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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: EL334_RS01040 [old locus tag: ASP0581_01870 ]
  • pan locus tag?: PNEUPAN000917000
  • symbol: uvrA
  • pan gene symbol?: uvrA
  • synonym:
  • product: excinuclease ABC subunit UvrA

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL334_RS01040 [old locus tag: ASP0581_01870 ]
  • symbol: uvrA
  • product: excinuclease ABC subunit UvrA
  • replicon: chromosome
  • strand: +
  • coordinates: 185188..188019
  • length: 2832
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP019192 (185188..188019) NCBI
  • BioCyc: EL334_RS01040 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0176 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    ATGCAAGATAAAATTGTCATTCATGGGGCGCGTGCCCATAATTTAAAAAATATTGATGTG
    GAGATTCCGCGAGACAAGTTGGTTGTCGTGACTGGCTTGTCAGGTTCAGGGAAGTCCAGT
    CTGGCTTTTGATACTCTCTATGCGGAGGGACAACGTCGCTATGTAGAGAGTTTGTCTGCC
    TACGCTCGTCAGTTCTTGGGAAATATGGAAAAACCAGATGTAGATGCCATTGATGGTCTC
    AGCCCAGCTATTTCCATCGACCAGAAAACGACTAGTAAAAATCCTCGCTCGACGGTGGGA
    ACGACGACTGAAATCAATGACTATCTGCGTCTCCTCTACGCACGTGTGGGGACGCCTTAC
    TGTATCAACGGACATGGAGCTATCAATGCTTCTTCTGTGGAGCAAATCGTTGATAAGGTT
    TTGGAGTTACCTGAACGCCAGCGCTTGCAGATCTTGGCTCCTGTCATCCGCAAGAAAAAA
    GGCCAACATAAGAGTGTTATCGAGAAGGTTCAGAAAGACGGGTATGTTCGTGTTCGTGTG
    GATGGGGAAGTCTATGATGTGACCGAAGTGCCAGAGTTGTCTAAGAGCAAGCAACACAAT
    ATCGATGTCGTGGTTGACCGTATTGTTATCAAGGAGGGCATTCGTAGCCGTCTCTTTGAT
    TCCATTGAAGCTGCCCTTCGTATCGCAGAAGGTTATGTGATTATCGACACCATGGACGAC
    TCTGAGTTGTTGTTCTCTGAGCATTATGCCTGTCCAGTTTGTGGATTTACTGTCCCAGAG
    TTAGAACCTCGTCTCTTCTCTTTCAATGCTCCCTTTGGCTCTTGTAGTGAGTGTGACGGC
    TTGGGGATTAAGCTGGAGGTGGATACTGATTTGGTAGTGCCAGATGCCAGCAAAACCTTA
    CATGAGGGAGCGCTGGCACCTTGGAATCCTATCTCATCCAACTACTATCCAAACATGTTA
    GAGCAGGCCATGAAAGTCTTTGGAGTGGCTATGGATAAGCCTTTTGAGGACCTGTCAGAA
    GAAGATAAGAACTTGATTCTCTACGGCTCAGATGGTAAGGAATTCCATTTCCATTATGAA
    AATGAATTTGGTGGTGTGCGCGATATCGACATTCCGTTTGAGGGAGTTATCAATAATATC
    AAACGTCGTTACCATGAAACCAATAGCGATTACACTCGCACTCAGATGCGTCTCTACATG
    AATGAGCTGACCTGCGGAACCTGTCAAGGCTATCGTCTCAATGACCAGGCCTTGTCTGTC
    CGTGTGGGCGGCCAGCAAGGGCCACATATTGGAGAAATCTCAGACCTGTCTATCGCTGAC
    CACTTGGACTTGGTGAGCCAGTTAACTTTGTCTGAAAATGAAGCCATCATTGCTCGTCCC
    ATTCTCAAGGAAATCAAGGATCGTTTGACCTTCCTTAATAATGTGGGTCTTAACTATCTA
    ACCCTGTCACGTTCAGCAGGAACCCTTTCAGGTGGGGAAAGTCAGCGCATTCGTTTGGCA
    ACCCAGATTGGTTCCAACCTATCAGGTGTCCTCTATATCCTAGACGAGCCGTCAATCGGT
    CTTCACCAGAGGGACAATGACCGCCTGATTGCCAGTCTGAAAAAGATGCGTGACTTGGGC
    AATACTCTTATCGTGGTGGAACACGACGAAGATACCATGCGTGAAGCTGATTATCTGATT
    GACGTTGGTCCTGGTGCCGGTGTTTTTGGTGGTGAGATTGTTGCAGCAGGTACACCTAAG
    CAAGTGGCTCGCAACAGCAAGTCTATCACAGGTCAGTACTTGTCAGGCAAACGTGTCATC
    CCAGTACCAGAAGAGCGCCGTGTCGGAAATGGTCGTTTTATTGAAGTGACAGGAGCGCGT
    GAGAACAACTTGCAAAATGTCACGGCTCGCTTTCCACTAGGAAAATTTATCGCAGTGACA
    GGTGTGTCGGGTTCAGGGAAATCGACTCTAATCAACAGCATTCTCAAAAAAGCCATTGCC
    CAGAAGCTCAACCGTAATTCAGACAAACCTGGTAAGTTTAAGACTATTACAGGGATTGAG
    CATGTCGACCGTTTGATTGATATTGACCAGAGCCCTATCGGACGGACGCCGAGGTCTAAC
    CCAGCTACCTATACAGGAGTTTTTGACGATATACGTGACCTTTTTGCTCAGACAAATGAA
    GCCAAGATTCGAGGCTACAAGAAGGGGCGCTTCAGTTTCAACGTCAAGGGAGGTCGCTGT
    GAAGCTTGCTCAGGTGACGGGATTATCAAGATTGAGATGCACTTCTTGCCAGATGTTTAT
    GTGGCTTGTGAAGTTTGCCACGGAACCCGCTATAACAGTGAAACCCTAGAAGTTCACTAC
    AAGGAAAAGAATATTTCGCAGGTCTTGGATATGACGGTCAACGATGCGGTAGAATTTTTC
    CAACACATTCCGAAAATTCAACGCAAACTCCAGACCATCAAGGATGTAGGGCTAGGCTAT
    GTGACCTTGGGACAGCCAGCTACCACCCTTTCTGGGGGAGAAGCCCAACGTATGAAGTTA
    GCTAGCGAACTCCACAAACGCTCGATAGGAAAATCTTTCTACATTCTGGATGAGCCGACG
    ACAGGGCTTCATACAGAGGACATTGCTCGCCTGCTCAAGGTTTTAGCTCGCTTTGTAGAC
    GATGGCAATACAGTCCTCGTCATCGAGCACAATCTGGATGTTATCAAGACGGCAGACCAT
    ATCATTGACTTGGGACCTGAGGGTGGTGTCGGTGGTGGAACCATCATCGTAACAGGAACT
    CCAGAAGAAGTAGCTGCCAACGAAGCCAGCTATACAGGACATTATTTGAAAGGAAAGTTA
    CATCATGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2832

