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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_02705 [new locus tag: CXP32_RS02705 ]
  • pan locus tag?: PNEUPAN000106000
  • symbol: CXP32_02705
  • pan gene symbol?: blpL
  • synonym:
  • product: immunity protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_02705 [new locus tag: CXP32_RS02705 ]
  • symbol: CXP32_02705
  • product: immunity protein
  • replicon: chromosome
  • strand: +
  • coordinates: 513529..513933
  • length: 405
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP025256 (513529..513933) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAAACTTTTCTTGCTAAAAAACGGAACATCTTCCTTGCGAGATTGTTCTTAGGTCAG
    TTGCCCTTGCTTGTTTCTACTTATCTATTTCTATCTCGTCAGTTTTTAAATTTTTCCGTA
    GTTTTCCAATTTCTTTTAGTAGTTATTAACTTGGCTTCTATTTTGGTTACTGTTTATCTC
    ACTAGGGAAATGAGGATAAGAGAGTTTGAAGATGATGATTTGGTTAGTCCTAGAACCAAT
    CAACTTATGTTCATCGGCTTGACAGGTTTTATGTCTATTATTTGTTTGTATAGAGGTATC
    ACAGCAGGAGAATCCTACCAACAAATAATCGCTTATATTGGCGCTGTTCTCTGCTTAATC
    ATCATGCTTCTGCTCATGTGGGGCTTGAAGTATTATAAAAAGTAG
    60
    120
    180
    240
    300
    360
    405

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: CXP32_02705 [new locus tag: CXP32_RS02705 ]
  • symbol: CXP32_02705
  • description: immunity protein
  • length: 134
  • theoretical pI: 10.0261
  • theoretical MW: 15593.8
  • GRAVY: 0.775373

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion integral membrane protein EccD (TIGR03920; HMM-score: 9.7)
    mobilome CxxCx(11)CxxC protein (TIGR04402; HMM-score: 8.7)
    and 1 more
    Metabolism Transport and binding proteins Other K-Cl cotransporter (TIGR00930; HMM-score: 5.2)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    no clan defined DUF2157; Predicted membrane protein (DUF2157) (PF09925; HMM-score: 13.2)
    and 4 more
    Cupin (CL0029) Popeye; Popeye protein conserved region (PF04831; HMM-score: 10.2)
    no clan defined ETRAMP; Malarial early transcribed membrane protein (ETRAMP) (PF09716; HMM-score: 9.8)
    DUF4199; Protein of unknown function (DUF4199) (PF13858; HMM-score: 9.7)
    Tetraspannin (CL0347) Tetraspanin; Tetraspanin family (PF00335; HMM-score: 9.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.9982
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0016
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004145
    • TAT(Tat/SPI): 0.003084
    • LIPO(Sec/SPII): 0.010623
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AUF84396 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQFLLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYIGAVLCLIIMLLLMWGLKYYKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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