PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 17-DEC-2017

⊟Summary

• organism: Streptococcus pneumoniae Xen35
• locus tag: CXP32_05665 [new locus tag: CXP32_RS05665 ]
• pan locus tag^?: PNEUPAN002276000
• symbol: CXP32_05665
• pan gene symbol^?: —
• synonym:
• product: GTP-binding protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: CXP32_05665 [new locus tag: CXP32_RS05665 ]
• symbol: CXP32_05665
• product: GTP-binding protein
• replicon: chromosome
• strand: +
• coordinates: 1068083..1068967
• length: 885
• essential: unknown

⊟Accession numbers

• Location: CP025256 (1068083..1068967) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGAAATCATTACAATCTAGTTTAGGAAATATTGAGACATTTAAACTAGACGAATTGTGT
  CCTAAGCATGAAATACAGCTAACACAAATCAAAGGAGAAAGACATGTAGTAGTGGGGTGG
  AATGAGAACGGAGAGGCAATAAAAGAAGTTCGCTGTATCCCACCCTATTGTGAACAATGC
  CAAGAAGAACAGAAAAAGCAAGATGAAGAAGATGCGATTGCTGATAATTTGAATGCTAAA
  CTATATATGCAAACTTATAATGTGTTGATGAGCAATAAGAGCTATGTAGCAGATGAGTTT
  AAAACTAAAACTTTTGATGATTTTAATGCTGTAACATCAGAAGAAAAGCGATTTTTAGAA
  TTTGCAAAAGGTCAGGTACAAAAATATCTTGATGGCATGAGGGGAAATACGCTTATCACA
  GGAGGTACAGGGATTGGAAAAACACTTTTATCAGTTGCTATTGCCAAAGGTATAAATGAG
  GGGTATAAGACAAAAGGAGAACCTAAGAGTGTGCTTTTTGTAAGCCTAACCGAAATGATC
  AAACAAATTAAAGAGGGGTGGAATTATGGTAAAGGTGCAACACTTACAGAGTTTGAAGCT
  ACTGAACTCATGAAGTCTGTTGATTACTTAATTATTGATGATTTAGGAGCAAAAAATGCT
  GTTATTAAGCCTAAGAGTGACTGGGAGCAGGATTTACTCTTTGACGTGCTAAACAATCGT
  GAAAATACCATTTTTAATACCAACCTAGATAGTGATGAGCTTAAGATAGTTTACAATGAG
  CGGAATTATAGCCGTATTCTAAAAGGACTTGAGGGTAACACTTTTAAGGCGTTTGGCATC
  AAATATAAGCGGTACTCACTCAATCAGTTAAAGAGTAATATGTGA
  60
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  885
  

⊟Protein

⊟General

• locus tag: CXP32_05665 [new locus tag: CXP32_RS05665 ]
• symbol: CXP32_05665
• description: GTP-binding protein
• length: 294
• theoretical pI: 5.33366
• theoretical MW: 33499.9
• GRAVY: -0.564626

⊟Function

• TIGRFAM:
  Genetic information processing DNA metabolism DNA replication, recombination, and repair chromosomal replication initiator protein DnaA (TIGR00362; HMM-score: 30.3)
  and 5 more
  Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides ATP-dependent Clp protease, ATP-binding subunit ClpX (TIGR00382; HMM-score: 12.5)
  Genetic information processing Protein fate Protein folding and stabilization ATP-dependent Clp protease, ATP-binding subunit ClpX (TIGR00382; HMM-score: 12.5)
  Cellular processes Cellular processes Conjugation P-type conjugative transfer ATPase TrbB (TIGR02782; HMM-score: 11.9)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair orc1/cdc6 family replication initiation protein (TIGR02928; HMM-score: 11.8)
  helicase/secretion neighborhood ATPase (TIGR03819; HMM-score: 10.3)
• TheSEED: data available for TIGR4
• PFAM:
  P-loop_NTPase (CL0023) IstB_IS21; IstB-like ATP binding protein (PF01695; HMM-score: 37.2)
  and 11 more
  Bac_DnaA; Bacterial dnaA protein (PF00308; HMM-score: 21.9)
  ATPase; KaiC (PF06745; HMM-score: 21.4)
  T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 19.4)
  DEAD; DEAD/DEAH box helicase (PF00270; HMM-score: 17.5)
  ResIII; Type III restriction enzyme, res subunit (PF04851; HMM-score: 17.4)
  NACHT; NACHT domain (PF05729; HMM-score: 17.1)
  AAA_22; AAA domain (PF13401; HMM-score: 15.8)
  AAA_19; AAA domain (PF13245; HMM-score: 14.2)
  DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 13.6)
  Kinesin; Kinesin motor domain (PF00225; HMM-score: 12.5)
  RNA_helicase; RNA helicase (PF00910; HMM-score: 11.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8947
  • Cytoplasmic Membrane Score: 0.048
  • Cell wall & surface Score: 0.0007
  • Extracellular Score: 0.0566
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.014242
  • TAT(Tat/SPI): 0.000263
  • LIPO(Sec/SPII): 0.000968
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: AUF84906 NCBI
• UniProt:

⊟Protein sequence

• MKSLQSSLGNIETFKLDELCPKHEIQLTQIKGERHVVVGWNENGEAIKEVRCIPPYCEQCQEEQKKQDEEDAIADNLNAKLYMQTYNVLMSNKSYVADEFKTKTFDDFNAVTSEEKRFLEFAKGQVQKYLDGMRGNTLITGGTGIGKTLLSVAIAKGINEGYKTKGEPKSVLFVSLTEMIKQIKEGWNYGKGATLTEFEATELMKSVDYLIIDDLGAKNAVIKPKSDWEQDLLFDVLNNRENTIFNTNLDSDELKIVYNERNYSRILKGLEGNTFKAFGIKYKRYSLNQLKSNM

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications