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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS11525 [old locus tag: SPAT_1857 ]
  • pan locus tag?: PNEUPAN003545000
  • symbol: EL263_RS11525
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS11525 [old locus tag: SPAT_1857 ]
  • symbol: EL263_RS11525
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1825091..1825507
  • length: 417
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1825091..1825507) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAATACCATAGAGCGGACTAGGCGGCTGGTTAAAGGCTGCGCAACACACTGTTTTGAG
    GTTGTAGATAGAACTGACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTAGATGAAACT
    AACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTAGATGAAACTAACGAAGTCAGCTCA
    AAGCACTGCTTTGAGGTTGCAGATGAAACTGACGAAGTCAGCTCAAAGCACTGCTTTGAG
    GTTGCAGATGAAACTGACGAAGTCAGCTCAAAGCACTGCTTTGAGGTTGCAGATGAAACT
    GACGAAGTCAGCTCAAAACATGTTTTTGAGGTTGTGGATGAAACTGACGAAGTCAGTAAC
    CATACATACGGTAAGGCGACGCTGACGTGGTTTGCAGAGATTTTCGAAGAGTATTAG
    60
    120
    180
    240
    300
    360
    417

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: EL263_RS11525 [old locus tag: SPAT_1857 ]
  • symbol: EL263_RS11525
  • description: hypothetical protein
  • length: 138
  • theoretical pI: 4.14095
  • theoretical MW: 15806
  • GRAVY: -0.573913

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General ROK family protein (putative glucokinase) (TIGR00744; HMM-score: 17.7)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    PDZ-like (CL0466) PDZ_4; PDZ domain (PF17816; HMM-score: 14.6)
    NusB (CL0633) DUF1948; Domain of unknown function (DUF1948) (PF09185; HMM-score: 13.7)
    HTH (CL0123) YdaS_antitoxin; Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT (PF15943; HMM-score: 12.3)
    no clan defined DUF1810; Protein of unknown function (DUF1810) (PF08837; HMM-score: 12)
    and 4 more
    Phage_TACs (CL0567) Phage_TAC_8; Phage tail assembly chaperone protein Gp14 ()A118 (PF10666; HMM-score: 10)
    no clan defined CMV_1a_C; Cucumber mosaic virus 1a protein C terminal (PF12503; HMM-score: 10)
    PH (CL0266) PH; PH domain (PF00169; HMM-score: 9.8)
    no clan defined DUF3638; Protein of unknown function (DUF3638) (PF12340; HMM-score: 7.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007886
    • TAT(Tat/SPI): 0.001538
    • LIPO(Sec/SPII): 0.001396
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_061849636 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNTIERTRRLVKGCATHCFEVVDRTDEVSSKHVFEVVDETNEVSSKHVFEVVDETNEVSSKHCFEVADETDEVSSKHCFEVADETDEVSSKHCFEVADETDEVSSKHVFEVVDETDEVSNHTYGKATLTWFAEIFEEY

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]