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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 19-NOV-2015
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae A66
- locus tag: A66_00063 [new locus tag: A66_RS00330 ]
- pan locus tag?: PNEUPAN000699000
- symbol: A66_00063
- pan gene symbol?: purE
- synonym:
- product: Phosphoribosylaminoimidazole carboxylase catalytic subunit
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: A66_00063 [new locus tag: A66_RS00330 ]
- symbol: A66_00063
- product: Phosphoribosylaminoimidazole carboxylase catalytic subunit
- replicon: chromosome
- strand: +
- coordinates: 59981..60502
- length: 522
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: LN847353 (59981..60502) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0059 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
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241
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421
481GTGATTGTTGAAAAAGAGGAAAAAGGAGAAGAAATGAAACCAGTAATTTCCATCATCATG
GGCTCAAAATCCGACTGGGCAACCATGCAAAAAACAGCAGAAGGCCTAGACCGCTTCGGT
GTAGCCTACGAAAAGAAAGTTGTTTCCGCACACCGTACACCAGACCTCATGTTCAGATAT
GCCGAAGAAGCTCGTAGCCGTGGCATCAAGGTCATTATCGCAGGTGCTGGTGGTGCCGCG
CATTTGCCAGGCATGGTAGCTGCCAAAACAACCCTTCCTGTCATAGGGGTACCTGTCAAG
TCTCGTGCTCTTAGCGGTGTGGACTCGCTCTACTCTATCGTACAGATGCCGGGTGGGGTG
CCAGTTGCGACAATGGCTATCGGTGAAGCTGGAGCGACTAACGCAGCTCTCTTTGCCCTC
CGTCTCCTCTCTGTAGAAGATAAGTCCATTGCGGATGCACTTGCCAACTTTGCTGAAGAA
CAAGGAAAAATCGCAGAGGAGTCTACAAATGAGCTCATCTAA60
120
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522
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: A66_00063 [new locus tag: A66_RS00330 ]
- symbol: A66_00063
- description: Phosphoribosylaminoimidazole carboxylase catalytic subunit
- length: 173
- theoretical pI: 5.32841
- theoretical MW: 18260
- GRAVY: 0.105202
⊟Function[edit | edit source]
- reaction: EC 4.1.1.21? ExPASyPhosphoribosylaminoimidazole carboxylase 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO2
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylaminoimidazole carboxylase, catalytic subunit (TIGR01162; EC 4.1.1.21; HMM-score: 217.7)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: DHQS (CL0224) AIRC; AIR carboxylase (PF00731; HMM-score: 214.3)and 1 moreFe-ADH_2; Iron-containing alcohol dehydrogenase (PF13685; HMM-score: 17)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: unknown (no significant prediction)
- Cytoplasmic Score: 2.5
- Cytoplasmic Membrane Score: 2.5
- Cellwall Score: 2.5
- Extracellular Score: 2.5
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006013
- TAT(Tat/SPI): 0.000817
- LIPO(Sec/SPII): 0.002161
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: CRI60774 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MIVEKEEKGEEMKPVISIIMGSKSDWATMQKTAEGLDRFGVAYEKKVVSAHRTPDLMFRYAEEARSRGIKVIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSIVQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESTNELI
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- data available for TIGR4
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0059 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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