UndoCtrl+ZRedoCtrl+Shift+Z, Ctrl+Y
LinkCtrl+K

Links

Link important words to other wiki articles or even other websites. It will help readers understand the context.

Okay, got it
Special character
Edit notices
Save changes…Alt+S
ParagraphCtrl+0HeadingCtrl+2Sub-heading 1Ctrl+3Sub-heading 2Ctrl+4Sub-heading 3Ctrl+5Sub-heading 4Ctrl+6Header cellContent cellPreformattedCtrl+7Block quoteCtrl+8Page titleCtrl+1
BoldCtrl+BItalicCtrl+ISuperscriptCtrl+.SubscriptCtrl+,Computer codeCtrl+Shift+6StrikethroughCtrl+Shift+5UnderlineCtrl+UBigSmallLanguageRemoveCtrl+\, Ctrl+MMore
PubMedBasicCtrl+Shift+KRe-useMore
Bullet listNumbered listDecrease indentationShift+Tab, Ctrl+[Increase indentationTab, Ctrl+]More
Images and mediaTemplateTableCommentGalleryYour signatureReferences listMore
Read the user guideKeyboard shortcutsCtrl+/, Ctrl+Shift+/Toolbar searchCtrl+Shift+P, Ctrl+Alt+Shift+P
More
2 noticesClose
Warning: You are not logged in. Your IP address will be publicly visible if you make any edits. If you log in or create an account, your edits will be attributed to your username, along with other benefits.

You are using a browser which is not officially supported by this editor.

OptionsCategoriesPage settingsAdvanced settingsLanguagesTemplates used⧼visualeditor-changedir-rtl⧽Ctrl+Shift+XFind and replaceCtrl+FMore
Visual editingSource editingMore
From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 05-OCT-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • pan locus tag?: PNEUPAN002686000
  • symbol: hom
  • pan gene symbol?: hom
  • synonym:
  • product: homoserine dehydrogenase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • symbol: hom
  • product: homoserine dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 735002..736288
  • length: 1287
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AP018391 (735002..736288) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1195 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGACAGTTAAAATTGCTTTACTAGGATTTGGTACCGTTGCAAGTGGTGTGCCTTTCCTC
    CTAAAGGAAAATGGAGGAAAAATCAATCAATCAGCACATTCAGATATCAAAGTTGCTAAG
    GTATTGGTCAAGGATGAAGATGAAAAAAATCGCTTGCTTGCAGCAGGGAATGACTTTAAC
    TTTGTAACCAATGTGGATGATATTTTATCAGACCAGGATATTACTATCGTAGTGGAATTG
    ATGGGGCGTATTGAGCCTGCTAAAACCTTTATCACTCGTGCCTTGGAAGCTGGAAAACAC
    GTTGTTACTGCTAACAAGGACCTTTTAGCTGTCCATGGCGCAGAATTGCTAGAAATCGCT
    CAAGCTAACAAGGTAGCACTTTACTACGAAGCAGCAGTTGCTGGTGGGATTCCAATTCTT
    CGTACTTTAGCAAATTCCTTGGCTTCTGATAAAATTACGCGCGTGCTTGGAGTAGTCAAC
    GGAACTTCCAACTTCATGGTGACCAAGATGGTGGAAGAAGGCTGGTCTTACGATGATGCT
    CTTGCGGAAGCACAACGTCTAGGATTTGCAGAAAGCGATCCGACGAATGACGTAGATGGG
    ATTGATGCAGCCTACAAGATGGTTATTTTGAGCCAATTTGCCTTTGGCATGAAGATTGCC
    TTTGATGATGTAGCCCACAAGGGAATCCGCAATATCACACCAGAAGACGTAGCTGTAGCT
    CAAGAGCTTGGTTACGTAGTGAAATTGGTTGGTTCTATTGAGGAAACTTCTTCAGGTATT
    GCTGCAGAAGTGACTCCAACCTTCCTACCTAAAGCGCACCCACTTGCTAGTGTGAATGGC
    GTAATGAACGCTGTCTTTGTAGAATCTATCGGTATTGGTGAGTCTATGTACTACGGACCA
    GGTGCGGGTCAAAAACCAACTGCAACAAGTGTTGTAGCTGATATTGTCCGTATCGTTCGT
    CGTTTGAATGATGGTACTATTGGCAAAGACTTCAACGAATATAGCCGTGACTTGGTCTTG
    GCAAATCCTGAAGATGTCAAAGCAAACTACTATTTCTCAATCTTGGCTCTAGACTCAAAA
    GGTCAGGTCTTGAAGTTGGCTGAAATCTTCAATGCTCAAGATATTTCCTTTAAGCAAATC
    CTTCAAGATGGCAAAGAGGGTGACAAGGCGCGTGTCGTTATCATCACACACAAGATTAAT
    AAAGCCCAGCTTGAAAATGTCTCAGCTGAATTGAAGAAGGTTTCAGAATTCGACCTCTTG
    AATACCTTCAAGGTGCTAGGAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1287

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • symbol: Hom
  • description: homoserine dehydrogenase
  • length: 428
  • theoretical pI: 4.79015
  • theoretical MW: 46119.4
  • GRAVY: 0.0771028

