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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 09-DEC-2016
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae SP49
- locus tag: BMJ42_00397 [new locus tag: BMJ42_RS02095 ]
- pan locus tag?: PNEUPAN001018000
- symbol: rsuA1
- pan gene symbol?: rsuA-1
- synonym:
- product: ribosomal small subunit pseudouridine synthase A
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: BMJ42_00397 [new locus tag: BMJ42_RS02095 ]
- symbol: rsuA1
- product: ribosomal small subunit pseudouridine synthase A
- replicon: chromosome
- strand: +
- coordinates: 341883..342605
- length: 723
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP018136 (341883..342605) NCBI
- BioCyc: see BMJ42_RS02095
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0260 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
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361
421
481
541
601
661
721ATGAGATTAGATAAATTTTTAGTTGCCTGTGCGGTGGGAAGTCGGACTGAGGTCAAAAAC
TTGCTCAAGGCTGGGCGCGTGACTGTAAATGGTAAAAAAGAAAAATCAGCTAAATTGCAG
ATTGATGAAAAAATAGATGAGATTCGCTTTGATGGGCAAGTGTTGGAGTATGAAGAGTTT
GTCTACTACATGATGAACAAGCCCAAAGGAGTTATCTCAGCGACTGAGGATCCCAAGCAC
AGAACCGTTCTGGACTTGTTGGATGACTTGGCGCGGAGTAAGGAAGTTTTCCCAGTAGGA
CGCTTGGATATTGACACGCATGGTCTTTTGCTCTTGACCAATGATGGTCAGCTGGCTCAT
GTTCTTCTTTCGCCCAAGCGTCATGTGGACAAGACTTATCTGGCACAAGTCAAGGGAATT
ATGACCCAAGAAGATGTGGAGACATTTATCAAGGGCATTCCGCTCAAAGACTTTACCTGT
CAGCCCGCTAGACTGGAGATTCTTTCCACAGATGCAGAAAAGAATCAGAGCCAAATCCGT
GTGACCATTGCAGAAGGGAAGTTTCATCAGATCAAGCGTATGGTGGGCTACTGTGGCAAG
GAAGTGGTGGACTTGCAACGATTGACTATGGGAACTTTAGTATTAGATGAGAACCTGGAA
CGAGGGGAATGGCGTCGCTTGACCAAGGAAGAATTAGAAATTCTCCGCGCTAATATTATT
TAA60
120
180
240
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420
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540
600
660
720
723
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: BMJ42_00397 [new locus tag: BMJ42_RS02095 ]
- symbol: RsuA1
- description: ribosomal small subunit pseudouridine synthase A
- length: 240
- theoretical pI: 7.55539
- theoretical MW: 27391.6
- GRAVY: -0.3325
⊟Function[edit | edit source]
- reaction: EC 4.2.1.70? ExPASyPseudouridylate synthase Uracil + D-ribose 5-phosphate = pseudouridine 5'-phosphate + H2O
- TIGRFAM: Protein synthesis tRNA and rRNA base modification pseudouridine synthase (TIGR00093; EC 5.4.99.-; HMM-score: 171)and 3 moreProtein synthesis tRNA and rRNA base modification pseudouridine synthase, RluA family (TIGR00005; EC 5.4.99.-; HMM-score: 49.1)Protein synthesis tRNA and rRNA base modification pseudouridine synthase Rlu family protein, TIGR01621 (TIGR01621; EC 5.4.99.-; HMM-score: 22)Unknown function General TlyA family rRNA methyltransferase/putative hemolysin (TIGR00478; HMM-score: 16.4)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: PseudoU_synth (CL0649) PseudoU_synth_2; RNA pseudouridylate synthase (PF00849; HMM-score: 76.8)and 2 moreS4 (CL0492) S4; S4 domain (PF01479; HMM-score: 34)S4_2; S4 domain (PF13275; HMM-score: 15.7)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9882
- Cytoplasmic Membrane Score: 0.0103
- Cell wall & surface Score: 0.0013
- Extracellular Score: 0.0002
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.041039
- TAT(Tat/SPI): 0.009279
- LIPO(Sec/SPII): 0.013158
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: APJ29733 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEKIDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRLDIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFIKGIPLKDFTCQPARLEILSTDAEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDENLERGEWRRLTKEELEILRANII
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0260 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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