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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-SEP-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: ASP0581_10760 [new locus tag: EL334_RS05725 ]
  • pan locus tag?: PNEUPAN000854000
  • symbol: ASP0581_10760
  • pan gene symbol?: orf21
  • synonym:
  • product: cell division protein FtsK

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_10760 [new locus tag: EL334_RS05725 ]
  • symbol: ASP0581_10760
  • product: cell division protein FtsK
  • replicon: chromosome
  • strand: +
  • coordinates: 1073099..1074376
  • length: 1278
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AP019192 (1073099..1074376) NCBI
  • BioCyc: see EL334_RS05725
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    GTGAAGACAATCCAGCAGATCAACTGGCAGGATTTTAACCTATCACAAGCAGATAAGATT
    GACATTCCCTATTTAATTATCAGTTTCAGTGTCGCAATTCTTATCTGCTTGCTGGTAGCG
    TTTGTATTCAAACGGGTTCGCTATGATACGGTTAAACAACTTTACCACCGTCAAAAACTG
    GCAAAGATGATACTTGAAAACAAGTGGTATGAATCTGAACAGGTCAAAACAGAGGGTTTC
    TTTAAAGATAGTGCTGGTCGTACAAAGGAAAAGATAACCTACTTCCCTAAAATGTATTAT
    CGACTTAAAAATGGCTTGATACAGATACGGGTGGAAATCACGCTGGGAAAATATCAAGAC
    CAACTCTTACACTTGGAAAAGAAATTAGAGAGTGGCTTGTACTGTGAGCTGACGGATAAA
    GAGTTAAAGGATTCCTATGTGGAATATACTTTGCTCTATGACACCATAGCCAGTCGTATT
    TCTATTGATGAAGTAGAAGCTAAAGATGGTAAACTTCGCTTAATGAAAAACGTATGGTGG
    GAATATGATAAGCTCCCTCATATGTTGATTGCTGGTGGTACAGGTGGCGGTAAAACTTAC
    TTTATACTGACACTGATTGAAGCCTTGCTTCATACAGATTCAAAACTGTATATTCTTGAC
    CCGAAAAATGCTGATCTTGCGGACTTAGGTTCTGTGATGGCAAATGTCTACTATAGAAAA
    GAAGACTTGCTTTCTTGCATTGAAACATTCTATGAAGAAATGATGAAACGTAGTGAGGAA
    ATGAAGCAGATGAAGAACTATAAGACTGGCAAAAATTATGCTTACTTAGGTCTCCCGGCA
    CACTTCTTAATCTTTGATGAATACGTCGCTTTCATGGAAATGCTGGGAACAAAAGAAAAC
    ACCGCAGTTATGAATAAGCTGAAACAGATTGTCATGTTAGGTCGTCAAGCTGGCTTCTTT
    CTAATACTGGCTTGTCAACGTCCAGACGCAAAATATTTAGGCGACGGAATCCGTGATCAG
    TTTAATTTCAGAGTGGCTTTAGGTCGTATGTCTGAAATGGGCTATGGCATGATGTTTGGC
    AGTGACGTACAAAAGGATTTCTTCTTAAAGCGAATCAAAGGTCGTGGCTATGTTGATGTA
    GGAACAAGTGTCATATCAGAGTTTTATACTCCCCTTGTACCAAAAGGATATGATTTCTTG
    GAGGAAATTAAAAAGTTATCCAACAGCAGACAGTCCACGCAGGCGACGTGCGAAGCGGAA
    GTCGCAGGTGTGGACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1278

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ASP0581_10760 [new locus tag: EL334_RS05725 ]
  • symbol: ASP0581_10760
  • description: cell division protein FtsK
  • length: 425
  • theoretical pI: 8.35445
  • theoretical MW: 49298
  • GRAVY: -0.242118

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCa (TIGR03924; HMM-score: 42.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EssC (TIGR03928; HMM-score: 38.3)
    and 4 more
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 27.5)
    Genetic information processing Mobile and extrachromosomal element functions Other conjugative coupling factor TraD, SXT/TOL subfamily (TIGR03743; HMM-score: 20)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair putative DnaQ family exonuclease/DinG family helicase (TIGR01407; HMM-score: 13.9)
    type IV conjugative transfer system coupling protein TraD (TIGR02759; HMM-score: 13.9)
  • TheSEED:
  • PFAM:
    P-loop_NTPase (CL0023) FtsK_SpoIIIE; FtsK/SpoIIIE family (PF01580; HMM-score: 36.9)
    and 9 more
    DUF87; Helicase HerA, central domain (PF01935; HMM-score: 25.1)
    AAA_10; AAA-like domain (PF12846; HMM-score: 18)
    ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 17.4)
    TrwB_AAD_bind; Type IV secretion-system coupling protein DNA-binding domain (PF10412; HMM-score: 16.9)
    AAA; ATPase family associated with various cellular activities (AAA) (PF00004; HMM-score: 15)
    AAA_19; AAA domain (PF13245; HMM-score: 14.2)
    Pox_A32; Poxvirus A32 protein (PF04665; HMM-score: 14.1)
    AAA_22; AAA domain (PF13401; HMM-score: 12.7)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0004
    • Cytoplasmic Membrane Score: 0.9904
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0091
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002083
    • TAT(Tat/SPI): 0.000168
    • LIPO(Sec/SPII): 0.00133
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG81598 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKTIQQINWQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILENKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLHLEKKLESGLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEYDKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRKEDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTKENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYGMMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQATCEAEVAGVD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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