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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SP49
  • locus tag: BMJ42_RS06445 [old locus tag: BMJ42_01209 ]
  • pan locus tag?: PNEUPAN002459000
  • symbol: BMJ42_RS06445
  • pan gene symbol?: kcsA
  • synonym:
  • product: potassium channel family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: BMJ42_RS06445 [old locus tag: BMJ42_01209 ]
  • symbol: BMJ42_RS06445
  • product: potassium channel family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1155099..1155875
  • length: 777
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP018136 (1155099..1155875) NCBI
  • BioCyc: BMJ42_RS06445 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    TTGAAGAAAAAATGGTTTTTTGCAGATTATTATGATACAACAATTATTTTACTTGCTTTA
    ATCTCTGTTATTCTGGTATTACTTGGATTTGCTGAGATGACTGATTTGGACAATCCGCCT
    TATAGTATTATTGATTTAGTAATCTGGGGTGTTTTTGTAATTGATTATAGTTGGCGCTTT
    TTTATTACTAAAAGAAAATGGCGCTTTATTCTTGAAAATATTTTTGATTTATTGACCATT
    CTCCCTTTAAATGCTATTTTTACAGTGTTTCGATTAGGACGTATCTTCCGCTTAGCAAGG
    CTGACAAAATTACTGAAACTGACTCGTTTACTTAGAATAATTGGACTTACAGGTAAACTA
    GAAAGAAAAATTAGTAGATTCTTACGAACAAATGGATTGATTTATATCTTGTATGTTAAT
    ATCTTTATTGTTCTAGTAGGGAGTTCGATTTTATCCGTTGTTGAAGAAAAATCCTTCTCA
    GATAGTCTTTGGTGGGCTCTTGTGACAGTAACTACTGTTGGTTATGGTGATATTGTTCCA
    GTTTCCCTTTTTGGGAAATGGCTAGCAGTTTTACTGATGCTTGTCGGTATTGGAACAATA
    GGGATGCTAACAAGTGCTTTGACGAACTTTTTTGTAAAGGATAATCCAGATGAACAGATA
    AAACTTGATAAACTCAAAGACGAATTATCGAGCCAAAGAATATTAATAGAGAAACAATCT
    GAAAAAATCGAAGAACTACATCGAATGATAAAAGACTTAGTTGAAAAAATATCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    777

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: BMJ42_RS06445 [old locus tag: BMJ42_01209 ]
  • symbol: BMJ42_RS06445
  • description: potassium channel family protein
  • length: 258
  • theoretical pI: 10.0312
  • theoretical MW: 29887.5
  • GRAVY: 0.540698

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    Ion_channel (CL0030) Ion_trans_2; Ion channel (PF07885; HMM-score: 63.2)
    Ion_trans; Ion transport protein (PF00520; HMM-score: 57.4)
    and 6 more
    Lig_chan; Ligand-gated ion channel (PF00060; HMM-score: 14.4)
    no clan defined Sec2p; GDP/GTP exchange factor Sec2p (PF06428; HMM-score: 13.9)
    TBCA; Tubulin binding cofactor A (PF02970; HMM-score: 13.6)
    DUF979; Protein of unknown function (DUF979) (PF06166; HMM-score: 12.4)
    CNNM; Cyclin M transmembrane N-terminal domain (PF01595; HMM-score: 8)
    Holin_SPP1; SPP1 phage holin (PF04688; HMM-score: 7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 5
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9997
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0002
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.060578
    • TAT(Tat/SPI): 0.000311
    • LIPO(Sec/SPII): 0.027182
  • predicted transmembrane helices (TMHMM): 5

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000731138 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKKWFFADYYDTTIILLALISVILVLLGFAEMTDLDNPPYSIIDLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLTILPLNAIFTVFRLGRIFRLARLTKLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFSDSLWWALVTVTTVGYGDIVPVSLFGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDEQIKLDKLKDELSSQRILIEKQSEKIEELHRMIKDLVEKIS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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