From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0191 [new locus tag: SPH_RS00915 ]
  • symbol: SPH_0191
  • product: ABC transporter membrane-spanning permease - sugar transport
  • replicon: chromosome
  • strand: +
  • coordinates: 165495..166454
  • length: 960
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGATATCAAAATAAAAAGGGAGGAAATTATGAAAAAGTTTTCAAAAACATTGAGAGAC
    AACTGGATCTTTCTCTTGATGGTTTTGCCAGGGGCACTCTGGTTGATTCTATTCTTTTAC
    ATTCCAGTATTTGGGAACGTGGTTGCCTTCAAAGACTACCACATGACCAGTAATGGTTTC
    ATAGATAGTATCATAAATAGTAAATGGGTCGGACTCGATAATTTTAGATTCTTATTTAGT
    TCAAGAGACGCCTTTATTATCACACGAAATACTGTCCTCTACAATCTTGGCTTTATCTTT
    CTAGGTTTAGTTGTATCTGTAGGGATTGCCATTATCCTCAGCGAGCTCCGTTCTAAGAGA
    ATGGTGAAGATTTTTCAAACTTCTATGTTGTTCCCTTACTTCTTGTCTTGGGTTATCATC
    AGTTTCTTTACAGATGCCTTCCTAAATATTGATAAAGGGGTGTTCAATCATCTATTGGAA
    AGTCTTGGTCTCAAAGAAGTCAATTTCTACGCTGACCTGGGCATCTGGCCCTATCTCCTA
    CTTTTCCTAGGTATTTGGAAAGGCTTTGGATATAGCAGTGTCATGTACTATGCGACGATC
    ATGGGAATTGATCCAACCTACTACGAAGCAGCGACAGTGGACGGAGCTAGCAAGTGGCAA
    CGTATTCGCAACGTAACCATTCCTCAGTTGACTCCGCTTGTAACTGTATTGACCATCCTT
    GCAGTCGGAAATATCTTCCGCGCAGACTTCGGTCTCTTCTATCAAATCCCACACAATGCT
    GGTCAGCTTTACAATGTAACCAACGTTTTGGACGTATATGTTTTTAATGGTTTGACTCAG
    ACAGCAGATATCGGTATGGCTGCAGCAGCCGGTCTTTACCAATCCGTTGTTGGTTTGATT
    CTGGTTATCCTATCAAACTTGCTTGCAAGACGAGTCGATCCAAACTCAGCTTTGTTCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_0191 [new locus tag: SPH_RS00915 ]
  • symbol: SPH_0191
  • description: ABC transporter membrane-spanning permease - sugar transport
  • length: 319
  • theoretical pI: 9.42195
  • theoretical MW: 36234.4
  • GRAVY: 0.605956

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 24.6)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 23.2)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 23.2)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 22.4)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 20.9)
    and 5 more
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 18.8)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 18.7)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 17.3)
    2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 16.4)
    2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 14.5)
  • TheSEED  :
    • Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
    Carbohydrates Di- and oligosaccharides Fructooligosaccharides(FOS) and Raffinose Utilization  Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 51.7)
    and 1 more
    no clan defined ATP1G1_PLM_MAT8; ATP1G1/PLM/MAT8 family (PF02038; HMM-score: 11.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006968
    • TAT(Tat/SPI): 0.000306
    • LIPO(Sec/SPII): 0.001966
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDIKIKREEIMKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Hungary19A-6
  • locus tag: SPH_0191 [new locus tag: SPH_RS00915 ]
  • pan locus tag?: PNEUPAN000721000
  • symbol: SPH_0191
  • pan gene symbol?: ABC-MSP_1
  • synonym:
  • product: ABC transporter membrane-spanning permease - sugar transport

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPH_0191 [new locus tag: SPH_RS00915 ]
  • symbol: SPH_0191
  • product: ABC transporter membrane-spanning permease - sugar transport
  • replicon: chromosome
  • strand: +
  • coordinates: 165495..166454
  • length: 960
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGATATCAAAATAAAAAGGGAGGAAATTATGAAAAAGTTTTCAAAAACATTGAGAGAC
    AACTGGATCTTTCTCTTGATGGTTTTGCCAGGGGCACTCTGGTTGATTCTATTCTTTTAC
    ATTCCAGTATTTGGGAACGTGGTTGCCTTCAAAGACTACCACATGACCAGTAATGGTTTC
    ATAGATAGTATCATAAATAGTAAATGGGTCGGACTCGATAATTTTAGATTCTTATTTAGT
    TCAAGAGACGCCTTTATTATCACACGAAATACTGTCCTCTACAATCTTGGCTTTATCTTT
    CTAGGTTTAGTTGTATCTGTAGGGATTGCCATTATCCTCAGCGAGCTCCGTTCTAAGAGA
    ATGGTGAAGATTTTTCAAACTTCTATGTTGTTCCCTTACTTCTTGTCTTGGGTTATCATC
    AGTTTCTTTACAGATGCCTTCCTAAATATTGATAAAGGGGTGTTCAATCATCTATTGGAA
    AGTCTTGGTCTCAAAGAAGTCAATTTCTACGCTGACCTGGGCATCTGGCCCTATCTCCTA
    CTTTTCCTAGGTATTTGGAAAGGCTTTGGATATAGCAGTGTCATGTACTATGCGACGATC
    ATGGGAATTGATCCAACCTACTACGAAGCAGCGACAGTGGACGGAGCTAGCAAGTGGCAA
    CGTATTCGCAACGTAACCATTCCTCAGTTGACTCCGCTTGTAACTGTATTGACCATCCTT
    GCAGTCGGAAATATCTTCCGCGCAGACTTCGGTCTCTTCTATCAAATCCCACACAATGCT
    GGTCAGCTTTACAATGTAACCAACGTTTTGGACGTATATGTTTTTAATGGTTTGACTCAG
    ACAGCAGATATCGGTATGGCTGCAGCAGCCGGTCTTTACCAATCCGTTGTTGGTTTGATT
    CTGGTTATCCTATCAAACTTGCTTGCAAGACGAGTCGATCCAAACTCAGCTTTGTTCTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPH_0191 [new locus tag: SPH_RS00915 ]
  • symbol: SPH_0191
  • description: ABC transporter membrane-spanning permease - sugar transport
  • length: 319
  • theoretical pI: 9.42195
  • theoretical MW: 36234.4
  • GRAVY: 0.605956

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein (TIGR00969; HMM-score: 24.6)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, permease protein CysT (TIGR02139; HMM-score: 23.2)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, permease protein (TIGR03262; HMM-score: 23.2)
    NifC-like ABC-type porter (TIGR01581; HMM-score: 22.4)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstC (TIGR02138; HMM-score: 20.9)
    and 5 more
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, permease protein PstA (TIGR00974; HMM-score: 18.8)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, permease protein (TIGR02141; HMM-score: 18.7)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, permease protein PhnE (TIGR01097; HMM-score: 17.3)
    2-aminoethylphosphonate ABC transporter, permease protein (TIGR03226; HMM-score: 16.4)
    2-aminoethylphosphonate ABC transport system, membrane component PhnV (TIGR03255; HMM-score: 14.5)
  • TheSEED  :
    • Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
    Carbohydrates Di- and oligosaccharides Fructooligosaccharides(FOS) and Raffinose Utilization  Multiple sugar ABC transporter, membrane-spanning permease protein MsmF
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 51.7)
    and 1 more
    no clan defined ATP1G1_PLM_MAT8; ATP1G1/PLM/MAT8 family (PF02038; HMM-score: 11.6)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9999
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.006968
    • TAT(Tat/SPI): 0.000306
    • LIPO(Sec/SPII): 0.001966
  • predicted transmembrane helices (TMHMM): 6

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MDIKIKREEIMKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator: CcpA regulon

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]