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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS05575 [old locus tag: SPAT_1051 ]
  • pan locus tag?: PNEUPAN002268000
  • symbol: glgB
  • pan gene symbol?: glgB
  • synonym:
  • product: 1,4-alpha-glucan branching protein GlgB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS05575 [old locus tag: SPAT_1051 ]
  • symbol: glgB
  • product: 1,4-alpha-glucan branching protein GlgB
  • replicon: chromosome
  • strand: +
  • coordinates: 1042966..1044894
  • length: 1929
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1042966..1044894) NCBI
  • BioCyc: EL263_RS05575 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1005 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGGATAATAGAGAAGCATTAAAAACCTTTATGACGGGTGAAAATTTTTATCTCCAACAT
    TATCTAGGAGCACATAGGGAAGAACTAAATGGAGAGCATGGCTATACCTTCCGTGTTTGG
    GCACCTAATGCTCAGGCTGTTCACTTGGTTGGTGATTTTACCAACTGGATTGAAAATCAG
    ATTCCAATGGTAAGAAATGATTTTGGGGTCTGGGAAGTCTTTACCAATATGGCTCAAGAA
    GGGCATATTTACAAATATCATGTCACACGTCAAAATGGTCATCAACTGATGAAGATTGAC
    CCTTTTGCTGTCAGGTATGAGGCTCGTCCAGGAACAGGGGCAATCTTAACAGAGCTTCCT
    GAGAAGAAATGGAAGGATGGACTTTGGCTGGCACGAAGAAAACGTTGGGGCTTTGAAGAG
    CGTCCTGTCAATATTTATGAAGTTCACGCTGGATCATGGAAAAGAAATTCTGATGGCAGT
    CCTTATAGTTTTGCCCAGCTCAAGGATGAACTCATTCCTTATCTCGTTGAAATGAACTAT
    ACTCATATTGAGTTTATGCCCTTGATGTCCCATCCTTTGGGCTTGAGTTGGGGGTATCAG
    CTTATGGGTTACTTCGCTTTAGAGCATGCTTATGGCCGACCAGAGGAGTTTCAAGATTTT
    GTCGAGGAGTGTCATACCCATAATATTGGGGTTATTGTGGACTGGGTACCAGGTCACTTT
    ACCATCAACGATGATGCCTTAGCCTATTATGATGGGACACCGACTTTTGAATACCAAGAC
    CATAATAAGGCTCATAACCATGGTTGGGGTGCCCTTAATTTTGACCTTGGAAAAAATGAA
    GTTCAGTCCTTCTTAATTTCTTGCATTAAGCATTGGATTGATGTCTATCATTTGGATGGT
    ATTCGTGTGGATGCTGTTAGCAACATGCTCTATTTGGACTATGATGATGCTCCATGGACA
    CCTAATAAAGATGGCGGAAATCTCAACTATGAAGGTTATTATTTTCTTCAACGCTTGAAT
    GAAGTTATTAAGTTAGAATATCCAGATGTGATGATGATTGCAGAAGAAAGTTCGTCTGCG
    ACCAAGATTACGGGAATGAAAGAGATTGGTGGTCTAGGATTTGACTACAAATGGAACATG
    GGCTGGATGAATGATATCCTCCGTTTCTACGAAGAAGATCCGATTTATCGTAAATATGAC
    TTTAACCTGGTGACTTTCAGCTTTATGTATGTTTTCAAGGAGAATTATCTCTTGCCATTC
    TCGCACGATGAAGTGGTTCATGGCAAGAAGAGTATGATGCATAAGATGTGGGGAGATCGT
    TACAATCAATTCGCAGGCTTGCGCAATCTCTATACGTACCAAATTTGTCACCCTGGTAAG
    AAATTGCTCTTCATGGGTAGCGAATACGGTCAATTCCTAGAATGGAAATCTGAAGAACAG
    TTGGAATGGTCTAACCTAGAAGACCCAATGAATGCTAAGATGAAGTATTTCACTTCTCAG
    CTAAACCAGTTTTACAAAGATCATCGCTGTCTGTGGGAAATCGATACCAGCTATGATGGT
    ATTGAAATCATTGATGCGGATAATCGAGACCAGAGTGTTCTTTCCTTTATTCGTAAGGGT
    AAAAAGGGAGAAATGTTAGTCTGTATCTTTAACATGGTACCTGTTGAGCGGAAAGATTTT
    ACAATCGGACTACCCGTTGCAGGAATTTACGAAGAAGTATGGAATACTGAGTTGGAAGAG
    TGGGGAGGCGTTTGGAAAGAACATAATCAAACTGTTCAAACGCAAGAAGGCCTATGGAAA
    GATTATGAGCAGACCTTAACCTTTACTCTACCGGCTATGGGAGCAAGTGTATGGAAAATC
    AAACGTCGCTTGAAATCTACTAAAACCGTCACAAATAAAAACCAAAAAGGAGTAGAAAAT
    GAAAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1929

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS05575 [old locus tag: SPAT_1051 ]
  • symbol: GlgB
  • description: 1,4-alpha-glucan branching protein GlgB
  • length: 642
  • theoretical pI: 5.56263
  • theoretical MW: 75635
  • GRAVY: -0.573209

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides 1,4-alpha-glucan branching enzyme (TIGR01515; EC 2.4.1.18; HMM-score: 672.1)
    and 8 more
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides malto-oligosyltrehalose trehalohydrolase (TIGR02402; EC 3.2.1.141; HMM-score: 135.2)
    pullulanase, type I (TIGR02104; EC 3.2.1.41; HMM-score: 67)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides trehalose synthase (TIGR02456; EC 5.4.99.16; HMM-score: 54.3)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen debranching enzyme GlgX (TIGR02100; EC 3.2.1.-; HMM-score: 50)
    pullulanase, extracellular (TIGR02102; HMM-score: 38.7)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides malto-oligosyltrehalose synthase (TIGR02401; EC 5.4.99.15; HMM-score: 32.6)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides alpha-1,6-glucosidases, pullulanase-type (TIGR02103; EC 3.2.1.41; HMM-score: 27.1)
    alpha,alpha-phosphotrehalase (TIGR02403; EC 3.2.1.93; HMM-score: 27.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    GHD (CL0369) CBM_48; Carbohydrate-binding module 48 (Isoamylase N-terminal domain) (PF02922; HMM-score: 82.9)
    and 4 more
    Alpha-amylase_C; Alpha amylase, C-terminal all-beta domain (PF02806; HMM-score: 63.4)
    Glyco_hydro_tim (CL0058) Alpha-amylase; Alpha amylase, catalytic domain (PF00128; HMM-score: 48.4)
    GHD (CL0369) AMPK1_CBM; Glycogen recognition site of AMP-activated protein kinase (PF16561; HMM-score: 22.7)
    no clan defined DUF4913; Domain of unknown function (DUF4913) (PF16259; HMM-score: 14.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004753
    • TAT(Tat/SPI): 0.000703
    • LIPO(Sec/SPII): 0.00062
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000370242 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNAQAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPFAVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGSPYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQDFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDLGKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYYFLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEEDPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNLYTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFTSQLNQFYKDHRCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPVAGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRLKSTKTVTNKNQKGVENEK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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