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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SP49
  • locus tag: BMJ42_RS07810 [old locus tag: BMJ42_01475 ]
  • pan locus tag?: PNEUPAN002806000
  • symbol: BMJ42_RS07810
  • pan gene symbol?: snf
  • synonym:
  • product: DEAD/DEAH box helicase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: BMJ42_RS07810 [old locus tag: BMJ42_01475 ]
  • symbol: BMJ42_RS07810
  • product: DEAD/DEAH box helicase
  • replicon: chromosome
  • strand: -
  • coordinates: 1402196..1405294
  • length: 3099
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP018136 (1402196..1405294) NCBI
  • BioCyc: BMJ42_RS07810 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1351 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    ATGGCTAAATTGATTCCGGGGAAAATTCGTATCGAAGGTGTTGCCCTTTATGAAACTGGT
    AAGGTTGATATCATCAAGGAAAAGAACAATCGGCTCTACGCTCGCGTTGCAGAAGAAGAA
    CTGCGCTATAGTTTAGAGGATGATTTGATTTTTTGTGCCTGTGATTTTTTTCAAAAGAGG
    GGCTACTGTGTGCATTTGGCAGCGCTAGAGCATTTTCTGAAAAATGATGAGCGTGGTCAG
    GAAATCTTGTGGAGTCTGGAAGAAGGTCATGAAGAAAAAGAGGCTGTTGAAACCAAGGTG
    ACCTTGGGTGGCAAGTTTTTGGATCGAATTTTATCTCCAAAATCAGAATGCGCCTATGAG
    TTATCAGCTGTGGGTCAGGTGGAAGCAGGAACCAATCATATCTTGTGGACTCTGAGAATC
    GGCCAAATCAATAGCCAAAAATACTATGTCATTCGGGATATTCCACTTTTTTTAAGGATT
    GTCGAGCAGAGAAAGTCGTATATGATTGGCAAGATTTATGAGGAGTCTCTTTCTTGGGAA
    GCCTTTGATGATGCCAGCCAAGAACTTTTGACTTTCTTGCACGGACTAACGGAGGAAGGG
    CTGGTTCCAGACCTCTTTTTCCAAAACCAAGGTCGGCACCTCTTTTTCCCTCTGACCTTT
    TTTGAGCAGGGTGTGAATTTACTGATGGCCTTGCCCCATTTTCAATTTGACCATCAAGTG
    GATAGCTACCAAACCCTGCTTTTTCAGGATATGCATGCTGATGCCAATCTATTTGCCTTT
    ACAGTAACAGAATACTCGGACTATTTTGAAATGGAAATCAGTGAGAGTCCTAGGGTCAAT
    GTCTTTTATCAGGGAGTAGTACTTTTCCATAAAGGTCAGGTTTATTTTTTAACAGACCAG
    CAGATTCGTCTTCTCAAGGAAATTAAAGCGTTACCTGTGGATCGACAAGGAAAGAAATAC
    CTGCAATTTGATAGCAGTGATCGAGACAAATTGGCCTCCTGTCTGACTCTTTTTATCCAG
    ATGGGCACCGTTTCAGCTCCAGAACGTCTACAAATCAAAACTTTTGCGCCCTCTTTTTAC
    TTTGACAGGGAAGAAGATAATCGGATTCGTTTAGAAATTCAGTTTGATTATGGAAATAGA
    CAGGTATCTAGCCGACAAGAGCTAGAAGAATTACCATTTTCAAGTGACGTGGACTTAGAA
    GAAAGAATTTTCCAAGTCTGTTTGGCTGCGGGCTTTGAAGCCGATTTTCAATCTTGGCGT
    CAGGCCTTAAAAGCGGAGTCTGTCTATCATTTTTTTCATGATATCATTCCAGTCTTTGAA
    AAACTCGGGCATGTTGACCTATCAGATAAACTGGAAGAGCTTTATAGCCTAGCGAGTCCT
    CAGGTGCAAATTGCCTCCAAGGGAGGTCTCTTGGAAATCCAGTTTGATTTTCAAGATATT
    GCCCAGGAGGAAATCGACCAAGCCATGCAGGCCTTGGTTGCCAATCAGGATTTTTATATT
    GATTCGTCTAATCAAGTTTACTTTTTCGATGAAGAAACCAAGAAAATTCGGCAAAATCTA
    CAGGAACTGGGGCAATTTGAATTAAAAGATGGGACCTTGCAGGCTCGGAAATCCTTGGCC
    TACAGTTTAGCTCATCTCTTTGAAGGGCGAGACCGTGTTTCTTTTTCACAAGAATTCCAG
    AATCTGGCCCAGGATTTGACGCATCCAGAGGACTTTCCTTTGCAAGCAACTCAGGTCAAG
    GCTGACTTGCGAGATTATCAGGAAAAGGGAATTGGCTGGTTGCAGATGCTCCATCATTAT
    GGTTTTGGTGGGATTTTGGCTGATGATATGGGACTTGGGAAAACCCTTCAGACCATTGCT
    TTTTTGACTAGTCAAGTGACAAAAGAAAGTCGAGTCTTGATTCTCGCTCCGTCGGGTTTG
    ATTTACAACTGGGCAGATGAGTTTCAGAAATTTGCTCCACAGTTGGATGTGACTGTTGTT
    CATGGTTTGAAAGCAAGTCGTGAGGAGATTCTTGCCGAGAGCCATCAAATCTATGTGACT
    AGCTATGCCACCTTCCGTCAGGACAGTGAGTTTTATCAGGGGATGGCCTTTGACTTCCTT
    TTCTTAGATGAGGCTCAGGTCATGAAAAATGCCCAGACCAAGATTGCCCAGACCTTGAGA
    CAATTTGTGGTGCCGTCGGTCTTTGCCTTGTCAGGAACTCCGATTGAAAACCATCTGGGT
    GAGTTGTGGTCTATTTTCCAAATCGTCATGCCCGGACTTTTGCCAAGCAAGAAAGAATTT
    ATGAAATTGCCAGCAGAGCGAGTGGCTCAGTTTATCAAGCCTTTCGTGATGCGACGCAAG
    AAAGAAGAAGTTCTGACTGAATTGCCAGACTTGATTGAGGTGGTTTATAAAAATGAACTG
    GAAGACCAGCAAAAGGCTATTTACCTTGCCCAGTTACAACAGATGCGAGACCATCTGGCT
    CAAGTGTCAGAACAGGAATTTCAGCGAAGTCGTGTGGAAATTTTATCTGGTTTGATGCGC
    TTGCGTCAAATATGTGACACTCCTGCCCTGTTTATGGAAGATTATCAGGGAGCCAGCGGT
    AAACTAGATAGTCTCCGAGACCTACTGCTACAGGTGGCAGACGGCGGACACCGTGTCTTG
    ATTTTCTCTCAGTTCAAGGGAATGTTGGAAAAAATTGAACAAGAACTACCAGACTTGGGC
    CTGACTTCCTTTAAAATTACGGGTTCAACCCCATCCAAGGAAAGACAAGACATGACCAAG
    GCCTTTAACCAAGGAGAAAGAGATGCCTTTCTGATTTCCCTCAAGGCTGGTGGGGTCGGT
    CTGAACCTGACAGGTGCAGATACAGTGATCTTGGTTGACCTCTGGTGGAATCCTGCGGTG
    GAAGCGCAAGCCATTGGCCGTGCCCATCGGATGGGTCAGGAAGAAACGGTTGAGGTCTAT
    CGCTTGGTGACCAAGGGAACCATTGAAGAAAAAATTCAGGAACTCCAAGAACAAAAGAAA
    CATCTGGTGTCACAAGTATTGGACGGCACAGAGTCACGTGGTAGTCTGACCCTAGCAGAA
    ATTAGAGAAATTTTGGGAATTTCTGAAGCCAGCACTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3099

