From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 20-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC_RS00805 [old locus tag: SPNOXC01420 ]
  • pan locus tag?: PNEUPAN000791000
  • symbol: SPNOXC_RS00805
  • pan gene symbol?: argG
  • synonym:
  • product: argininosuccinate synthase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC_RS00805 [old locus tag: SPNOXC01420 ]
  • symbol: SPNOXC_RS00805
  • product: argininosuccinate synthase
  • replicon: chromosome
  • strand: +
  • coordinates: 142403..142873
  • length: 471
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_017592 (142403..142873) NCBI
  • BioCyc: SPNOXC_RS00805 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    TTGAGGATGCCTTTAAAGCGTCCATTGAAAAATAGAAAGAAGGAAAAGAACATGAGTAAA
    GAAAAAGTAATTTTGGCCTATTCTGGCGGTTTGGACACATCAGTTGCTATTACCTGGTTA
    AAGAAAGACTATGATGTTGTTTCAGTTTGTATGGATGTGGGTGAAGGGAAAGACTTAGAC
    TTCATCCATGATAAGGCTCTCAAGGTTGGGGCAGTCGAATCTTATGTCATTGATGTCAAG
    GACGAATTTGCTACAGATTATGTGCTAGTGGCTCTTCAGTCACATGCCTATTATGAACAA
    AAGTACCCCTTGGTATCTGCCTTGAGCCGCCCTCTTATTTCTAAAAAATTAGTTGAAATA
    GCGCATCAGACAGGAGCGACTACAATTGCTCATGGCTGTACCGGTAAGGGGAATGACCAA
    GTCGAATACCAGATTGCAGTCGCTAAGAAAGCGAATGAAGCTAAAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    471

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC_RS00805 [old locus tag: SPNOXC01420 ]
  • symbol: SPNOXC_RS00805
  • description: argininosuccinate synthase
  • length: 156
  • theoretical pI: 9.44352
  • theoretical MW: 17347
  • GRAVY: -0.319231

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Amino acid biosynthesis Glutamate family argininosuccinate synthase (TIGR00032; EC 6.3.4.5; HMM-score: 174.4)
    and 4 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis GMP synthase (glutamine-hydrolyzing), C-terminal domain (TIGR00884; EC 6.3.5.2; HMM-score: 14.7)
    Hypothetical proteins Conserved TIGR00268 family protein (TIGR00268; HMM-score: 14.4)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase (TIGR00420; EC 2.1.1.61; HMM-score: 14)
    Unknown function General queuosine biosynthesis protein QueC (TIGR00364; HMM-score: 12.5)
  • TheSEED: see SPNOXC01420
  • ⊞PFAM:
    HUP (CL0039) Arginosuc_synth; Arginosuccinate synthase (PF00764; HMM-score: 186.1)
    and 3 more
    tRNA_Me_trans; tRNA methyl transferase HUP domain (PF03054; HMM-score: 16.5)
    QueC; Queuosine biosynthesis protein QueC (PF06508; HMM-score: 14.3)
    Diphthami_syn_2; Diphthamide synthase (PF01902; HMM-score: 13.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011922
    • TAT(Tat/SPI): 0.000299
    • LIPO(Sec/SPII): 0.0012
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_096001214 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRMPLKRPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDYDVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKYPLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNOXC_RS00805&oldid=118185"