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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7465
  • locus tag: AT689_RS08420 [old locus tag: ERS445053_01651 ]
  • pan locus tag?: PNEUPAN000746000
  • symbol: AT689_RS08420
  • pan gene symbol?: —
  • synonym:
  • product: ISL3 family transposase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: AT689_RS08420 [old locus tag: ERS445053_01651 ]
  • symbol: AT689_RS08420
  • product: ISL3 family transposase
  • replicon: chromosome
  • strand: +
  • coordinates: 1593644..1594873
  • length: 1230
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LN831051 (1593644..1594873) NCBI
  • BioCyc: AT689_RS08420 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0966 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGGAACAATTACATTTTATCACAAAATTACTAGACATTAAAGACCCTAATATCCAGATT
    TTAGACATCATCAATAAGGATACACACAAGGAAATCATCGCCAAACTGGACTATGAAGCT
    CCATCTTGTCCTGAGTGCGGAAGTCAAATGAAGAAATATGACTTTCAAAAACCTTCTAAA
    ATTCCTTATCTTGAAACAACTGGTATGCCTACTAGAATTCTCCTTAGAAAGCGTCGTTTC
    AAGTGCTATCATTGTTCTAAAATGATGGTCGCTGAAACTTCTATCGTCAAGAAGAATCAC
    CAAATCCCTCGTATCATCAACCAAAAGATTGCTCAAAAGTTAATTGAAAAGATTTCTATG
    ACTGATATTGCCCATCAGCTTTCCATCTCAACTTCAACTGTTATTCGTAAGCTCAATGAT
    TTTCACTTTAAACATGATTTTTCTTGTCTTCCTGAGATTATGTCTTGGGATGAGTATGCT
    TTTACAAAGGGAAAGATGAGCTTCATTGCGCAAGATTTTAACAATCTCAATATCATCACT
    GTTCTTGAGGGAAGAACACAAGCTATCATTCGAAATCACTTTCTTCGCTACGATAGAGTT
    GTCCGATGTCGCGTCAAAATTATTACTATGGATATGTTTAGCCCTTACTATGGCTTGGCT
    AAACAGCTTCGCTTTCACATTGTACAACATCTTAGCCGTGCTATGAGTCGTGTGCGTGTT
    CAAATCATGAATCAGTTTCATCGAAAATTCCATGAATACAAGGCTATCAAGCGCTACTGG
    AAGCTCATACAACAGGATAGCCGTAAACTGAGTGATAAGCGATTTTATCGTCCTACTTTT
    CGTATACATTTAACCAATAAAGAGATTTTAGACAAGCTTTTGAGCTATTCACAAGACTTG
    AAACATCACTATCAGCTCTATCAACTCTTGCTTTTTCACTTCCAGAATAAGGAACCAGAG
    AAATTTTTCGGGCTTATTGAGGACAATCTTAAGCAGGTTCATCCTATTTTTCAGACTGTC
    TTTAAAACCTTCCTCAAAGATAAAGAAAAGATTGTCAACGCCCTTCAACTACACTATTCT
    AATGCCAAACTGGAAGCGACCAATAATCTCATCAAACTTATCAAGCGCAATGCCTTTGGT
    TTTCGAAACTTTGAAAACTTCAAAAAACGGATTTTTATCGCTCTGAATATCAAAAAAGAA
    AGGACAAAATTTGTCCTTTCTCGAGCTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1230

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: AT689_RS08420 [old locus tag: ERS445053_01651 ]
  • symbol: AT689_RS08420
  • description: ISL3 family transposase
  • length: 409
  • theoretical pI: 10.5739
  • theoretical MW: 49068.4
  • GRAVY: -0.433252

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for TIGR4
  • PFAM:
    RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 131.3)
    and 14 more
    Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 47.1)
    HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 36.3)
    Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 19.8)
    HTH (CL0123) HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 15.3)
    HTH_AsnC-type; AsnC-type helix-turn-helix domain (PF13404; HMM-score: 14.9)
    HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.3)
    no clan defined FTO_CTD; FTO C-terminal domain (PF12934; HMM-score: 13.4)
    HTH (CL0123) HTH_11; HTH domain (PF08279; HMM-score: 13.3)
    no clan defined DUF6431; Domain of unknown function (DUF6431) (PF20020; HMM-score: 13.3)
    HTH (CL0123) HTH_23; Homeodomain-like domain (PF13384; HMM-score: 12.9)
    HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.5)
    Zn_Beta_Ribbon (CL0167) DZR; Double zinc ribbon (PF12773; HMM-score: 12.3)
    no clan defined YdjO; Cold-inducible protein YdjO (PF14169; HMM-score: 10.7)
    HTH (CL0123) HTH_6; Helix-turn-helix domain, rpiR family (PF01418; HMM-score: 8.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.6975
    • Cytoplasmic Membrane Score: 0.0038
    • Cell wall & surface Score: 0.0223
    • Extracellular Score: 0.2763
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.026575
    • TAT(Tat/SPI): 0.000275
    • LIPO(Sec/SPII): 0.000789
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000436532 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MEQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYEAPSCPECGSQMKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLEGRTQAIIRNHFLRYDRVVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSRAMSRVRVQIMNQFHRKFHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRIHLTNKEILDKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPIFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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