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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS06490
  • pan locus tag?: PNEUPAN002668000
  • symbol: EL263_RS06490
  • pan gene symbol?: —
  • synonym:
  • product: sodium:solute symporter

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS06490
  • symbol: EL263_RS06490
  • product: sodium:solute symporter
  • replicon: chromosome
  • strand: -
  • coordinates: 1232723..1234264
  • length: 1542
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1232723..1234264) NCBI
  • BioCyc: EL263_RS06490 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGGGCACAACAGGATTTACAATAATTGACTTAATTATCTTGATTGTTTATTTACTTGCG
    GTGTTGGTTGCAGGTATCTATTTCTCTAAAAAAGAGATGAAAGGAAAAGAGTTCTTTAAA
    GGAGATGGTTCGGTTCCTTGGTATGTTACTTCGGTATCCATTTTTGCCACAATGCTCAGT
    CCGATTTCCTTCTTGGGACTCGCTGGTAGCTCTTATGCAGGTAGCTGGATTTTATGGTTT
    GCTCAATTAGGGATGGTAGTAGCTATTCCACTGACAATTCGTTTTATCTTACCTATCTTT
    GCACGGATAGACATCGATACGGCATATGATTACTTGGATAAACGTTTTAATTCTAAAGCA
    CTTCGTATTATTTCAGCACTCTTGTTTATTATTTATCAATTGGGACGTATGTCTATCATT
    ATGTACCTCCCATCAGCTGGTTTATCAGTATTGACAGGAATTGACATCAATATTTTGATT
    ATTTTGATGGGTGTAGTTGCAATTGTTTATTCTTATACTGGTGGTCTAAAATCCGTATTA
    TGGACAGACTTTATTCAAGGTGTGATTCTGATTAGTGGTGTCGTTTTAGCTTTATTTGTA
    CTGATTGCTAATATTAAAGGTGGCTTTGGTGCAGTAGCAGAAACATTAGCAAACGGGAAA
    TTCCTTGCTGCAAATGAAAAACTTTTCGATCCTAACTTGCTTTCAAACTCCATCTTTTTA
    ATTGTGATGGGTTCAGGCTTTACAATCTTGTCTTCCTATGCTTCATCTCAAGATTTGGTT
    CAACGTTTTACTACAACACAAAATATTAAGAAACTTAATAAGATGTTGTTCACAAACGGT
    GTTTTGTCACTTGCAACTGCAACAGTCTTTTACTTGATTGGTACAGGCTTGTACGTATTC
    TATCAAGTACAAAATGCAGATAGTGCAGCTAGCAATATCCCTCAAGACCAAATCTTTATG
    TACTTTATTGCATACCAGTTACCAGTAGGTATCACAGGTTTGATCTTGGCAGCGATTTAT
    GCAGCATCTCAATCAACTATTTCAACAGGTTTGAACTCTGTTGCAACTTCATGGACATTG
    GATATTCAAGATGTCATTTCTAAAAATATGTCAGACAATCGTCGTACGAAAATTGCACAA
    TTCGTATCTCTAGCAGTAGGTTTATTCTCAATTGGTGTTTCCATTGTCATGGCTCACTCA
    GATATTAAATCTGCATACGAATGGTTCAATAGTTTCATGGGACTTGTACTTGGTCTACTT
    GGTGGTGTATTTATTCTTGGATTTGTTTCTAAAAAAGCAAATAAACAAGGTGCTTATGCA
    GCGCTGATTGTATCAACCATCGTCATGGTATTTATTAAATACTTCCTTCCTCCAACAGCT
    GTTAGCTACTGGGCATATTCATTGATTTCAATCTCTGTATCAGTAGTTTCAGGTTATATT
    GTATCTGTTCTTACTGGAAATAAAGTATCTGCACCTAAATATACAACGATTCATGATATT
    ACAGAAATTAAAGCGGATTCAAGTTGGGAAGTTCGTCACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1542

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS06490
  • symbol: EL263_RS06490
  • description: sodium:solute symporter
  • length: 513
  • theoretical pI: 9.59185
  • theoretical MW: 55768.3
  • GRAVY: 0.765692

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Cations and iron carrying compounds transporter, solute:sodium symporter (SSS) family (TIGR00813; HMM-score: 219.3)
    and 6 more
    Metabolism Transport and binding proteins Amino acids, peptides and amines sodium/proline symporter (TIGR02121; HMM-score: 94.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A sodium/pantothenate symporter (TIGR02119; HMM-score: 73.6)
    Metabolism Transport and binding proteins Other sodium/pantothenate symporter (TIGR02119; HMM-score: 73.6)
    probable sodium:solute symporter, VC_2705 subfamily (TIGR03648; HMM-score: 45.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids cation/acetate symporter ActP (TIGR02711; HMM-score: 29.4)
    grasp-with-spasm leader A domain (TIGR04194; HMM-score: 9.4)
  • TheSEED: data available for Hungary19A-6, TIGR4
  • PFAM:
    APC (CL0062) SSF; Sodium:solute symporter family (PF00474; HMM-score: 132)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.008059
    • TAT(Tat/SPI): 0.000223
    • LIPO(Sec/SPII): 0.013406
  • predicted transmembrane helices (TMHMM): 13

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000537366 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGSVPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFARIDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILIILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLANGKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKMLFTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGLILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIGVSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMVFIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSSWEVRH

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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