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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1486 [new locus tag: SPAP_RS07315 ]
  • symbol: SPAP_1486
  • product: Thioredoxin reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1399196..1400107
  • length: 912
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTACGATACTATTATTATCGGTGCTGGACCTGCAGGGATGACTGCGGCCTTGTATGCT
    GCTCGAAGCAATCTAAAAGTAGCTTTGATTGAAGGTGGTCTGCCAGGTGGTCAGATGAAT
    AATACATCTGATATCGAAAATTACCCAGGATACGCTAATATTAGTGGACCTGAATTGGCT
    GAAAAGATGTTTGAACCACTTGAAAATCTTGGTGTTGAGCACATTTATGGTTATGTTGAA
    AATGTCGAAGACCATGGTGATTTTAAGAAAGTGATGACTGATGACCAAACATATGAAACA
    CGTACAGTTATCGTAGCAACTGGTTCTAAACACCGTCCTTTGGGAGTGCCTGGAGAAGAA
    GAACTGAACAGTCGTGGTGTTTCTTACTGTGCTGTGTGTGATGGTGCTTTCTTCCGTGAC
    CAAGATTTATTGATAGTTGGTGGTGGAGATTCAGCTGTTGAAGAAGCCCTCTTCTTGACT
    CGTTTTGCTAAGACTGTTACCATTGTTCACCGTCGTGACCAACTTCGTGCCCAAAAGGTT
    TTACAAGATCGCGCCTTTGCGAATGAAAAAATCAGCTTTATCTGGGATTCTGTAGTAAGG
    GAAATCAAGGGTGAAAACCGAGTAGAATCAGTCGTATTTGAAAATGTGAAAACAGGTCAA
    GTGACAGAACAAGCCTTCGGTGGTGTCTTTATCTATGTTGGTTTGGACCCTCTTAGCGAT
    TTTGTTAAAGAATTGAATATCCAAGATCAGGCAGGCTGGATTGTGACAGATAGCCACATG
    AAGACTGCAGTCGACGGTATCTTTGCAGTTGGAGATGTTCGCTTGAAAGACCTTCGCCAA
    GTAACAACAGCAGTTGGAGATGGAGCTATCGCTGGTCAAGAAGCCTACAAGTTTATCACA
    GAACATAGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPAP_1486 [new locus tag: SPAP_RS07315 ]
  • symbol: SPAP_1486
  • description: Thioredoxin reductase
  • length: 303
  • theoretical pI: 4.50525
  • theoretical MW: 33134.1
  • GRAVY: -0.155776

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport thioredoxin-disulfide reductase (TIGR01292; EC 1.8.1.9; HMM-score: 388.6)
    putative alkyl hydroperoxide reductase F subunit (TIGR03143; EC 1.6.4.-; HMM-score: 321.1)
    and 44 more
    Cellular processes Cellular processes Detoxification alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 241.6)
    Cellular processes Cellular processes Adaptations to atypical conditions alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 241.6)
    Unknown function Enzymes of unknown specificity putative bacillithiol system oxidoreductase, YpdA family (TIGR04018; EC 1.8.-.-; HMM-score: 95.5)
    dihydrolipoyl dehydrogenase (TIGR01350; EC 1.8.1.4; HMM-score: 94)
    Cellular processes Cellular processes Detoxification mercury(II) reductase (TIGR02053; EC 1.16.1.1; HMM-score: 70.3)
    thioredoxin and glutathione reductase (TIGR01438; EC 1.6.4.-; HMM-score: 54)
    Cellular processes Cellular processes Detoxification CoA-disulfide reductase (TIGR03385; EC 1.8.1.14; HMM-score: 52.2)
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01421; EC 1.8.1.7; HMM-score: 46.9)
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01424; EC 1.8.1.7; HMM-score: 45.7)
    Unknown function Enzymes of unknown specificity flavoprotein, HI0933 family (TIGR00275; HMM-score: 41)
    putative selenate reductase, YgfK subunit (TIGR03315; HMM-score: 41)
    mycofactocin system FadH/OYE family oxidoreductase 2 (TIGR03997; EC 1.-.-.-; HMM-score: 39.5)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, alpha subunit family (TIGR01372; HMM-score: 35.8)
    Metabolism Amino acid biosynthesis Glutamate family glutamate synthase (NADPH), homotetrameric (TIGR01316; EC 1.4.1.13; HMM-score: 35.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll geranylgeranyl reductase family (TIGR02032; EC 1.3.1.-; HMM-score: 33.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiazole biosynthesis enzyme (TIGR00292; HMM-score: 32.7)
