGGGATGGCACTG
    GGTGTGCCAAATCAACATCATGATATGAAACCGAGACTGCCACTAGAGAATGTTGTCTTT
    GAGGAAGAATACCAAGAACAGTCAACTGAGGCAATCCAAGCTTATGACCGTGTTCAGGCT
    GACTATGCTGGGGCGCGTGCGACCACAAGCTGGAGTCAGCGCCTAGCAGAACAGTTTGGT
    CAAGCTGAACCAAGCTCAACTAGAAAAAATCTTGAACAGAAGAAATTGTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    714

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • symbol: Frp
  • description: NADPH-dependent oxidoreductase
  • length: 237
  • theoretical pI: 5.00552
  • theoretical MW: 26543.8
  • GRAVY: -0.331646

⊟Function[edit | edit source]

  • ⊞⊞TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin 5,6-dimethylbenzimidazole synthase (TIGR02476; EC 1.14.99.40; HMM-score: 35)
    and 3 more
    SagB-type dehydrogenase domain (TIGR03605; HMM-score: 14.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other F420 biosynthesis protein FbiB, C-terminal domain (TIGR03553; HMM-score: 12.7)
    Metabolism Energy metabolism Methanogenesis putative methanogenesis marker 16 metalloprotein (TIGR03287; HMM-score: 9.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞⊞PFAM:
    FMN-dep-NRtase (CL0529) Nitroreductase; Nitroreductase family (PF00881; HMM-score: 75.9)
    and 1 more
    TM1586_NiRdase; Putative TM nitroreductase (PF14512; HMM-score: 19)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001879
    • TAT(Tat/SPI): 0.000431
    • LIPO(Sec/SPII): 0.000368
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG82172 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQSYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMALGVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQAEPSSTRKNLEQKKLL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=ASP0581_16500&oldid=48347"
Insert paragraph

NCBI: 03-SEP-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • pan locus tag?: PNEUPAN003114000
  • symbol: frp
  • pan gene symbol?: frp
  • synonym:
  • product: NADPH-dependent oxidoreductase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • symbol: frp
  • product: NADPH-dependent oxidoreductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1636230..1636943
  • length: 714
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACAGAAACCATTAAATTGATGAAGGCTCATACTTCAGTGCGCAGGTTTAAAGAGCAA
    GAAATTCCCCAAGTAGACTTAAATGAGATTTTGACAGCAGCCCAGATGGCATCATCTTGG
    AAGAATTTCCAATCCTACTCTGTGATTGTGGTACGAAGTCAAGAGAAGAAAGATGCCTTG
    TATGAATTGGTACCTCAAGAAGCCATTCGCCAGTCTGCTGTTTTCCTTCTCTTTGTCGGA
    GATTTGAACCGAGCAGAAAAGGGAGCCCGACTTCATACCGACACCTTCCAACCCCAAGGT
    GTGGAAGGTCTCTTGATTAGTTCGGTCGATGCAGCTCTTGCTGGACAAAACGCCTTGTTG
    GCAGCTGAAAGCTTGGGCTATGGTGGTGTGATTATCGGTTTGGTTCGATACAAGTCTGAA
    GAAGTGGCAGAGCTCTTTAACTTACCTGACTACACCTATTCTGTCTTTGGGATGGCACTG
    GGTGTGCCAAATCAACATCATGATATGAAACCGAGACTGCCACTAGAGAATGTTGTCTTT
    GAGGAAGAATACCAAGAACAGTCAACTGAGGCAATCCAAGCTTATGACCGTGTTCAGGCT
    GACTATGCTGGGGCGCGTGCGACCACAAGCTGGAGTCAGCGCCTAGCAGAACAGTTTGGT
    CAAGCTGAACCAAGCTCAACTAGAAAAAATCTTGAACAGAAGAAATTGTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    714

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ASP0581_16500 [new locus tag: EL334_RS08730 ]
  • symbol: Frp
  • description: NADPH-dependent oxidoreductase
  • length: 237
  • theoretical pI: 5.00552
  • theoretical MW: 26543.8
  • GRAVY: -0.331646

Insert paragraph

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin 5,6-dimethylbenzimidazole synthase (TIGR02476; EC 1.14.99.40; HMM-score: 35)
    and 3 more
    SagB-type dehydrogenase domain (TIGR03605; HMM-score: 14.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other F420 biosynthesis protein FbiB, C-terminal domain (TIGR03553; HMM-score: 12.7)
    Metabolism Energy metabolism Methanogenesis putative methanogenesis marker 16 metalloprotein (TIGR03287; HMM-score: 9.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞PFAM:
    FMN-dep-NRtase (CL0529) Nitroreductase; Nitroreductase family (PF00881; HMM-score: 75.9)
    and 1 more
    TM1586_NiRdase; Putative TM nitroreductase (PF14512; HMM-score: 19)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001879
    • TAT(Tat/SPI): 0.000431
    • LIPO(Sec/SPII): 0.000368
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG82172 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQSYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVEGLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMALGVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQFGQAEPSSTRKNLEQKKLL

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

  • regulator:

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph