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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 22-NOV-2024

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⊟Summary[edit | edit source]

Contents

  • 1 Summary
  • 2 Genome View
  • 3 Gene
    • 3.1 General
    • 3.2 Accession numbers
    • 3.3 Phenotype
    • 3.4 DNA sequence
  • 4 Protein
    • 4.1 General
    • 4.2 Function
    • 4.3 Structure, modifications & cofactors
    • 4.4 Localization
    • 4.5 Accession numbers
    • 4.6 Protein sequence
    • 4.7 Experimental data
  • 5 Expression & Regulation
    • 5.1 Operon
    • 5.2 Regulation
    • 5.3 Expression data
  • 6 Biological Material
    • 6.1 Mutants
    • 6.2 Expression vector
    • 6.3 lacZ fusion
    • 6.4 GFP fusion
    • 6.5 two-hybrid system
    • 6.6 FLAG-tag construct
    • 6.7 Antibody
  • 7 Other Information
  • 8 Literature
    • 8.1 References
    • 8.2 Relevant publications
  • organism: Streptococcus pneumoniae gamPNI0373
  • locus tag: HMPREF1038_RS08535 [old locus tag: HMPREF1038_01739 ]
  • pan locus tag?: PNEUPAN003251000
  • symbol: HMPREF1038_RS08535
  • pan gene symbol?: Pn-aqpA
  • synonym:
  • product: MIP/aquaporin family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF1038_RS08535 [old locus tag: HMPREF1038_01739 ]
  • symbol: HMPREF1038_RS08535
  • product: MIP/aquaporin family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1602881..1603549
  • length: 669
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_018630 (1602881..1603549) NCBI
  • BioCyc: HMPREF1038_RS08535 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1569 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAAAAAATTTGTTGCTGAGTTAATCGGTACGTTCATGCTTGTGTTCGTTGGGACAGGA
    GCTGTTGTTTTTGGAAATGGTCTTGATGGCCTTGGTCACCTTGGAATCGCCTTTGCCTTT
    GGTTTGGCAATCGTGGTGGCAGCCTACTCAATCGGAACTGTTTCAGGTGCTCACTTGAAC
    CCGGCTGTTTCGATTGCTATGTTTGTAAACAAACGTTTGTCATCTTCAGAACTTGTAAAC
    TACATCCTTGGTCAGGTTGTTGGAGCTTTCATCGCTTCTGGCGCAGTCTTCTTCCTCTTG
    GGTAATTCAGGTATGTCAACTGCTAGCCTTGGTGAAAATGCCTTGGCAAACGGTGTCACT
    GTCTTTGGTGGTTTCTTGTTTGAAGTCATCGCAACTTTCTTGTTTGTCTTGGTTATCATG
    ACTGTGACTTCAGAAAGTAAGGGCAATGGCGCGATTGCTGGTTTGGTAATCGGTTTGTCA
    TTGATGGCGATGATTCTTGTCGGATTGAAGATTACTGGACTTTCAGTAAACCCAGCTCGT
    AGCTTGGCACCAGCTGTCTTGGTAGGCGGCGCAGCCCTTCAACAAGTTTGGATTTTCATC
    CTTGCACCAATCGCTGGTGGAGTTCTTGCAGCCCTTGTTGCAAAAAATTTCCTTGGAACA
    GAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    669

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF1038_RS08535 [old locus tag: HMPREF1038_01739 ]
  • symbol: HMPREF1038_RS08535
  • description: MIP/aquaporin family protein
  • length: 222
  • theoretical pI: 7.69256
  • theoretical MW: 22438.5
  • GRAVY: 1.19324

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Transport and binding proteins Unknown substrate MIP family channel proteins (TIGR00861; HMM-score: 164.7)
    and 1 more
    Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthetic protein FlhB (TIGR00328; HMM-score: 12)
  • TheSEED: see HMPREF1038_01739
  • ⊞PFAM:
    Aquaporin-like (CL0716) MIP; Major intrinsic protein (PF00230; HMM-score: 159)
    and 1 more
    no clan defined BTP; Chlorhexidine efflux transporter (PF05232; HMM-score: 6.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • ⊞DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0008
    • Cytoplasmic Membrane Score: 0.9804
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.0177
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.082793
    • TAT(Tat/SPI): 0.001246
    • LIPO(Sec/SPII): 0.042181
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000714849 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAIVVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGNSGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLSLMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFLGTEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V: SPV_1569 PneumoExpress

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=HMPREF1038_RS08535&oldid=76802"
  • This page was last edited on 20 January 2022, at 16:00.
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