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TIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_11060
  • pan locus tag?:
  • symbol: EF3030_11060
  • pan gene symbol?: —
  • synonym:
  • product: YhgE/Pip domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_11060
  • symbol: EF3030_11060
  • product: YhgE/Pip domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2094713..2095480
  • length: 768
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP035897 (2094713..2095480) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGATCGGGATTTCTCTTATTCCAGATCTGTACAATATCATATTTTTGTCATCAATGTGG
    GATCCATATGGGCAATTGTCTGACTTACCTGTGGCAGTTGTAAATAATGATAAAGAGGCT
    TCCTATAATGGTAATACTATGGCAATAGGAAAAGACATGGTGTCCAATTTAAAAGAAAAT
    AAAACCTTGGATTTTCATTTTGTAGATGAAGAGGAAGGAAAGAAGGGATTGGAAGATGGC
    GATTACTATATGGTAGTGACTTTACCAAGTGATTTATCTGAAAAAACAACTACATTATCC
    AATATTCAATCGACAGCAGCTTATCAATCATTGACAAGTGAGCAACAAACTGAGATAAGT
    GATTCTGTATCTCAAAATTCAACTGATAGTATTCAATCGGCTCAGTCAATTGTAGCTTTA
    GTACAAGATTTACAGGGAAGTTTAGAAAACTTACAAAATCAATCTTCTAATCTTTCGACT
    TTAAAAAATCAATCTAATCAAGTATCACCTATTACTTCTACTTCTTTGATAGGATTGTCA
    AGTGGATTAACAGAGATACAAGGAGATGTTACTAGCAAATTAGTTCCTGCCAGTCAGTCG
    ATTGCATCAGGTGTAAACGCATATACTACAGGTGTTGATAAAGTTTCTCAGGGCGCAAGT
    CAACTAAGTGAAAAAAATGCCACCTTGACAGGTAGTTTGAATAAACTAGTTTCAGGCTCA
    AACACCTTGACACAAAAATCTTCTAGATTGACAGCAGGAGTTGGTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    768

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_11060
  • symbol: EF3030_11060
  • description: YhgE/Pip domain-containing protein
  • length: 255
  • theoretical pI: 4.10252
  • theoretical MW: 27032.7
  • GRAVY: -0.278824

⊟Function[edit | edit source]

  • TIGRFAM:
    YhgE/Pip N-terminal domain (TIGR03061; HMM-score: 146.6)
    and 3 more
    type VII secretion protein EsaA (TIGR03929; HMM-score: 54.6)
    X-X-X-Leu-X-X-Gly heptad repeats (TIGR03057; HMM-score: 21.2)
    SH3 domain protein (TIGR04211; HMM-score: 19.4)
  • TheSEED:
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane_3; ABC-2 family transporter protein (PF12698; HMM-score: 43.1)
    and 6 more
    DUF3533; Protein of unknown function (DUF3533) (PF12051; HMM-score: 32)
    no clan defined Med21; Subunit 21 of Mediator complex (PF11221; HMM-score: 16.2)
    DUF3294; Protein of unknown function (DUF3294) (PF07957; HMM-score: 12.7)
    BORCS6; BLOC-1-related complex sub-unit 6 C-terminal helix (PF10157; HMM-score: 10.9)
    Vps51 (CL0295) Sec8_exocyst; Sec8 exocyst complex component specific domain (PF04048; HMM-score: 10.1)
    no clan defined DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 8.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.21
    • Cytoplasmic Membrane Score: 2.35
    • Cellwall Score: 0.65
    • Extracellular Score: 6.8
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.7606
    • Cell wall & surface Score: 0.0355
    • Extracellular Score: 0.2037
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.049482
    • TAT(Tat/SPI): 0.001368
    • LIPO(Sec/SPII): 0.013975
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QBF69922 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNGNTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNIQSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLSTLKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQGASQLSEKNATLTGSLNKLVSGSNTLTQKSSRLTAGVG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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