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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • pan locus tag?: PNEUPAN003915000
  • symbol: SPAP_2246
  • pan gene symbol?: dnaC
  • synonym: dnaB
  • product: Replicative DNA helicase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • symbol: SPAP_2246
  • product: Replicative DNA helicase
  • replicon: chromosome
  • strand: -
  • coordinates: 2091600..2092952
  • length: 1353
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCAGAAGTAGAAGAGTTACGAGTACAACCTCAAGATATCTTAGCTGAGCAATCCGTT
    TTAGGGGCTATCTTTATTGATGAGAGTAAACTTGTTTTTGTGCGAGAATACATTGAGTCT
    CGGGACTTTTTTAAGTATGCCCATCGTTTGATTTTCCAAGCCATGGTCGATTTATCCGAT
    CGTGGTGATGCCATAGATGCAACAACGGTTCGTACTATCCTTGATAATCAAGGTGATTTA
    CAGAATATTGGTGGCTTGTCTTACTTGGTTGAGATTGTCAATTCTGTGCCAACTTCTGCT
    AATGCGGAGTATTATGCTAAGATTGTTGCAGAAAAAGCAATGCTACGTCGTTTAATTGCC
    AAGTTGACAGAGTCTGTCAACCAAGCTTACGAAGCGTCACAACCAGCTGATGAAATTATT
    GCTCAGGCAGAAAAAGGGCTGATTGATGTCAGTGAAAATGCAAATCGAAGCGGGTTTAAG
    AACATTCGAGATGTGTTGAATCTCAACTTTGGAAATCTGGAAGCTCGCTCGCAACAAACG
    ACCGATATTACAGGTATTGCGACAGGTTATCGTGATTTGGATCATATGACAACAGGACTT
    CATGAGGAGGAGTTGATTATCTTAGCAGCTCGTCCAGCAGTTGGTAAGACAGCATTTGCC
    TTGAATATCGCTCAGAACATTGGGACTAAGTTGGACAAAACGGTTGCTATTTTTTCACTC
    GAAATGGGTGCGGAAAGCTTGGTAGATCGTATGTTAGCTGCAGAAGGCTTAGTGGAGTCA
    CATTCTATCCGTACAGGGCAATTGACAGATGAGGAGTGGCAAAAATATACTATTGCTCAG
    GGTAATCTAGCTAACGCCAGTATCTATATCGATGATACGCCAGGTATTCGGATTACAGAG
    ATTCGTTCTCGTTCTCGTAAATTGGCTCAAGAAACTGGAAATCTTGGTTTGATTTTGATA
    GACTATTTGCAACTTATCACGGGAACTGGTCGAGAAAATCGTCAACAAGAAGTTTCTGAA
    ATTTCTCGTCAGTTGAAAATACTAGCCAAGGAATTGAAGGTTCCAGTAATCGCTCTGAGT
    CAGCTTTCTCGTGGTGTAGAACAACGTCAGGACAAGAGACCGGTCTTGTCTGATATTCGT
    GAATCTGGGTCTATTGAGCAGGACGCTGATATCGTAGCTTTTCTCTATCGCGATGACTAC
    TATGAACGTGGTGGTGAAGAAGAGGAAGGTATCCCAAATAATAAGGTGGAAGTTATTATC
    GAGAAAAACCGTAGTGGAGCTCGTGGAACAGTGGAATTGATTTTCCAAAAAGAATACAAT
    AAATTTTCAAGTATCTCAAAGAGGGAGGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1353

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • symbol: SPAP_2246
  • description: Replicative DNA helicase
  • length: 450
  • theoretical pI: 4.60373
  • theoretical MW: 50203.3
  • GRAVY: -0.307111

⊟Function[edit | edit source]

  • ⊞⊞TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair replicative DNA helicase (TIGR00665; EC 3.6.4.12; HMM-score: 553.9)
    and 1 more
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage replicative helicase, DnaB family (TIGR03600; HMM-score: 431.4)
  • TheSEED  :
    • Replicative DNA helicase DnaB (=BsDnaC) (EC 3.6.4.12)
    DNA Metabolism DNA replication DNA-replication  Replicative DNA helicase (EC 3.6.1.-)
  • ⊞⊞PFAM:
    P-loop_NTPase (CL0023) DnaB_C; DnaB-like helicase C terminal domain (PF03796; HMM-score: 364.7)
    and 4 more
    no clan defined DnaB; DnaB-like helicase N terminal domain (PF00772; HMM-score: 108.6)
    P-loop_NTPase (CL0023) AAA_25; AAA domain (PF13481; HMM-score: 45.3)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 17.7)
    ATPase; KaiC (PF06745; HMM-score: 15.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000746
    • TAT(Tat/SPI): 0.000305
    • LIPO(Sec/SPII): 0.000108
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85777 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFKNIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPAP_2246&oldid=44436"
Insert paragraph

NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • pan locus tag?: PNEUPAN003915000
  • symbol: SPAP_2246
  • pan gene symbol?: dnaC
  • synonym: dnaB
  • product: Replicative DNA helicase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • symbol: SPAP_2246
  • product: Replicative DNA helicase
  • replicon: chromosome
  • strand: -
  • coordinates: 2091600..2092952
  • length: 1353
  • essential: unknown other strains

Insert paragraph

⊟Accession numbers[edit | edit source]

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGCAGAAGTAGAAGAGTTACGAGTACAACCTCAAGATATCTTAGCTGAGCAATCCGTT
    TTAGGGGCTATCTTTATTGATGAGAGTAAACTTGTTTTTGTGCGAGAATACATTGAGTCT
    CGGGACTTTTTTAAGTATGCCCATCGTTTGATTTTCCAAGCCATGGTCGATTTATCCGAT
    CGTGGTGATGCCATAGATGCAACAACGGTTCGTACTATCCTTGATAATCAAGGTGATTTA
    CAGAATATTGGTGGCTTGTCTTACTTGGTTGAGATTGTCAATTCTGTGCCAACTTCTGCT
    AATGCGGAGTATTATGCTAAGATTGTTGCAGAAAAAGCAATGCTACGTCGTTTAATTGCC
    AAGTTGACAGAGTCTGTCAACCAAGCTTACGAAGCGTCACAACCAGCTGATGAAATTATT
    GCTCAGGCAGAAAAAGGGCTGATTGATGTCAGTGAAAATGCAAATCGAAGCGGGTTTAAG
    AACATTCGAGATGTGTTGAATCTCAACTTTGGAAATCTGGAAGCTCGCTCGCAACAAACG
    ACCGATATTACAGGTATTGCGACAGGTTATCGTGATTTGGATCATATGACAACAGGACTT
    CATGAGGAGGAGTTGATTATCTTAGCAGCTCGTCCAGCAGTTGGTAAGACAGCATTTGCC
    TTGAATATCGCTCAGAACATTGGGACTAAGTTGGACAAAACGGTTGCTATTTTTTCACTC
    GAAATGGGTGCGGAAAGCTTGGTAGATCGTATGTTAGCTGCAGAAGGCTTAGTGGAGTCA
    CATTCTATCCGTACAGGGCAATTGACAGATGAGGAGTGGCAAAAATATACTATTGCTCAG
    GGTAATCTAGCTAACGCCAGTATCTATATCGATGATACGCCAGGTATTCGGATTACAGAG
    ATTCGTTCTCGTTCTCGTAAATTGGCTCAAGAAACTGGAAATCTTGGTTTGATTTTGATA
    GACTATTTGCAACTTATCACGGGAACTGGTCGAGAAAATCGTCAACAAGAAGTTTCTGAA
    ATTTCTCGTCAGTTGAAAATACTAGCCAAGGAATTGAAGGTTCCAGTAATCGCTCTGAGT
    CAGCTTTCTCGTGGTGTAGAACAACGTCAGGACAAGAGACCGGTCTTGTCTGATATTCGT
    GAATCTGGGTCTATTGAGCAGGACGCTGATATCGTAGCTTTTCTCTATCGCGATGACTAC
    TATGAACGTGGTGGTGAAGAAGAGGAAGGTATCCCAAATAATAAGGTGGAAGTTATTATC
    GAGAAAAACCGTAGTGGAGCTCGTGGAACAGTGGAATTGATTTTCCAAAAAGAATACAAT
    AAATTTTCAAGTATCTCAAAGAGGGAGGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1353

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_2246 [new locus tag: SPAP_RS11105 ]
  • symbol: SPAP_2246
  • description: Replicative DNA helicase
  • length: 450
  • theoretical pI: 4.60373
  • theoretical MW: 50203.3
  • GRAVY: -0.307111

Insert paragraph

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair replicative DNA helicase (TIGR00665; EC 3.6.4.12; HMM-score: 553.9)
    and 1 more
    Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage replicative helicase, DnaB family (TIGR03600; HMM-score: 431.4)
  • TheSEED  :
    • Replicative DNA helicase DnaB (=BsDnaC) (EC 3.6.4.12)
    DNA Metabolism DNA replication DNA-replication  Replicative DNA helicase (EC 3.6.1.-)
  • ⊞PFAM:
    P-loop_NTPase (CL0023) DnaB_C; DnaB-like helicase C terminal domain (PF03796; HMM-score: 364.7)
    and 4 more
    no clan defined DnaB; DnaB-like helicase N terminal domain (PF00772; HMM-score: 108.6)
    P-loop_NTPase (CL0023) AAA_25; AAA domain (PF13481; HMM-score: 45.3)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 17.7)
    ATPase; KaiC (PF06745; HMM-score: 15.1)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000746
    • TAT(Tat/SPI): 0.000305
    • LIPO(Sec/SPII): 0.000108
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85777 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFFKYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANAEYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFKNIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTAFALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKYTIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENRQQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

  • regulator:

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph