⊟Summary[edit | edit source]

PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 05-OCT-2017

⊟Summary

• organism: Streptococcus pneumoniae MDRSPN001
locus tag: MDRSPN_01439 [new locus tag: MDRSPN_RS07545 ]
pan locus tag^?: PNEUPAN001538000
symbol: MDRSPN_01439
pan gene symbol^?: glnQ2
• synonym:
• product: arginine ABC transporter ATP-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: MDRSPN_01439 [new locus tag: MDRSPN_RS07545 ]
• symbol: MDRSPN_01439
• product: arginine ABC transporter ATP-binding protein
• replicon: chromosome
• strand: +
• coordinates: 1465912..1466670
• length: 759
• essential: unknown

⊟Accession numbers

• Location: AP018391 (1465912..1466670) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0531 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
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  301
  361
  421
  481
  541
  601
  661
  721
  
  ATGGCTTTAGTAGAATTTAAAAACGTCGAAAAATATTACGGAGACTACCACGCACTCCGC
  AACATCAATCTCCGTTTTGAAAAAGGACAAGTTGTTGTCCTGCTTGGACCTTCTGGCTCT
  GGGAAGTCCACTCTTATCCGTACGATCAATGGTTTAGAGGCTGTTGACAAAGGAAGTCTC
  CTAGTCAATGGGCACCAAGTTGCTGGTGCCAGCCAGAAAGATTTGGTACCTCTTCGCAAG
  GAAGTCGGCATGGTTTTTCAACATTTTAACCTTTATACACACAAAACTGTGTTAGAAAAC
  GTGACACTTGCGCCCGTTAAAGTTCTAGGAATTGATAAAAAAGAAGCTGAAAAAACCGCC
  CAAAAATATCTGGAATTTGTAAATATGTGGGACAAGAAAGATTCCTATCCCGCCATGCTA
  TCTGGTGGACAAAAACAGCGGATCGCCATCGCTCGTGGTCTTGCTATGCATCCGGAACTC
  CTCCTCTTTGATGAACCAACATCTGCTCTTGATCCTGAGACTATCGGAGATGTTCTAGCA
  GTTATGCAGAAACTGGCGCATGATGGGATGAACATGATCATCGTTACCCACGAAATGGGC
  TTTGCTCGAGAGGTTGCGGACCGCATTATCTTTATGGCCGACGGAGAAGTGTTAGTAGAT
  ACGACAGATGTCGATAACTTTTTTGACAATCCAAGCGAACCTCGTGCCCAACAATTCCTC
  AGCAAAATTATCAACCACGAAAGTGACAAAGTCAAATAA
  60
  120
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  240
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  360
  420
  480
  540
  600
  660
  720
  759
  

⊟Protein

⊟General

• locus tag: MDRSPN_01439 [new locus tag: MDRSPN_RS07545 ]
• symbol: MDRSPN_01439
• description: arginine ABC transporter ATP-binding protein
• length: 252
• theoretical pI: 6.31552
• theoretical MW: 28096.2
• GRAVY: -0.177778

