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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS06265 [old locus tag: SPAT_1187 ]
  • pan locus tag?: PNEUPAN002538000
  • symbol: rsmG
  • pan gene symbol?: rsmG
  • synonym:
  • product: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS06265 [old locus tag: SPAT_1187 ]
  • symbol: rsmG
  • product: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
  • replicon: chromosome
  • strand: +
  • coordinates: 1193543..1194256
  • length: 714
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1193543..1194256) NCBI
  • BioCyc: EL263_RS06265 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1140 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAAACCAGAAACATTTTACAACTTGCTTGCCGAGCAGAATCTTCCACTTTCGAACCAG
    CAAAAAGAACAATTTGAACGTTATTTTGAGCTCTTGGTCGAGTGGAATGAGAAGATTAAT
    TTGACGGCGATTACGGACAAGGAAGAAGTTTATCTCAAACATTTTTACGATTCGATTGCA
    CCCATTCTTCAAGGTTTGATTCCCAATGAAACTATCAAACTTCTTGATATCGGGGCTGGG
    GCAGGATTTCCTAGTCTACCAATGAAAATTCTCTATCCGGAGTTAGATGTGACCATTATT
    GATTCACTCAATAAGCGCATCAACTTCCTACAACTCTTGGCTCAAGAACTGGATTTGAAC
    GGAGTTCATTTCTACCACGGACGTGCCGAAGATTTTGCCCAAGACAAGAACTTCCGTGCT
    CAATATGATTTTGTAACAGCTCGTGCGGTTGCCCGTATGCAGGTCCTATCTGAATTGACT
    ATTCCCTACCTTAAGGTTGGTGGCAAACTATTGGCACTCAAGGCCAGCAATGCGCCTGAG
    GAATTATTAGAAGCTAAGAATGCCCTCAATCTCCTTTTTAGTAAGGTCGAAGACAATCTC
    AGCTACGCCCTACCGAATAGAGATCCGCGCTATATCACAGTGGTAGAAAAGAAAAAAGAA
    ACACCAAATAAATATCCACGTAAGACTGGTATGCCAAATAAACGCCCACTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    714

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS06265 [old locus tag: SPAT_1187 ]
  • symbol: RsmG
  • description: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG
  • length: 237
  • theoretical pI: 6.81921
  • theoretical MW: 27228.2
  • GRAVY: -0.351477

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.1.170?  ExPASy
    16S rRNA (guanine527-N7)-methyltransferase S-adenosyl-L-methionine + guanine527 in 16S rRNA = S-adenosyl-L-homocysteine + N7-methylguanine527 in 16S rRNA
  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG (TIGR00138; EC 2.1.1.170; HMM-score: 157.7)
    and 6 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 3-demethylubiquinone-9 3-O-methyltransferase (TIGR01983; EC 2.1.1.64; HMM-score: 29.5)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit (TIGR02469; EC 2.1.1.132; HMM-score: 25.8)
    Genetic information processing Protein fate Protein modification and repair protein-(glutamine-N5) methyltransferase, release factor-specific (TIGR03534; EC 2.1.1.-; HMM-score: 18)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin malonyl-acyl carrier protein O-methyltransferase BioC (TIGR02072; EC 2.1.1.-; HMM-score: 17)
    methyltransferase, Rta_06860 family (TIGR04290; EC 2.1.1.-; HMM-score: 15.7)
    Genetic information processing Protein fate Protein modification and repair methyltransferase, HemK family (TIGR00536; HMM-score: 12.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    NADP_Rossmann (CL0063) GidB; rRNA small subunit methyltransferase G (PF02527; HMM-score: 164.2)
    and 8 more
    Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 29.1)
    MTS; Methyltransferase small domain (PF05175; HMM-score: 23.7)
    Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 19.9)
    TehB; Tellurite resistance protein TehB (PF03848; HMM-score: 19.6)
    no clan defined DUF2999; Protein of unknown function (DUF2999) (PF11212; HMM-score: 17.6)
    NADP_Rossmann (CL0063) Methyltransf_12; Methyltransferase domain (PF08242; HMM-score: 16.4)
    Methyltransf_11; Methyltransferase domain (PF08241; HMM-score: 15.1)
    Methyltransf_32; Methyltransferase domain (PF13679; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9982
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0013
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002549
    • TAT(Tat/SPI): 0.000144
    • LIPO(Sec/SPII): 0.000296
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000801942 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAITDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDSLNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELTIPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKKKETPNKYPRKTGMPNKRPL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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