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serotype 4
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serotype 2
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serotype 19A
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serotype 6B
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Hu17
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INV200
serotype 14
JJA
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MDRSPN001
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NCTC7465
serotype 1
NCTC7466
serotype 2
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serotype 1
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SP49
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SPN032672
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SPN034156
serotype 3
SPN034183
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SPN994038
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SPN994039
serotype 3
SPNA45
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ST556
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TCH8431/19A
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Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae P1031
  • locus tag: SPP_1104 [new locus tag: SPP_RS05470 ]
  • pan locus tag?: PNEUPAN002239000
  • symbol: SPP_1104
  • pan gene symbol?: rluD3
  • synonym:
  • product: ribosomal large subunit pseudouridine synthase, RluD subfamily

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPP_1104 [new locus tag: SPP_RS05470 ]
  • symbol: SPP_1104
  • product: ribosomal large subunit pseudouridine synthase, RluD subfamily
  • replicon: chromosome
  • strand: +
  • coordinates: 1010924..1011820
  • length: 897
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAGGTTTGAATTTATCGCAGATGAACATGTCAAGGTTAAGACCTTTTTAAAAAAGCAC
    GAGGTTTCTAAGGGATTGCTGGCTAAGATTAAGTTTCGAGGTGGAGCTATTCTGGTCAAT
    AATCAACCGCAAAATGCAACGTATCTATTGGACGTTGGAGACTACGTTACCATTTACATT
    CCCGCTGAGGAAGGCTTTGAAACCTTGGAGGCTATTGAGCATCCATTAGATATTCTCTAT
    GAGGATGACCACTTTCTAGTCTTGAATAAACCCTATGGAGTGGCTTCTATTCCTAGTGTC
    AATCACTCTAACACCATTGCCAATTTTATCAAGGGTTACTATGTCAAGCAAAATTATGAA
    AATCAGCAGGTTCACATTGTTACCAGACTAGATAGGGACACTTCTGGCTTGATGCTCTTT
    GCCAAGCACGGTTATGCCCATGCACGATTAGACAAGCAGTTGCAGAAGAAATCTATCGAG
    AAACGCTACTTTGCTTTGGTTAAGGGAGATGGACATTTGGAGCCAGAAGGGGAAATTATT
    GCTCCGATTGCGCGTGATGAAGATTCCATTATTACCAGACGAGTGGCTAAAGGCGGAAAG
    TATGCCCATACTTCATACAAGATTGTAGCTTCTTATGGAAATATTCACTTGGTCTATATT
    CACCTGCACACTGGTCGAACCCATCAAATCCGAGTCCATTTTTCTCATATCGGTTTTCCT
    TTGCTGGGAGATGATTTGTATGGTGGTAGTCTGGAAGATGGTATTCAACGTCAGGCTCTG
    CATTGCCATTACCTATCCTTTTATCATCCATTTTTAGAGCAAGACTTGCAGTTAGAAAGT
    CCCTTGCCGGATGATTTCAGTAACCTTATTACCCAGTTATCAACTAATACTCTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    897

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPP_1104 [new locus tag: SPP_RS05470 ]
  • symbol: SPP_1104
  • description: ribosomal large subunit pseudouridine synthase, RluD subfamily
  • length: 298
  • theoretical pI: 6.94468
  • theoretical MW: 33966.4
  • GRAVY: -0.300671

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 240.3)
    and 3 more
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 90)
    Genetic information processing Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 39.4)
    Metabolism Energy metabolism TCA cycle isocitrate dehydrogenase, NADP-dependent (TIGR00127; EC 1.1.1.42; HMM-score: 10)
  • TheSEED  :
    • Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type
    Protein Metabolism Protein biosynthesis Ribosome biogenesis bacterial  Similar to ribosomal large subunit pseudouridine synthase D, Bacillus subtilis YjbO type
  • ⊞PFAM:
    PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 113.7)
    and 1 more
    S4 (CL0492) S4_2; S4 domain (PF13275; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002661
    • TAT(Tat/SPI): 0.000447
    • LIPO(Sec/SPII): 0.000478
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACO20228 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQNATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNHSNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIEKRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLVYIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDLQLESPLPDDFSNLITQLSTNTL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • ⊞regulator: CcpA regulon

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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