    mycofactocin system FadH/OYE family oxidoreductase 1 (TIGR03996; EC 1.-.-.-; HMM-score: 28.8)
    mycothione reductase (TIGR03452; EC 1.8.1.15; HMM-score: 27.9)
    lycopene cyclase family protein (TIGR01790; HMM-score: 26.8)
    Metabolism Central intermediary metabolism Nitrogen metabolism nitrite reductase [NAD(P)H], large subunit (TIGR02374; EC 1.7.1.4; HMM-score: 24.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family (TIGR01988; EC 1.14.13.-; HMM-score: 23.6)
    trypanothione-disulfide reductase (TIGR01423; EC 1.8.1.12; HMM-score: 21.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA (TIGR00136; HMM-score: 20.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine glycine oxidase ThiO (TIGR02352; EC 1.4.3.19; HMM-score: 20)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-polyprenyl-6-methoxyphenol 4-hydroxylase (TIGR01984; EC 1.14.13.-; HMM-score: 19.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides L-aspartate oxidase (TIGR00551; EC 1.4.3.16; HMM-score: 19.2)
    flavin-dependent oxidoreductase, MSMEG_0569 family (TIGR04046; HMM-score: 18.6)
    Metabolism Energy metabolism TCA cycle succinate dehydrogenase, flavoprotein subunit (TIGR01816; HMM-score: 18)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll geranylgeranyl reductase (TIGR02023; EC 1.3.1.-; HMM-score: 17.5)
    Metabolism Energy metabolism Anaerobic glycerol-3-phosphate dehydrogenase, anaerobic, B subunit (TIGR03378; EC 1.1.5.3; HMM-score: 17.2)
    Metabolism Energy metabolism TCA cycle succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    Metabolism Energy metabolism Anaerobic succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    Metabolism Energy metabolism Aerobic succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    squalene-associated FAD-dependent desaturase (TIGR03467; HMM-score: 16.2)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, beta subunit family (TIGR01373; HMM-score: 15.6)
    glutamate synthase, NADH/NADPH, small subunit (TIGR01317; EC 1.4.1.-; HMM-score: 14.9)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, monomeric form (TIGR01377; HMM-score: 14.9)
    FAD dependent oxidoreductase TIGR03364 (TIGR03364; HMM-score: 14.7)
    fumarate reductase (quinol), flavoprotein subunit (TIGR01176; EC 1.3.5.4; HMM-score: 14.3)
    glutamate synthase, small subunit (TIGR01318; HMM-score: 14)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-galactopyranose mutase (TIGR00031; EC 5.4.99.9; HMM-score: 13.5)
    Metabolism Energy metabolism Electron transport flavocytochrome c (TIGR01813; HMM-score: 13.4)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain (TIGR03197; HMM-score: 12.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin 3B synthase CobZ (TIGR02485; HMM-score: 11.6)
  • TheSEED  :
    • Thioredoxin reductase (EC 1.8.1.9)
    Nucleosides and Nucleotides Pyrimidines pyrimidine conversions  Thioredoxin reductase (EC 1.8.1.9)
    and 1 more
    Sulfur Metabolism Sulfur Metabolism - no subcategory Thioredoxin-disulfide reductase  Thioredoxin reductase (EC 1.8.1.9)
  • PFAM:
    NADP_Rossmann (CL0063) Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 166.6)
    and 15 more
    Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 97.7)
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase (PF00070; HMM-score: 77.6)
    DAO; FAD dependent oxidoreductase (PF01266; HMM-score: 44.8)
    FAD_oxidored; FAD dependent oxidoreductase (PF12831; HMM-score: 36.7)
    FAD_binding_2; FAD binding domain (PF00890; HMM-score: 35.7)
    GIDA; Glucose inhibited division protein A (PF01134; HMM-score: 34.9)
    HI0933_like; HI0933-like protein (PF03486; HMM-score: 33.1)
    Lycopene_cycl; Lycopene cyclase protein (PF05834; HMM-score: 31)
    Thi4; Thi4 family (PF01946; HMM-score: 29.8)
    NAD_binding_8; NAD(P)-binding Rossmann-like domain (PF13450; HMM-score: 27.4)
    NAD_binding_9; FAD-NAD(P)-binding (PF13454; HMM-score: 20.1)
    NAD_binding_7; Putative NAD(P)-binding (PF13241; HMM-score: 19.9)
    FAD_binding_3; FAD binding domain (PF01494; HMM-score: 18.9)
    Trp_halogenase; Tryptophan halogenase (PF04820; HMM-score: 12.4)
    MCRA; MCRA family (PF06100; HMM-score: 11.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.123075
    • TAT(Tat/SPI): 0.022348
    • LIPO(Sec/SPII): 0.052237
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85072 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLIVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 17-JAN-2018

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1486 [new locus tag: SPAP_RS07315 ]
  • pan locus tag?: PNEUPAN002782000
  • symbol: SPAP_1486
  • pan gene symbol?: trxB
  • synonym:
  • product: Thioredoxin reductase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1486 [new locus tag: SPAP_RS07315 ]
  • symbol: SPAP_1486
  • product: Thioredoxin reductase
  • replicon: chromosome
  • strand: -
  • coordinates: 1399196..1400107
  • length: 912
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTACGATACTATTATTATCGGTGCTGGACCTGCAGGGATGACTGCGGCCTTGTATGCT
    GCTCGAAGCAATCTAAAAGTAGCTTTGATTGAAGGTGGTCTGCCAGGTGGTCAGATGAAT
    AATACATCTGATATCGAAAATTACCCAGGATACGCTAATATTAGTGGACCTGAATTGGCT
    GAAAAGATGTTTGAACCACTTGAAAATCTTGGTGTTGAGCACATTTATGGTTATGTTGAA
    AATGTCGAAGACCATGGTGATTTTAAGAAAGTGATGACTGATGACCAAACATATGAAACA
    CGTACAGTTATCGTAGCAACTGGTTCTAAACACCGTCCTTTGGGAGTGCCTGGAGAAGAA
    GAACTGAACAGTCGTGGTGTTTCTTACTGTGCTGTGTGTGATGGTGCTTTCTTCCGTGAC
    CAAGATTTATTGATAGTTGGTGGTGGAGATTCAGCTGTTGAAGAAGCCCTCTTCTTGACT
    CGTTTTGCTAAGACTGTTACCATTGTTCACCGTCGTGACCAACTTCGTGCCCAAAAGGTT
    TTACAAGATCGCGCCTTTGCGAATGAAAAAATCAGCTTTATCTGGGATTCTGTAGTAAGG
    GAAATCAAGGGTGAAAACCGAGTAGAATCAGTCGTATTTGAAAATGTGAAAACAGGTCAA
    GTGACAGAACAAGCCTTCGGTGGTGTCTTTATCTATGTTGGTTTGGACCCTCTTAGCGAT
    TTTGTTAAAGAATTGAATATCCAAGATCAGGCAGGCTGGATTGTGACAGATAGCCACATG
    AAGACTGCAGTCGACGGTATCTTTGCAGTTGGAGATGTTCGCTTGAAAGACCTTCGCCAA
    GTAACAACAGCAGTTGGAGATGGAGCTATCGCTGGTCAAGAAGCCTACAAGTTTATCACA
    GAACATAGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    912

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPAP_1486 [new locus tag: SPAP_RS07315 ]
  • symbol: SPAP_1486
  • description: Thioredoxin reductase
  • length: 303
  • theoretical pI: 4.50525
  • theoretical MW: 33134.1
  • GRAVY: -0.155776

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Electron transport thioredoxin-disulfide reductase (TIGR01292; EC 1.8.1.9; HMM-score: 388.6)
    putative alkyl hydroperoxide reductase F subunit (TIGR03143; EC 1.6.4.-; HMM-score: 321.1)
    and 44 more
