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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_00770 [new locus tag: EF3030_RS00770 ]
  • pan locus tag?: PNEUPAN000832000
  • symbol: EF3030_00770
  • pan gene symbol?: —
  • synonym:
  • product: lantibiotic biosynthesis protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_00770 [new locus tag: EF3030_RS00770 ]
  • symbol: EF3030_00770
  • product: lantibiotic biosynthesis protein
  • replicon: chromosome
  • strand: +
  • coordinates: 140513..143392
  • length: 2880
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP035897 (140513..143392) NCBI
  • BioCyc: see EF3030_RS00770
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    GTGAACGTCTACAGTGTGATTTTAGAAAAACTTAATGAAAATAATCTTGAAATATTTTTT
    GATAGCAAAATATTTCAAGAGATGTTGATGGTGGCGAATCCACGATTTTTTAATGAATTA
    ACTAAGGAAAAAATATATCAAAATTCTACGTTTAGAAATTATGCAAAGAGGTCGCTTACA
    AGAGCAACTCCATTTGGATTGTTTAGTTCAGTTGGTGTTGGTTCTTTTTCAAAAGTTTCA
    TACCCTCAACAGATTAGAGAGAATTATAGTAAAAAAGTGTCTGTTAGTGGAGAGTGGATT
    AGTTCGCTTTGTATGATGTTAGAAAATGAAGATTCAGTTTTATTGCAATTACATTTACAG
    TGGAATCAAAAAGTACTGGAGCTATCAGATAAGTATCAATTGAATAATATCAACTATTGG
    GGTGTTTCCGAGCAGAGTAGAGATATACTTATCAAGAAAACTGCCCTTTTAGAATTTATT
    AAAAAATTGACATATAAATCGGAAGTAAGTGTATTAGACTTGGTACAAGAAATTCAAACT
    AAGTCTCCTAATTTGGAGACACAGAAAATTATTGATTATTTACGTAATTTAATTATCAGT
    GAATTTTTATTTACAAACTTACGAAAGGTTGTAATAAATCACAATTGTTTAGATAATTTA
    ATTTATATTTTAAGTTCTATTAATGAGCAAACAAAATTAACTACTGATTTGTTACAACTT
    AAATCATGCATCGAGAAGTATTCAAAATCAGAGTTAGGAGAAGGTATTCTTCAATATGCT
    GAAATTTGTGAAAAAATGTCTCATATTTTTAATGAAGAAAAACAGCGCTATCTGAAGGTT
    GACTTAGTGAATAGTTATGATTCGCTATTACCCAAAGATTTAAAAAAGACATTGGAGGAC
    TTCGTTAACTTTATTTCGAGAATTAATCTGGGTAAAGATTATCGAAATAAGGAATTAATC
    TCGTACACAGAAAAATTTGTCGAAAAATACGGAGAGTATGTTGAAGTTCCTATTAAGCAA
    CTACTGGATAGTAAGTTAGGGTTGGGGATACCAAAACAAAATTTGGAACCTTATAGTATA
    TTATCAAGTGTTGCAGAACAAACTTTTTTGTCTTATCTAAGTAAAGAAATCTTTAAAGCA
    GTGAAAAATAATAAAAAGGAAATTGATATATCAAATATTCCGCCTGAATTATTGTATCCA
    AATTTGGATAGATTTGCTGTGAATCAGTTCGAGTTGTATTGTGAAATGAAGAATTTTGGA
    GAACAACCTGTTATATCAATTGTGCCAAATACTGGGAGTGATATGATAGGAAAGTCTATT
    GGTAGATTTGCTTCATATTTTCTAAATTCTAATATAGAATTAGATTCGAGGGTTGATAAT
    GTAGAATTAATAGAATTTCCAAGTGATAATAAAAATTTAAATGTTATGTCTTCTCACCAT
    GGACATTCTAAAAAGTTATTACTATCTTATGAAGATGACTTTGATATTGACTCGTTAGAA
    TTAGATTTCTTAGTAGTGGGTGTTGAGAGAGTGAATGAGCATTACAAACTATATTTTAGA
    GACTTACGAACAGACTTGATTGTTAATTTTGTAACAACCTCAATGCTGAATCATAAATCT
    ATCGGAGTTTTTAGCCATTTAGCGAGATTTTTGTTAACAGTTTCGTTAGAGTGGCAAGAT
    AATCCATTTTCTCTATTTAGGGTAATTGAGAATCTTGATTTCCTTCCTTATATTCCTAGA
    ATTAAATATAAGAATATTATTTTAAGTGAAGAGAAGTGGATTTTATCAGATGTCGATAAA
    AAAGATATGTCTACTATTAGTCAGTGGAAAAAATTTTTTGATGTACCTAGCCTTCTATAC
    TTTCATAAAGATGATGAGCGTTTACTGATTGACCTAAAGAATAGTTTAGATGTTCAATGG
    ATTTTAAAACAAAATGTTGATAAATTACATTTTACGCGTTTTGATAAGATTGATGGTAAA
    AATTGCGAGTTTATCTTTGGATTTGAAAATCCTCGAAATAGTGTATACCCTCATTCAGTA
    AGTGAAAAAACTGTCAGAAGAATTGAAAATGACTTTTATAAAGATTATGTAAAAACGTTT
    TCGAGCGATTGGATATATTTCAAATTATATGGAATTAACTCCTCAACGATGCCTGAACTA
    AGAGAAAATCTTCTTATATTCACTGATGAGCTTTTAGCTGAGAAATTAGTTAGTGATTTT
    CATTTTGTAAATTATAATGATGGCGGGGATGGTTCTATTAGATTAAGGTTTAAAATTATG
    AACGAAGATGATTTTGAAAAGCTAAGATATCGAATTATTCATTGGATAGATTTCCTATTA