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: BMJ42_RS07810 [old locus tag: BMJ42_01475 ]
  • symbol: BMJ42_RS07810
  • description: DEAD/DEAH box helicase
  • length: 1032
  • theoretical pI: 4.70475
  • theoretical MW: 118427
  • GRAVY: -0.259787

⊟Function[edit | edit source]

  • reaction:
    EC 3.6.4.-?  ExPASy
  • TIGRFAM:
    DNA phosphorothioation system restriction enzyme (TIGR04095; HMM-score: 19.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined SNF2_assoc; Bacterial SNF2 helicase associated (PF08455; HMM-score: 204.7)
    P-loop_NTPase (CL0023) SNF2-rel_dom; SNF2-related domain (PF00176; HMM-score: 164.3)
    and 4 more
    Helicase_C; Helicase conserved C-terminal domain (PF00271; HMM-score: 76.8)
    no clan defined SWIM; SWIM zinc finger (PF04434; HMM-score: 16.1)
    P-loop_NTPase (CL0023) ERCC3_RAD25_C; ERCC3/RAD25/XPB C-terminal helicase (PF16203; HMM-score: 14.7)
    Glutaminase_I (CL0014) DUF4350; Domain of unknown function (DUF4350) (PF14258; HMM-score: 14)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8472
    • Cytoplasmic Membrane Score: 0.103
    • Cell wall & surface Score: 0.0085
    • Extracellular Score: 0.0413
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003733
    • TAT(Tat/SPI): 0.00012
    • LIPO(Sec/SPII): 0.000502
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_073177121 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYSLEDDLIFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTLGGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRIVEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPLTFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISESPRVNVFYQGVVLFHKGQVYFLTDQQIRLLKEIKALPVDRQGKKYLQFDSSDRDKLASCLTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELPFSSDVDLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDKLEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYFFDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDLTHPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTSQVTKESRVLILAPSGLIYNWADEFQKFAPQLDVTVVHGLKASREEILAESHQIYVTSYATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLGELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKNELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQGASGKLDSLRDLLLQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPSKERQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMGQEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEAST

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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