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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NU83127
  • locus tag: EL277_RS08995 [old locus tag: SPNU_1703 ]
  • pan locus tag?: PNEUPAN003281000
  • symbol: EL277_RS08995
  • pan gene symbol?: Int-Tn_2
  • synonym:
  • product: tyrosine-type recombinase/integrase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL277_RS08995 [old locus tag: SPNU_1703 ]
  • symbol: EL277_RS08995
  • product: tyrosine-type recombinase/integrase
  • replicon: chromosome
  • strand: -
  • coordinates: 1710288..1711415
  • length: 1128
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018936 (1710288..1711415) NCBI
  • BioCyc: EL277_RS08995 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGCTTATATCGAGTATAAACAGCGTGGGAAGAAAAGGCTTTGGTCGTTCTCTATACGT
    GAGAGGAGCAAGAGCCTACTCCATAAAAGCGGATTTAAAACAAAACGAGAAGCTAAAATA
    GAAGCTGAGAAGGTGCTTCATAAGTTAAACACAGGAAGTATTTTGCATTCTAATATGACT
    TTATCGGAACTTTATCAAGAATGGCTTGATTTGAAAATTTTACCTAGTAGTAGAAGTGAG
    GTCACAAAAAAGAAATATCTCATGAGAAAAAATGTTATTAAAAGGCTATTTGGAGATAAA
    CCTGTATCACAAATTAAGCCTAGCGAGTATCAAAAAATCATGAATGAGTATGGTAGAAGT
    GTTTCAAGAAACTTTCTGGGTAGATTGAATTCTGGGATTCGTGCAAGTATACAGATGGCT
    ATTGCTGATAAAGTAGTGATAGAAGATTTTACTGCTTATGTAGATTTGTTTTCAATTAAG
    AGTGGACAAAAGGTTGAAGAAAAGTATTTACATACTGAAGCTGACTACCAAAAAGTCTTA
    GTGTATTTGAAAAATAAGTTTGATTATCAGAAATCTATTGTACCGTATGTAATTTATTTC
    CTTTTTAAAACTGGCATGCGTTTCTCCGAATTGATTGCTCTAACTTGGGATGAAGTTGAC
    GAGCTTAATGAGCAACTTAAAACTTATCGTCGTTACAACACCGCTATTCATAAGTTTACT
    CCACCTAAAAACAATACTTCAATAAGATTAGTTCCTATTACTTCAGATATGCTTTCCTTG
    TTAAAAACATTGAAAATATTGCAATTAAAAACAAATAAAGAATTAAATATTGATAATGAA
    AATAATTTGATTTTTCAGCATTTTGGGTATACCTACGATGTTCCAGATATTGCAACAGTC
    AATAAAGCTATAAAAGTAATGTTGAAGGAATTGCAAATTTCTCCATTGATTACTACCAAA
    GGAGCTAGACACACTTATGGTAGTTATTTATGGCATAATAATATTGATTTGGGAGTTATT
    GCGAAAATTTTAGGACACAAAGATATCTCTATGCTGGTTGAAGTTTATGGTCACACATTG
    GAGGAAAAAATTAGTGAGGAATTCGTGGCTGTGAAAAGTTTGTTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1128

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL277_RS08995 [old locus tag: SPNU_1703 ]
  • symbol: EL277_RS08995
  • description: tyrosine-type recombinase/integrase
  • length: 375
  • theoretical pI: 10.1315
  • theoretical MW: 43692.6
  • GRAVY: -0.355467

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 47.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 39.4)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 23.6)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 23.6)
  • TheSEED:
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 72)
    and 2 more
    MBD-like (CL0081) Arm-DNA-bind_4; Arm DNA-binding domain (PF14657; HMM-score: 25.2)
    l-integrase_N (CL0469) Phage_int_SAM_3; Phage integrase, N-terminal SAM-like domain (PF14659; HMM-score: 25.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9664
    • Cytoplasmic Membrane Score: 0.015
    • Cell wall & surface Score: 0.0027
    • Extracellular Score: 0.0159
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004583
    • TAT(Tat/SPI): 0.000427
    • LIPO(Sec/SPII): 0.001785
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_126443150 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MAYIEYKQRGKKRLWSFSIRERSKSLLHKSGFKTKREAKIEAEKVLHKLNTGSILHSNMTLSELYQEWLDLKILPSSRSEVTKKKYLMRKNVIKRLFGDKPVSQIKPSEYQKIMNEYGRSVSRNFLGRLNSGIRASIQMAIADKVVIEDFTAYVDLFSIKSGQKVEEKYLHTEADYQKVLVYLKNKFDYQKSIVPYVIYFLFKTGMRFSELIALTWDEVDELNEQLKTYRRYNTAIHKFTPPKNNTSIRLVPITSDMLSLLKTLKILQLKTNKELNIDNENNLIFQHFGYTYDVPDIATVNKAIKVMLKELQISPLITTKGARHTYGSYLWHNNIDLGVIAKILGHKDISMLVEVYGHTLEEKISEEFVAVKSLL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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