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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS07115 [old locus tags: SPNOXC13200 SPNOXC_13200 ]
  • pan locus tag?: PNEUPAN002832000
  • symbol: atpD
  • pan gene symbol?: atpD
  • synonym:
  • product: F0F1 ATP synthase subunit beta

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS07115 [old locus tags: SPNOXC13200 SPNOXC_13200 ]
  • symbol: atpD
  • product: F0F1 ATP synthase subunit beta
  • replicon: chromosome
  • strand: -
  • coordinates: 1340100..1341506
  • length: 1407
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (1340100..1341506) NCBI
  • BioCyc: SPNOXC_RS07115 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1335 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGAGTTCAGGTAAAATTGCTCAGGTTATCGGTCCCGTTGTAGACGTTTTGTTTGCAGCA
    GGGGAAAAACTTCCTGAGATTAATAATGCACTTGTCGTCTACAAAAATGACGAAAGAAAA
    ACAAAAATCGTCCTTGAAGTAGCCTTGGAGTTAGGAGATGGTATGGTTCGTACTATCGCC
    ATGGAATCAACAGATGGGTTGACTCGTGGAATGGAAGTATTGGACACAGGTCGTCCAATC
    TCTGTACCAGTAGGTAAAGAAACTTTGGGACGTGTCTTCAACGTTTTGGGAGATACCATT
    GATTTGGAAGCTCCTTTTACAGAAGACGCAGAGCGTCAGCCAATTCATAAAAAAGCTCCA
    ACTTTTGATGAGTTGTCTACCTCTTCTGAAATCCTTGAAACAGGGATCAAGGTTATTGAC
    CTTCTTGCCCCTTACCTTAAAGGTGGTAAAGTTGGACTTTTCGGTGGTGCCGGAGTTGGT
    AAAACCGTCTTAATCCAAGAATTGATTCACAACATTGCCCAAGAGCACGGTGGTATTTCA
    GTATTTGCTGGTGTTGGGGAACGTACTCGTGAGGGGAATGACCTTTACTGGGAAATGAAA
    GAATCAGGCGTTATCGAGAAAACAGCCATGGTCTTTGGTCAGATGAATGAGCCACCAGGA
    GCACGTATGCGTGTTGCCCTTACTGGTTTGACAATCGCTGAATACTTCCGTGATGTGGAA
    GGCCAAGACGTGCTTCTCTTTATCGATAATATCTTCCGTTTCACTCAGGCTGGTTCAGAA
    GTATCTGCCCTTTTGGGTCGTATGCCATCAGCCGTTGGTTACCAACCAACACTTGCTACG
    GAAATGGGTCAATTGCAAGAACGTATCACATCAACCAAGAAGGGTTCTGTAACCTCTATC
    CAGGCTATCTATGTGCCAGCGGATGACTATACTGACCCAGCGCCAGCAACAGCCTTCGCT
    CACTTGGATTCAACAACAAACTTGGAACGTAAGTTGGTACAATTGGGTATCTACCCAGCC
    GTTGACCCACTTGCTTCAAGCTCACGTGCCTTGGCACCTGAAATCGTTGGAGAAGAGCAC
    TATGCAGTTGCTGCTGAAGTAAAACGTGTCCTTCAACGTTACCATGAATTGCAAGATATC
    ATTGCTATCCTTGGTATGGATGAGCTTTCTGATGAAGAAAAGACCTTGGTTGCTCGCGCC
    CGTCGTATCCAGTTCTTCTTGTCACAAAACTTCAACGTTGCGGAACAATTTACTGGTCAG
    CCAGGTTCTTATGTTCCAGTTGCTGAAACTGTACGTGGCTTTAAGGAAATCCTTGATGGT
    AAATACGACCACTTGCCAGAAGATGCCTTCCGTGGTGTAGGTTCTATCGAAGATGTGATT
    GCAAAAGCTGAAAAAATGGGATTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1407