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞⊞PFAM:
    GADPH_aa-bio_dh (CL0139) Homoserine_dh; Homoserine dehydrogenase (PF00742; HMM-score: 210.1)
    and 3 more
    NADP_Rossmann (CL0063) NAD_binding_3; Homoserine dehydrogenase, NAD binding domain (PF03447; HMM-score: 64.2)
    ACT (CL0070) ACT; ACT domain (PF01842; HMM-score: 21.6)
    NADP_Rossmann (CL0063) GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold (PF01408; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.263331
    • TAT(Tat/SPI): 0.012599
    • LIPO(Sec/SPII): 0.032082
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBA58931 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVKDEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVVTANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVNGTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMKIAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLASVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEYSRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARVVIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=MDRSPN_00725&oldid=108163"
Insert paragraph

NCBI: 05-OCT-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • pan locus tag?: PNEUPAN002686000
  • symbol: hom
  • pan gene symbol?: hom
  • synonym:
  • product: homoserine dehydrogenase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • symbol: hom
  • product: homoserine dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 735002..736288
  • length: 1287
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: AP018391 (735002..736288) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1195 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGACAGTTAAAATTGCTTTACTAGGATTTGGTACCGTTGCAAGTGGTGTGCCTTTCCTC
    CTAAAGGAAAATGGAGGAAAAATCAATCAATCAGCACATTCAGATATCAAAGTTGCTAAG
    GTATTGGTCAAGGATGAAGATGAAAAAAATCGCTTGCTTGCAGCAGGGAATGACTTTAAC
    TTTGTAACCAATGTGGATGATATTTTATCAGACCAGGATATTACTATCGTAGTGGAATTG
    ATGGGGCGTATTGAGCCTGCTAAAACCTTTATCACTCGTGCCTTGGAAGCTGGAAAACAC
    GTTGTTACTGCTAACAAGGACCTTTTAGCTGTCCATGGCGCAGAATTGCTAGAAATCGCT
    CAAGCTAACAAGGTAGCACTTTACTACGAAGCAGCAGTTGCTGGTGGGATTCCAATTCTT
    CGTACTTTAGCAAATTCCTTGGCTTCTGATAAAATTACGCGCGTGCTTGGAGTAGTCAAC
    GGAACTTCCAACTTCATGGTGACCAAGATGGTGGAAGAAGGCTGGTCTTACGATGATGCT
    CTTGCGGAAGCACAACGTCTAGGATTTGCAGAAAGCGATCCGACGAATGACGTAGATGGG
    ATTGATGCAGCCTACAAGATGGTTATTTTGAGCCAATTTGCCTTTGGCATGAAGATTGCC
    TTTGATGATGTAGCCCACAAGGGAATCCGCAATATCACACCAGAAGACGTAGCTGTAGCT
    CAAGAGCTTGGTTACGTAGTGAAATTGGTTGGTTCTATTGAGGAAACTTCTTCAGGTATT
    GCTGCAGAAGTGACTCCAACCTTCCTACCTAAAGCGCACCCACTTGCTAGTGTGAATGGC
    GTAATGAACGCTGTCTTTGTAGAATCTATCGGTATTGGTGAGTCTATGTACTACGGACCA
    GGTGCGGGTCAAAAACCAACTGCAACAAGTGTTGTAGCTGATATTGTCCGTATCGTTCGT
    CGTTTGAATGATGGTACTATTGGCAAAGACTTCAACGAATATAGCCGTGACTTGGTCTTG
    GCAAATCCTGAAGATGTCAAAGCAAACTACTATTTCTCAATCTTGGCTCTAGACTCAAAA
    GGTCAGGTCTTGAAGTTGGCTGAAATCTTCAATGCTCAAGATATTTCCTTTAAGCAAATC
    CTTCAAGATGGCAAAGAGGGTGACAAGGCGCGTGTCGTTATCATCACACACAAGATTAAT
    AAAGCCCAGCTTGAAAATGTCTCAGCTGAATTGAAGAAGGTTTCAGAATTCGACCTCTTG
    AATACCTTCAAGGTGCTAGGAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1287

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_00725 [new locus tag: MDRSPN_RS03860 ]
  • symbol: Hom
  • description: homoserine dehydrogenase
  • length: 428
  • theoretical pI: 4.79015
  • theoretical MW: 46119.4
  • GRAVY: 0.0771028

Insert paragraph

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞PFAM:
    GADPH_aa-bio_dh (CL0139) Homoserine_dh; Homoserine dehydrogenase (PF00742; HMM-score: 210.1)
    and 3 more
    NADP_Rossmann (CL0063) NAD_binding_3; Homoserine dehydrogenase, NAD binding domain (PF03447; HMM-score: 64.2)
    ACT (CL0070) ACT; ACT domain (PF01842; HMM-score: 21.6)
    NADP_Rossmann (CL0063) GFO_IDH_MocA; Oxidoreductase family, NAD-binding Rossmann fold (PF01408; HMM-score: 13.5)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.263331
    • TAT(Tat/SPI): 0.012599
    • LIPO(Sec/SPII): 0.032082
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBA58931 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVKDEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVVTANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVNGTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMKIAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLASVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEYSRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARVVIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph