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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-FEB-2021

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_RS03650 [old locus tag: CXP32_03650 ]
  • pan locus tag?: PNEUPAN001679000
  • symbol: CXP32_RS03650
  • pan gene symbol?:
  • synonym:
  • product: lactoylglutathione lyase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_RS03650 [old locus tag: CXP32_03650 ]
  • symbol: CXP32_RS03650
  • product: lactoylglutathione lyase
  • replicon: chromosome
  • strand: +
  • coordinates: 696747..697094
  • length: 348
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_CP025256 (696747..697094) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0637 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    ATGAATTTAAATCAATTAGATATTATCGTTTCAAATGTTCCCCAAGTCTGTGCTGACTTG
    GAGCATATCTTGGATAAAAAGGCAGATTATGCTAATGATGGTTTTGCTCAGTTTACGATT
    GGTAGTCACTGCCTTATGTTGTCACAAAATCATTTGGTTCCTTTGGAAAACTTTCAGTCA
    GGAATCATTATTCATATCGAGGTTGAGGATGTAGACCAGAACTACAAACGGTTGAACGAG
    CTTGGTATAAAGGTTTTACACGGACCAACTGTAACCGATTGGGGAACAGAGTCCTTATTA
    GTTCAAGGACCTGCTGGTCTAGTGCTTGATTTTTATCGTATGAAATAG
    60
    120
    180
    240
    300
    348

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_RS03650 [old locus tag: CXP32_03650 ]
  • symbol: CXP32_RS03650
  • description: lactoylglutathione lyase
  • length: 115
  • theoretical pI: 4.59421
  • theoretical MW: 12888.7
  • GRAVY: -0.0026087

Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Other lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 12.5)
    Metabolism Central intermediary metabolism Amino sugars lactoylglutathione lyase (TIGR00068; EC 4.4.1.5; HMM-score: 12.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Glyoxalase (CL0104) Glyoxalase_2; Glyoxalase-like domain (PF12681; HMM-score: 17)
    Glyoxalase; Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily (PF00903; HMM-score: 16.8)
    Glyoxalase_3; Glyoxalase-like domain (PF13468; HMM-score: 15.5)
    and 1 more
    Glyoxalase_6; Glyoxalase-like domain (PF18029; HMM-score: 12.5)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003731
    • TAT(Tat/SPI): 0.000174
    • LIPO(Sec/SPII): 0.000879
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001052657 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNLNQLDIIVSNVPQVCADLEHILDKKADYANDGFAQFTIGSHCLMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQGPAGLVLDFYRMK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]