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS07115 [old locus tags: SPNOXC13200 SPNOXC_13200 ]
  • symbol: AtpD
  • description: F0F1 ATP synthase subunit beta
  • length: 468
  • theoretical pI: 4.57824
  • theoretical MW: 50903.7
  • GRAVY: -0.0735043

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 7.1.2.2?  ExPASy
    non-specified enzyme name
  • ⊞TIGRFAM:
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F1, beta subunit (TIGR01039; EC 3.6.3.14; HMM-score: 837.5)
    and 15 more
    alternate F1F0 ATPase, F1 subunit beta (TIGR03305; EC 3.6.3.-; HMM-score: 587.9)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATPase, FliI/YscN family (TIGR01026; EC 3.6.3.14; HMM-score: 232.3)
    Cellular processes Cellular processes Pathogenesis type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 228.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type III secretion apparatus H+-transporting two-sector ATPase (TIGR02546; EC 3.6.3.14; HMM-score: 228.4)
    Cellular processes Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03496; EC 3.6.3.14; HMM-score: 225.2)
    flagellar protein export ATPase FliI (TIGR03498; EC 3.6.3.14; HMM-score: 221.6)
    Cellular processes Cellular processes Chemotaxis and motility flagellar protein export ATPase FliI (TIGR03497; EC 3.6.3.14; HMM-score: 218.8)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase archaeal, B subunit (TIGR01041; EC 3.6.3.14; HMM-score: 141.8)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase archaeal, A subunit (TIGR01043; EC 3.6.3.14; HMM-score: 134.3)
    alternate F1F0 ATPase, F1 subunit alpha (TIGR03324; EC 3.6.3.-; HMM-score: 127.3)
    Metabolism Transport and binding proteins Cations and iron carrying compounds V-type ATPase, A subunit (TIGR01042; EC 3.6.3.14; HMM-score: 126.2)
    Metabolism Energy metabolism ATP-proton motive force interconversion ATP synthase F1, alpha subunit (TIGR00962; EC 3.6.3.14; HMM-score: 120.4)
    Metabolism Transport and binding proteins Cations and iron carrying compounds V-type ATPase, B subunit (TIGR01040; EC 3.6.3.14; HMM-score: 96.9)
    Genetic information processing Transcription Transcription factors transcription termination factor Rho (TIGR00767; EC 3.6.4.-; HMM-score: 39.8)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 12.5)
  • TheSEED: see SPNOXC13200
  • ⊞PFAM:
    P-loop_NTPase (CL0023) ATP-synt_ab; ATP synthase alpha/beta family, nucleotide-binding domain (PF00006; HMM-score: 225.8)
    and 17 more
    HAS-barrel (CL0275) ATP-synt_ab_N; ATP synthase alpha/beta family, beta-barrel domain (PF02874; HMM-score: 75.9)
    P-loop_NTPase (CL0023) RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 23.3)
    no clan defined T3SS_ATPase_C; T3SS EscN ATPase C-terminal domain (PF18269; HMM-score: 18.1)
    P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 17.4)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 16.4)
    NACHT; NACHT domain (PF05729; HMM-score: 15.1)
    AAA_25; AAA domain (PF13481; HMM-score: 14.8)
    ATPase; KaiC (PF06745; HMM-score: 14.6)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 14.5)
    ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 14.3)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 13.9)
    AAA_19; AAA domain (PF13245; HMM-score: 13.5)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 12.5)
    EFTPs (CL0575) Gar1; Gar1/Naf1 RNA binding region (PF04410; HMM-score: 11.9)
    P-loop_NTPase (CL0023) AAA_30; AAA domain (PF13604; HMM-score: 11.9)
    AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 11.4)
    TrwB_AAD_bind; Type IV secretion-system coupling protein DNA-binding domain (PF10412; HMM-score: 10.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016507
    • TAT(Tat/SPI): 0.000328
    • LIPO(Sec/SPII): 0.011972
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000094354 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIVLEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDLEAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVGKTVLIQELIHNIAQEHGGISVFAGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEPPGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQPTLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQLGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDEEKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAFRGVGSIEDVIAKAEKMGF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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