⊟Function

• ⊞⊞TIGRFAM:
  ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 279.3)
  Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 235)
  and 80 more
  D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 205.2)
  Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 200.2)
  Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 199.3)
  Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 197.6)
  ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 197.5)
  Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 186.2)
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 184.8)
  Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 184.5)
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 177.5)
  Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 169.1)
  Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 169.1)
  Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 162.5)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 160.9)
  Metabolism Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 158.2)
  Metabolism Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 157.6)
  2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 145.6)
  Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 145.4)
  Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 144.4)
  thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 139.6)
  Metabolism Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 138.4)
  Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 138.3)
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 136.7)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 135.9)
  Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 128.8)
  Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 128.8)
  Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 126.1)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 126.1)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 125.9)
  Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 125.9)
  Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 125)
  Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 125)
  Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 124.8)
  lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 121.6)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 120.4)
  phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 119)
  Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 118.1)
  Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 116.1)
  Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 115.6)
  Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 115.6)
  Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 114.4)
  Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 114.4)
  proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 114.1)
  Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 113.3)
  ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 112.9)
  gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 112.5)
  Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 108.6)
  Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 108.6)
  thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 108)
  Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 102.9)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 102.4)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 92.5)
  Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 92.4)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 89.6)
  Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 89.6)
  Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 87.8)
  Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 85.7)
  Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 85.7)
  Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 85.7)
  ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 85.3)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 84.7)
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 76.2)
  Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 74)
  Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 66.8)
  Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 66.8)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 56.7)
  Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 50.3)
  Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 47.3)
  Metabolism Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 46.8)
  Metabolism Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 38.5)
  Unknown function General Mg chelatase-like protein (TIGR00368; HMM-score: 15.8)
  Metabolism Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 14.5)
  Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions guanylate kinase (TIGR03263; EC 2.7.4.8; HMM-score: 13.6)
  Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YjeE (TIGR00150; HMM-score: 13.5)
  Cellular processes Cellular processes Chemotaxis and motility flagellar biosynthesis protein FlhF (TIGR03499; HMM-score: 12.6)
  Metabolism Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 12.1)
  Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 11.9)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaA regulatory inactivator Hda (TIGR03420; HMM-score: 11.5)
  rad50 (TIGR00606; HMM-score: 10.2)
  Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 9.4)
  Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 9.4)
• TheSEED: data available for Hungary19A-6, TIGR4
• ⊞⊞PFAM:
  P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 122.2)
  and 33 more
  SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 37.5)
  AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 33.5)
  AAA_13; AAA domain (PF13166; HMM-score: 24.9)
  AAA_30; AAA domain (PF13604; HMM-score: 23)
  RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 22.6)
  AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 22.5)
  ABC_ATPase; ATPase of the ABC class (PF09818; HMM-score: 21.8)
  AAA_23; AAA domain (PF13476; HMM-score: 21.3)
  AAA_16; AAA ATPase domain (PF13191; HMM-score: 19.5)
  AAA_10; AAA-like domain (PF12846; HMM-score: 17.4)
  AAA_22; AAA domain (PF13401; HMM-score: 17)
  ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 16.2)
  AAA_33; AAA domain (PF13671; HMM-score: 15.7)
  AAA_18; AAA domain (PF13238; HMM-score: 15.2)
  DLIC; Dynein light intermediate chain (DLIC) (PF05783; HMM-score: 15.1)
  AAA_24; AAA domain (PF13479; HMM-score: 14.6)
  NACHT; NACHT domain (PF05729; HMM-score: 14)
  cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 13.7)
  AAA_5; AAA domain (dynein-related subfamily) (PF07728; HMM-score: 13.7)
  IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 13.5)
  MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 13.5)
  TsaE; Threonylcarbamoyl adenosine biosynthesis protein TsaE (PF02367; HMM-score: 13.5)
  AAA_PrkA; PrkA AAA domain (PF08298; HMM-score: 13.3)
  SbcC_Walker_B; SbcC/RAD50-like, Walker B motif (PF13558; HMM-score: 13.3)
  Rad17; Rad17 P-loop domain (PF03215; HMM-score: 13.1)
  Mg_chelatase; Magnesium chelatase, subunit ChlI (PF01078; HMM-score: 13)
  G-alpha; G-protein alpha subunit (PF00503; HMM-score: 12.7)
  DAP3; Mitochondrial ribosomal death-associated protein 3 (PF10236; HMM-score: 12.4)
  SH3 (CL0010) SH3_2; Variant SH3 domain (PF07653; HMM-score: 12)
  P-loop_NTPase (CL0023) DUF815; Protein of unknown function (DUF815) (PF05673; HMM-score: 11.8)
  AAA_28; AAA domain (PF13521; HMM-score: 11.8)
  NB-ARC; NB-ARC domain (PF00931; HMM-score: 11.4)
  Adeno_IVa2; Adenovirus IVa2 protein (PF02456; HMM-score: 11.1)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0.01
  • Cytoplasmic Membrane Score: 9.99
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 0
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.008682
  • TAT(Tat/SPI): 0.000577
  • LIPO(Sec/SPII): 0.000543
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: BBA59637 NCBI
• UniProt:

⊟Protein sequence

• MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKSTLIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKTVLENVTLAPVKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPELLLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVLVDTTDVDNFFDNPSEPRAQQFLSKIINHESDKVK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Expression data

• PneumoExpress for strain D39V: SPV_0531 PneumoExpress

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications