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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: DQM66_RS05110 [old locus tag: NCTC7466_00978 ]
  • pan locus tag?: PNEUPAN002237000
  • symbol: radC
  • pan gene symbol?: radC
  • synonym:
  • product: DNA repair protein RadC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: DQM66_RS05110 [old locus tag: NCTC7466_00978 ]
  • symbol: radC
  • product: DNA repair protein RadC
  • replicon: chromosome
  • strand: -
  • coordinates: 974932..975612
  • length: 681
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LS483374 (974932..975612) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0975 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGTACAGTATTTCATTCCAAGAAGATTCACTATTACCAAGAGAAAGGCTGGCCAAGGAA
    GGAGTTGAAGCGCTTAGTAACCAAGAGTTGCTAGCTATTTTACTCAGGACAGGAACACGT
    CAAGCTAGCGTTTTTGAAATTGCCCAAAAAGTCTTGAACAATCTTTCAAGCCTAACGGAT
    TTGAAAAAAATGACCCTGCAGGAATTGCAGAGTTTGTCTGGTATTGGGCGTGTTAAGGCC
    ATAGAATTACAAGCTATGATTGAACTGGGGCATCGTATTCACAAACACGAGACTCTTGAA
    ATGGAAAGTATTCTCAGCAGTCAAAAGTTGGCCAAGAAGATGCAGCAGGAATTAGGGGAT
    AAAAAACAAGAGCACCTGGTGGCACTCTATCTCAATACTCAAAATCAAATCATCCATCAG
    CAGACCATTTTTATCGGGTCTGTAACTCGTAGTATCGCTGAACCGCGAGAGATTCTTCAC
    TATGCAATCAAGCATATGGCGACTTCTCTTGTCTTGGTCCACAATCATCCTTCAGGAGCG
    GTAGCGCCTAGCCAAAATGATGATCATGTCACTAAACTTGTTAAAGAAGCCTGCGAACTG
    ATGGGGATTGTTCTCTTGGACCATTTGATTGTCTCTCATTCTAATTACTTTAGTTATCGT
    GAAAAGACAGATTTAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    681

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: DQM66_RS05110 [old locus tag: NCTC7466_00978 ]
  • symbol: RadC
  • description: DNA repair protein RadC
  • length: 226
  • theoretical pI: 7.18039
  • theoretical MW: 25521.3
  • GRAVY: -0.166372

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein RadC (TIGR00608; HMM-score: 236.9)
    and 1 more
    Cellular processes Cellular processes DNA transformation comEA protein (TIGR01259; HMM-score: 14.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    JAB (CL0366) RadC; RadC-like JAB domain (PF04002; HMM-score: 134.9)
    and 5 more
    no clan defined UPF0758_N; UPF0758 N-terminal (PF20582; HMM-score: 81.2)
    HHH (CL0198) HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 17.6)
    JAB (CL0366) Prok-JAB; Prokaryotic homologs of the JAB domain (PF14464; HMM-score: 16.3)
    HHH (CL0198) HHH_2; Helix-hairpin-helix motif (PF12826; HMM-score: 16.1)
    HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 14.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001794
    • TAT(Tat/SPI): 0.000983
    • LIPO(Sec/SPII): 0.000387
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000286923 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASVFEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEMESILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILHYAIKHMATSLVLVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFSYREKTDLI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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