From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 19-APR-2025

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae Xen35
  • locus tag: CXP32_RS09750 [old locus tag: CXP32_09750 ]
  • pan locus tag?: PNEUPAN003516000
  • symbol: CXP32_RS09750
  • pan gene symbol?:
  • synonym:
  • product: alkanal monooxygenase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: CXP32_RS09750 [old locus tag: CXP32_09750 ]
  • symbol: CXP32_RS09750
  • product: alkanal monooxygenase
  • replicon: chromosome
  • strand: -
  • coordinates: 1832767..1833849
  • length: 1083
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_CP025256 (1832767..1833849) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAAATTTGGAAACTTTTTGCTTACATACCAACCTCCCCAATTTTCTCAAACAGAGGTA
    ATGAAACGTTTGGTTAAATTAGGTCGCATCTCTGAGGAGTGTGGTTTTGATACCGTATGG
    TTACTGGAGCATCATTTCACGGAGTTTGGTTTGCTTGGTAACCCTTATGTCGCTGCTGCA
    TATTTACTTGGCGCGACTAAAAAATTGAATGTAGGAACTGCCGCTATTGTTCTTCCCACA
    GCCCATCCAGTACGCCAACTTGAAGATGTGAATTTATTGGATCAAATGTCAAAAGGACGA
    TTTCGGTTTGGTATTTGCCGAGGGCTTTACAACAAGGACTTTCGCGTATTCGGCACAGAT
    ATGAATAACAGTCGCGCCTTAGCGGAATGCTGGTACGGGCTGATAAAGAATGGCATGACA
    GAGGGATATATGGAAGCTGATAATGAACATATCAAGTTCCATAAGGTAAAAGTAAACCCC
    GCGGCGTATAGCAGAGGTGGCGCACCGGTTTATGTGGTGGCTGAATCAGCTTCGACGACT
    GAGTGGGCTGCTCAATTTGGCCTACCGATGATATTAAGTTGGATTATAAATACTAACGAA
    AAGAAAGCACAACTTGAGCTTTATAATGAAGTGGCTCAAGAATATGGGCACGATATTCAT
    AATATCGACCATTGCTTATCATATATAACATCTGTAGATCATGACTCAATTAAAGCGAAA
    GAGATTTGCCGGAAATTTCTGGGGCATTGGTATGATTCTTATGTGAATGCTACGACTATT
    TTTGATGATTCAGACCAAACAAGAGGTTATGATTTCAATAAAGGGCAGTGGCGTGACTTT
    GTATTAAAAGGACATAAAGATACTAATCGCCGTATTGATTACAGTTACGAAATCAATCCC
    GTGGGAACGCCGCAGGAATGTATTGACATAATTCAAAAAGACATTGATGCTACAGGAATA
    TCAAATATTTGTTGTGGATTTGAAGCTAATGGAACAGTAGACGAAATTATTGCTTCCATG
    AAGCTCTTCCAGTCTGATGTCATGCCATTTCTTAAAGAAAAACAACGTTCGCTATTATAT
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1083

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: CXP32_RS09750 [old locus tag: CXP32_09750 ]
  • symbol: CXP32_RS09750
  • description: alkanal monooxygenase
  • length: 360
  • theoretical pI: 6.2875
  • theoretical MW: 41000.3
  • GRAVY: -0.313611

Function[edit | edit source]

  • reaction:
    EC 1.14.14.3?  ExPASy
    Bacterial luciferase A long-chain aldehyde + FMNH2 + O2 = a long-chain fatty acid + FMN + H2O + light
  • TIGRFAM:
    natural product biosynthesis luciferase-like monooxygenase domain (TIGR04020; EC 1.-.-.-; HMM-score: 97.8)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv2161c family (TIGR03619; EC 1.-.-.-; HMM-score: 81.8)
    and 21 more
    probable oxidoreductase, LLM family (TIGR03858; EC 1.-.-.-; HMM-score: 73.8)
    Unknown function Enzymes of unknown specificity luciferase-type oxidoreductase, BA3436 family (TIGR03571; EC 1.-.-.-; HMM-score: 71.1)
    Unknown function Enzymes of unknown specificity putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family (TIGR04027; EC 1.-.-.-; HMM-score: 68.1)
    Unknown function Enzymes of unknown specificity luciferase family oxidoreductase, group 1 (TIGR03558; EC 1.-.-.-; HMM-score: 64.4)
    Unknown function Enzymes of unknown specificity putative luciferase-like monooxygenase, FMN-dependent, CE1758 family (TIGR04036; EC 1.-.-.-; HMM-score: 58.3)
    Metabolism Energy metabolism Methanogenesis 5,10-methylenetetrahydromethanopterin reductase (TIGR03555; EC 1.5.98.2; HMM-score: 46.2)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv1855c family (TIGR03560; HMM-score: 42.4)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2516 family (TIGR03621; HMM-score: 37.8)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, CPS_4043 family (TIGR03842; HMM-score: 35.2)
    Metabolism Central intermediary metabolism Sulfur metabolism dimethyl sulfone monooxygenase SfnG (TIGR04021; EC 1.14.-.-; HMM-score: 33.7)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, MSMEG_4879 family (TIGR03564; EC 1.-.-.-; HMM-score: 32.5)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_3544 family (TIGR03854; HMM-score: 26.2)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2249 family (TIGR03857; HMM-score: 24.9)
    Unknown function Enzymes of unknown specificity coenzyme F420-dependent oxidoreductase, NP1902A family (TIGR04024; EC 1.14.-.-; HMM-score: 23.3)
    Metabolism Central intermediary metabolism Sulfur metabolism alkanesulfonate monooxygenase, FMNH(2)-dependent (TIGR03565; EC 1.14.14.5; HMM-score: 21.8)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2906 family (TIGR03856; HMM-score: 17.9)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv3520c family (TIGR03559; HMM-score: 16)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_4141 family (TIGR03620; HMM-score: 15.2)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2256 family (TIGR03617; EC 1.-.-.-; HMM-score: 14.1)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, G6PDH family (TIGR03557; EC 1.-.-.-; HMM-score: 12.5)
    Unknown function Enzymes of unknown specificity FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family (TIGR03860; EC 1.-.-.-; HMM-score: 10.5)
  • TheSEED:
  • PFAM:
    no clan defined Bac_luciferase; Luciferase-like monooxygenase (PF00296; HMM-score: 164.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.923
    • Cytoplasmic Membrane Score: 0.0397
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0372
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005242
    • TAT(Tat/SPI): 0.000165
    • LIPO(Sec/SPII): 0.000413
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_033875256 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MKFGNFLLTYQPPQFSQTEVMKRLVKLGRISEECGFDTVWLLEHHFTEFGLLGNPYVAAAYLLGATKKLNVGTAAIVLPTAHPVRQLEDVNLLDQMSKGRFRFGICRGLYNKDFRVFGTDMNNSRALAECWYGLIKNGMTEGYMEADNEHIKFHKVKVNPAAYSRGGAPVYVVAESASTTEWAAQFGLPMILSWIINTNEKKAQLELYNEVAQEYGHDIHNIDHCLSYITSVDHDSIKAKEICRKFLGHWYDSYVNATTIFDDSDQTRGYDFNKGQWRDFVLKGHKDTNRRIDYSYEINPVGTPQECIDIIQKDIDATGISNICCGFEANGTVDEIIASMKLFQSDVMPFLKEKQRSLLY

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]