    Cellular processes Cellular processes Detoxification alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 241.6)
    Cellular processes Cellular processes Adaptations to atypical conditions alkyl hydroperoxide reductase subunit F (TIGR03140; EC 1.8.1.-; HMM-score: 241.6)
    Unknown function Enzymes of unknown specificity putative bacillithiol system oxidoreductase, YpdA family (TIGR04018; EC 1.8.-.-; HMM-score: 95.5)
    dihydrolipoyl dehydrogenase (TIGR01350; EC 1.8.1.4; HMM-score: 94)
    Cellular processes Cellular processes Detoxification mercury(II) reductase (TIGR02053; EC 1.16.1.1; HMM-score: 70.3)
    thioredoxin and glutathione reductase (TIGR01438; EC 1.6.4.-; HMM-score: 54)
    Cellular processes Cellular processes Detoxification CoA-disulfide reductase (TIGR03385; EC 1.8.1.14; HMM-score: 52.2)
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01421; EC 1.8.1.7; HMM-score: 46.9)
    Metabolism Energy metabolism Electron transport glutathione-disulfide reductase (TIGR01424; EC 1.8.1.7; HMM-score: 45.7)
    Unknown function Enzymes of unknown specificity flavoprotein, HI0933 family (TIGR00275; HMM-score: 41)
    putative selenate reductase, YgfK subunit (TIGR03315; HMM-score: 41)
    mycofactocin system FadH/OYE family oxidoreductase 2 (TIGR03997; EC 1.-.-.-; HMM-score: 39.5)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, alpha subunit family (TIGR01372; HMM-score: 35.8)
    Metabolism Amino acid biosynthesis Glutamate family glutamate synthase (NADPH), homotetrameric (TIGR01316; EC 1.4.1.13; HMM-score: 35.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll geranylgeranyl reductase family (TIGR02032; EC 1.3.1.-; HMM-score: 33.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiazole biosynthesis enzyme (TIGR00292; HMM-score: 32.7)
    mycofactocin system FadH/OYE family oxidoreductase 1 (TIGR03996; EC 1.-.-.-; HMM-score: 28.8)
    mycothione reductase (TIGR03452; EC 1.8.1.15; HMM-score: 27.9)
    lycopene cyclase family protein (TIGR01790; HMM-score: 26.8)
    Metabolism Central intermediary metabolism Nitrogen metabolism nitrite reductase [NAD(P)H], large subunit (TIGR02374; EC 1.7.1.4; HMM-score: 24.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family (TIGR01988; EC 1.14.13.-; HMM-score: 23.6)
    trypanothione-disulfide reductase (TIGR01423; EC 1.8.1.12; HMM-score: 21.9)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA (TIGR00136; HMM-score: 20.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine glycine oxidase ThiO (TIGR02352; EC 1.4.3.19; HMM-score: 20)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-polyprenyl-6-methoxyphenol 4-hydroxylase (TIGR01984; EC 1.14.13.-; HMM-score: 19.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides L-aspartate oxidase (TIGR00551; EC 1.4.3.16; HMM-score: 19.2)
    flavin-dependent oxidoreductase, MSMEG_0569 family (TIGR04046; HMM-score: 18.6)
    Metabolism Energy metabolism TCA cycle succinate dehydrogenase, flavoprotein subunit (TIGR01816; HMM-score: 18)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll geranylgeranyl reductase (TIGR02023; EC 1.3.1.-; HMM-score: 17.5)
    Metabolism Energy metabolism Anaerobic glycerol-3-phosphate dehydrogenase, anaerobic, B subunit (TIGR03378; EC 1.1.5.3; HMM-score: 17.2)
