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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS04675 [old locus tag: SPOH_0861 ]
  • pan locus tag?: PNEUPAN002001000
  • symbol: EL271_RS04675
  • pan gene symbol?: —
  • synonym:
  • product: EGFR-like transmembrane domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS04675 [old locus tag: SPOH_0861 ]
  • symbol: EL271_RS04675
  • product: EGFR-like transmembrane domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 864192..864608
  • length: 417
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (864192..864608) NCBI
  • BioCyc: EL271_RS04675 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0884 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    GTGAAGGCTGCCTTGGACTCTCTCAAAGATGTGAAAGCAAATGCTAGCGACAGCAAGCCT
    GCACAGGACAAGAAGGATGCAAAACAAGGAACGGAAGATAGTAAGGATTCAGATAAGATG
    ACTGAAACAAACTCAGTTCCGGCAGGAGTGATTGTGGTCAGTCTACTTGCCCTCCTAGGC
    GTGATTGCCTTCTGGCTGATTCGCCGTAAGAAAGAGTCAGAAATCCAGCAATTAAGCACG
    GAATTGATCAAGGTTCTAGGACAGCTAGATGCAGAAAAAGCGGATAAAAAAGTCCTTGCC
    AAAGCCCAAAACCTTCTCCAAGAAACCCTTGATTTCGTGAAAGAAGAAAATGGCTCAGCA
    GAGACAGAAACTAAACTAGTAGAGGAGCTTAAAGCAATCCTTGACAAACTCAAGTAA
    60
    120
    180
    240
    300
    360
    417

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS04675 [old locus tag: SPOH_0861 ]
  • symbol: EL271_RS04675
  • description: EGFR-like transmembrane domain-containing protein
  • length: 138
  • theoretical pI: 5.08179
  • theoretical MW: 15122.3
  • GRAVY: -0.422464

⊟Function[edit | edit source]

  • TIGRFAM:
    SH3 domain protein (TIGR04211; HMM-score: 15.3)
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 13.5)
    putative ABC transporter PGF-CTERM-modified substrate-binding protein (TIGR04281; HMM-score: 12.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Orf78; Orf78 (ac78) (PF06024; HMM-score: 22.1)
    CD99L2; CD99 antigen like protein 2 (PF12301; HMM-score: 17.8)
    and 3 more
    DUF4381; Domain of unknown function (DUF4381) (PF14316; HMM-score: 16)
    MFS (CL0015) CLN3; CLN3 protein (PF02487; HMM-score: 11.3)
    P-loop_NTPase (CL0023) AAA_23; AAA domain (PF13476; HMM-score: 10.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.8829
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.1166
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.021251
    • TAT(Tat/SPI): 0.000413
    • LIPO(Sec/SPII): 0.036865
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000642279 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLLQETLDFVKEENGSAETETKLVEELKAILDKLK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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