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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS08355 [old locus tag: SPAT_1592 ]
  • pan locus tag?: PNEUPAN003129000
  • symbol: EL263_RS08355
  • pan gene symbol?: scrA
  • synonym:
  • product: PTS beta-glucoside transporter subunit IIBCA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS08355 [old locus tag: SPAT_1592 ]
  • symbol: EL263_RS08355
  • product: PTS beta-glucoside transporter subunit IIBCA
  • replicon: chromosome
  • strand: -
  • coordinates: 1580161..1582032
  • length: 1872
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1580161..1582032) NCBI
  • BioCyc: EL263_RS08355 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1532 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    ATTGCAAAAAAAGTCATCGATGCCTTGGGCGGACGTGAAAATGTCAACAGTGTTGCCCAC
    TGTGCGACTCGTCTTCGTGTCATGGTCAAAGATGAAGGAAAAATCAATAAAGAAGTGATT
    GAGAACTTGGAAAAAGTTCAAGGTGCTTTCTTTAACTCAGGTCAATACCAAATCATCTTT
    GGTACTGGTACAGTTAACAAAATGTACGATGAAGTTGTTGCGCTTGGTTTGCCAACATCA
    TCTAAAGATGACATGAAAGCAGAAGCTGCTAAACAGGGGAACTGGTTCCAACGTGCTATC
    CGTACTTTCGGTGACGTTTTCGTTCCAATCATCCCAGTTATCGTAGCGACAGGTCTCTTC
    ATGGGTGTTCGTGGTCTTTTCAACGCTCTTGAAATGCCACTTCCAGGTGACTTTGCAACT
    TACACTCAAATCTTGACAGATACAGCCTTTATCATCTTGCCAGGTTTGGTTGTCTGGTCA
    ACCTTCCGTGTATTTGGTGGAAATCCTGCCGTTGGTATCGTTCTTGGTATGATGCTTGTT
    TCTGGTTCACTTCCAAATGCTTGGGCAGTTGCTCAAGGTGGTGAAGTAACAGCGATGAAC
    TTCTTTGGTTTCATTCCTGTTGTTGGTTTGCAAGGTTCCGTTCTTCCAGCATTCATCATC
    GGGGTTGTCGGAGCTAAATTTGAAAAAGCTGTCCGCAAGGTCGTTCCAGATGTCATTGAC
    CTTTTGGTAACACCATTCGTGACACTTTTGGTTATGTCTATCCTTGGACTCTTTGTCATC
    GGACCAGTCTTCCACGTCGTTGAAAACTACATCCTTATCGCTACAAAAGCGATCCTTAGC
    ATGCCATTTGGTCTTGGTGGTTTCTTGATTGGTGGGGTTCACCAATTGATCGTCGTGTCA
    GGTGTGCACCACATCTTCAACTTGCTTGAAGTTCAATTGCTTGCTGCTGATCATGCTAAC
    CCATTCAACGCGATCATCACAGCTGCTATGACAGCTCAAGGTGCTGCGACTGTTGCGGTC
    GGTGTTAAAACGAAAAATCCAAAACTGAAAACACTTGCTTTCCCAGCTGCTCTTTCTGCC
    TTCCTCGGTATTACAGAGCCTGCTATCTTCGGGGTTAACTTGCGTTTCCGTAAACCATTC
    TTCCTTTCATTGATTGCTGGTGCAATCGGTGGTGGATTGGCTTCTATCCTTGGACTTGCT
    GGTAATGGTAGTGGTATCACCATCATCCCTGGTACAATGCTTTATGTTGGTAACGGACAA
    CTTGTACAATACATTCTTATGGTAGCTGTATCATTTGCCCTTGGTTTTGCCCTTACTTAC
    ATGTTTGGTTATGAGGACGAAGAAGAAGTTGCTACTGAAGCGGCGACAGAACGTTTGGTC
    CAAGAAGAAACAACTGGCAACATTCCAGCAGCCCTTCAAAATGAAACACTTGTAACTCCT
    ATCGTTGGTGATATTGTCGCTCTTGCTGATGTCAATGATCCAGTTTTCTCAAGTGGAGCT
    ATGGGACAAGGTATCGCTGTGAAACCAAGTCAAGGTGTGGTATATGCACCAGCTGATGCT
    GAAGTTTCAATCGCCTTTCCAACAGGACACGCTTTTGGTTTGAAAACAACTGATGGTACT
    GAAGTTTTGATCCACGTTGGTATTGACACTGTGTCTATGAATGGTGACGGTTTTGAAGCA
    AAAGTTACTCAAGGTGATAAGGTTAAAGCTGGCGATATTCTTGGAACATTTGACTCAAAT
    AAAATCGCTGCAGCTGGTCTTGATGATACAACAATGGTTATCGTTACAAATACAGCTGAC
    TACGCTTCAGTAGCTCCAGTCGCAACAGGTTCAGTTGCGAAGGGGGATGCTGTGATCGAG
    GTGAAAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1872

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS08355 [old locus tag: SPAT_1592 ]
  • symbol: EL263_RS08355
  • description: PTS beta-glucoside transporter subunit IIBCA
  • length: 623
  • theoretical pI: 4.88209
  • theoretical MW: 65138.4
  • GRAVY: 0.581862

⊟Function[edit | edit source]

  • TIGRFAM:
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 556.8)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 496.1)
    and 12 more
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 332.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 159.2)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 159.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 146.2)
    Signal transduction Signal transduction PTS PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 146.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 72.7)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 72.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 35.7)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 35.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 32.2)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 26.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 25.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Hybrid (CL0105) PTS_EIIA_1; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PF00358; HMM-score: 162.8)
    and 6 more
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 118.6)
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 57.4)
    Hybrid (CL0105) Biotin_lipoyl_2; Biotin-lipoyl like (PF13533; HMM-score: 21.1)
    Peptidase_M23; Peptidase family M23 (PF01551; HMM-score: 19.6)
    no clan defined DUF4396; Domain of unknown function (DUF4396) (PF14342; HMM-score: 14)
    ATP-synt_ab_Xtn; ATPsynthase alpha/beta subunit N-term extension (PF16886; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01221
    • TAT(Tat/SPI): 0.00051
    • LIPO(Sec/SPII): 0.001443
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_172953611 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAKKVIDALGGRENVNSVAHCATRLRVMVKDEGKINKEVIENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVALGLPTSSKDDMKAEAAKQGNWFQRAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPGLVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGSVLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYILIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAAMTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAGAIGGGLASILGLAGNGSGITIIPGTMLYVGNGQLVQYILMVAVSFALGFALTYMFGYEDEEEVATEAATERLVQEETTGNIPAALQNETLVTPIVGDIVALADVNDPVFSSGAMGQGIAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTTDGTEVLIHVGIDTVSMNGDGFEAKVTQGDKVKAGDILGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIEVKI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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