    Metabolism Energy metabolism TCA cycle succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    Metabolism Energy metabolism Anaerobic succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    Metabolism Energy metabolism Aerobic succinate dehydrogenase or fumarate reductase, flavoprotein subunit (TIGR01812; HMM-score: 17.1)
    squalene-associated FAD-dependent desaturase (TIGR03467; HMM-score: 16.2)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, beta subunit family (TIGR01373; HMM-score: 15.6)
    glutamate synthase, NADH/NADPH, small subunit (TIGR01317; EC 1.4.1.-; HMM-score: 14.9)
    Metabolism Energy metabolism Amino acids and amines sarcosine oxidase, monomeric form (TIGR01377; HMM-score: 14.9)
    FAD dependent oxidoreductase TIGR03364 (TIGR03364; HMM-score: 14.7)
    fumarate reductase (quinol), flavoprotein subunit (TIGR01176; EC 1.3.5.4; HMM-score: 14.3)
    glutamate synthase, small subunit (TIGR01318; HMM-score: 14)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-galactopyranose mutase (TIGR00031; EC 5.4.99.9; HMM-score: 13.5)
    Metabolism Energy metabolism Electron transport flavocytochrome c (TIGR01813; HMM-score: 13.4)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA U-34 5-methylaminomethyl-2-thiouridine biosynthesis protein MnmC, C-terminal domain (TIGR03197; HMM-score: 12.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin 3B synthase CobZ (TIGR02485; HMM-score: 11.6)
  • TheSEED  :
    • Thioredoxin reductase (EC 1.8.1.9)
    Nucleosides and Nucleotides Pyrimidines pyrimidine conversions  Thioredoxin reductase (EC 1.8.1.9)
    and 1 more
    Sulfur Metabolism Sulfur Metabolism - no subcategory Thioredoxin-disulfide reductase  Thioredoxin reductase (EC 1.8.1.9)
  • PFAM:
    NADP_Rossmann (CL0063) Pyr_redox_2; Pyridine nucleotide-disulphide oxidoreductase (PF07992; HMM-score: 166.6)
    and 15 more
    Pyr_redox_3; Pyridine nucleotide-disulphide oxidoreductase (PF13738; HMM-score: 97.7)
    Pyr_redox; Pyridine nucleotide-disulphide oxidoreductase (PF00070; HMM-score: 77.6)
    DAO; FAD dependent oxidoreductase (PF01266; HMM-score: 44.8)
    FAD_oxidored; FAD dependent oxidoreductase (PF12831; HMM-score: 36.7)
    FAD_binding_2; FAD binding domain (PF00890; HMM-score: 35.7)
    GIDA; Glucose inhibited division protein A (PF01134; HMM-score: 34.9)
    HI0933_like; HI0933-like protein (PF03486; HMM-score: 33.1)
    Lycopene_cycl; Lycopene cyclase protein (PF05834; HMM-score: 31)
    Thi4; Thi4 family (PF01946; HMM-score: 29.8)
    NAD_binding_8; NAD(P)-binding Rossmann-like domain (PF13450; HMM-score: 27.4)
    NAD_binding_9; FAD-NAD(P)-binding (PF13454; HMM-score: 20.1)
    NAD_binding_7; Putative NAD(P)-binding (PF13241; HMM-score: 19.9)
    FAD_binding_3; FAD binding domain (PF01494; HMM-score: 18.9)
    Trp_halogenase; Tryptophan halogenase (PF04820; HMM-score: 12.4)
    MCRA; MCRA family (PF06100; HMM-score: 11.1)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.123075
    • TAT(Tat/SPI): 0.022348
    • LIPO(Sec/SPII): 0.052237
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM85072 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSDIENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRTVIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLIVGGGDSAVEEALFLTRFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKTGQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLKDLRQVTTAVGDGAIAGQEAYKFITEHS

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]