    AATCATTATTTTTGTAAAGATGTAAGTTTTAATTTATATGAGAGGGAGGTTGAGAGATAT
    GGAGGTATTGGCTTTTTAACAGTATGTGAGAGGATATTTTCTATTGATAGTTATCTTGTT
    TTAAAGTTGTTTTCAAAGAAAGTATTAAAAGTTGATGATTATTTATCTGTTCTACATTCA
    ATTTTTATATATATCCGACTATTGGGAATATCTCCAAAACAATTACTTAAATTGATGAAG
    GATACTTTTACTCAAAATATTTATCGTAAAAGTTTTAAAAAGGTGTTTCCCAATAACGCA
    AAAGTAATAAAGGAATTCAAACAATATTTTGAAGATCAAAGTAAATTTGATATTTTCAAT
    GAAGTTTTTAAAAGCTTCTCACCTATCGAGAAACATTTTGAATATAAAAATGATATGATT
    CATAGTTTGCTTCATATGCACATGAATAGAATAGGAATATTTTCCTTAAATGAAAAGGAA
    TATCTTTATTTTGTGAGGTATATTTTAGAGGTATTAAATAATTATGAGAAATATAATTAA
    60
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    420
    480
    540
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    660
    720
    780
    840
    900
    960
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    1140
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    2040
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    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_00770 [new locus tag: EF3030_RS00770 ]
  • symbol: EF3030_00770
  • description: lantibiotic biosynthesis protein
  • length: 959
  • theoretical pI: 6.68755
  • theoretical MW: 113492
  • GRAVY: -0.285506

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Toxin production and resistance thiopeptide-type bacteriocin biosynthesis domain (TIGR03891; HMM-score: 202)
  • TheSEED:
  • PFAM:
    no clan defined Lant_dehydr_N; Lantibiotic dehydratase, N terminus (PF04738; HMM-score: 262.9)
    and 2 more
    Lant_dehydr_C; Lantibiotic biosynthesis dehydratase C-term (PF14028; HMM-score: 68.3)
    ACT (CL0070) Thr_dehydrat_C; C-terminal regulatory domain of Threonine dehydratase (PF00585; HMM-score: 17)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.1458
    • Cytoplasmic Membrane Score: 0.7962
    • Cell wall & surface Score: 0.001
    • Extracellular Score: 0.057
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002396
    • TAT(Tat/SPI): 0.000203
    • LIPO(Sec/SPII): 0.000534
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QBF68187 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNVYSVILEKLNENNLEIFFDSKIFQEMLMVANPRFFNELTKEKIYQNSTFRNYAKRSLTRATPFGLFSSVGVGSFSKVSYPQQIRENYSKKVSVSGEWISSLCMMLENEDSVLLQLHLQWNQKVLELSDKYQLNNINYWGVSEQSRDILIKKTALLEFIKKLTYKSEVSVLDLVQEIQTKSPNLETQKIIDYLRNLIISEFLFTNLRKVVINHNCLDNLIYILSSINEQTKLTTDLLQLKSCIEKYSKSELGEGILQYAEICEKMSHIFNEEKQRYLKVDLVNSYDSLLPKDLKKTLEDFVNFISRINLGKDYRNKELISYTEKFVEKYGEYVEVPIKQLLDSKLGLGIPKQNLEPYSILSSVAEQTFLSYLSKEIFKAVKNNKKEIDISNIPPELLYPNLDRFAVNQFELYCEMKNFGEQPVISIVPNTGSDMIGKSIGRFASYFLNSNIELDSRVDNVELIEFPSDNKNLNVMSSHHGHSKKLLLSYEDDFDIDSLELDFLVVGVERVNEHYKLYFRDLRTDLIVNFVTTSMLNHKSIGVFSHLARFLLTVSLEWQDNPFSLFRVIENLDFLPYIPRIKYKNIILSEEKWILSDVDKKDMSTISQWKKFFDVPSLLYFHKDDERLLIDLKNSLDVQWILKQNVDKLHFTRFDKIDGKNCEFIFGFENPRNSVYPHSVSEKTVRRIENDFYKDYVKTFSSDWIYFKLYGINSSTMPELRENLLIFTDELLAEKLVSDFHFVNYNDGGDGSIRLRFKIMNEDDFEKLRYRIIHWIDFLLNHYFCKDVSFNLYEREVERYGGIGFLTVCERIFSIDSYLVLKLFSKKVLKVDDYLSVLHSIFIYIRLLGISPKQLLKLMKDTFTQNIYRKSFKKVFPNNAKVIKEFKQYFEDQSKFDIFNEVFKSFSPIEKHFEYKNDMIHSLLHMHMNRIGIFSLNEKEYLYFVRYILEVLNNYEKYN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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