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL334_RS01040 [old locus tag: ASP0581_01870 ]
  • symbol: UvrA
  • description: excinuclease ABC subunit UvrA
  • length: 943
  • theoretical pI: 6.33233
  • theoretical MW: 104166
  • GRAVY: -0.302121

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.25.-?  ExPASy
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair excinuclease ABC subunit A (TIGR00630; EC 3.1.25.-; HMM-score: 1452.2)
    and 99 more
    Cellular processes Cellular processes Toxin production and resistance putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 125.8)
    Metabolism Transport and binding proteins Unknown substrate putative bacteriocin export ABC transporter, lactococcin 972 group (TIGR03608; HMM-score: 125.8)
    thiol reductant ABC exporter, CydD subunit (TIGR02857; HMM-score: 122.3)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 121.7)
    Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 108.8)
    Cellular processes Cellular processes Cell division cell division ATP-binding protein FtsE (TIGR02673; HMM-score: 104.7)
    proposed F420-0 ABC transporter, ATP-binding protein (TIGR03873; HMM-score: 94.3)
    Metabolism Transport and binding proteins Anions phosphonate ABC transporter, ATP-binding protein (TIGR02315; EC 3.6.3.28; HMM-score: 90.1)
    thiol reductant ABC exporter, CydC subunit (TIGR02868; HMM-score: 87)
    Metabolism Transport and binding proteins Cations and iron carrying compounds cobalt ABC transporter, ATP-binding protein (TIGR01166; HMM-score: 86)
    Metabolism Transport and binding proteins Anions phosphate ABC transporter, ATP-binding protein (TIGR00972; EC 3.6.3.27; HMM-score: 81.7)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01842; HMM-score: 81.4)
    phosphonate C-P lyase system protein PhnL (TIGR02324; HMM-score: 80.6)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 75)
    Metabolism Transport and binding proteins Other lipid A export permease/ATP-binding protein MsbA (TIGR02203; HMM-score: 75)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtD (TIGR03411; HMM-score: 74.7)
    ABC exporter ATP-binding subunit, DevA family (TIGR02982; HMM-score: 74.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, ATP-binding protein (TIGR02211; EC 3.6.3.-; HMM-score: 72.4)
    Metabolism Transport and binding proteins Other pigment precursor permease (TIGR00955; HMM-score: 71.7)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 69.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 69.5)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 68.4)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikD (TIGR02770; HMM-score: 68.3)
    Metabolism Transport and binding proteins Unknown substrate anchored repeat-type ABC transporter, ATP-binding subunit (TIGR03771; HMM-score: 68.3)
    Metabolism Transport and binding proteins Other daunorubicin resistance ABC transporter, ATP-binding protein (TIGR01188; HMM-score: 67.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 67.6)
    Metabolism Transport and binding proteins Other heme ABC exporter, ATP-binding protein CcmA (TIGR01189; EC 3.6.3.41; HMM-score: 67.6)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 65.9)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 65.9)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 65.9)
    Metabolism Transport and binding proteins Anions sulfate ABC transporter, ATP-binding protein (TIGR00968; EC 3.6.3.25; HMM-score: 63.5)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 61.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 61.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines glycine betaine/L-proline transport ATP binding subunit (TIGR01186; HMM-score: 61)
    Metabolism Transport and binding proteins Amino acids, peptides and amines urea ABC transporter, ATP-binding protein UrtE (TIGR03410; HMM-score: 59.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system (TIGR03864; HMM-score: 58.8)
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 57.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, ATP-binding protein (TIGR03797; HMM-score: 57.1)
    Metabolism Transport and binding proteins Amino acids, peptides and amines putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein (TIGR03265; HMM-score: 56.9)
    D-methionine ABC transporter, ATP-binding protein (TIGR02314; EC 3.6.3.-; HMM-score: 56.7)
    Metabolism Transport and binding proteins Cations and iron carrying compounds nickel import ATP-binding protein NikE (TIGR02769; EC 3.6.3.24; HMM-score: 56.7)
    ABC transporter, permease/ATP-binding protein (TIGR02204; HMM-score: 55.1)
    Metabolism Transport and binding proteins Anions molybdate ABC transporter, ATP-binding protein (TIGR02142; EC 3.6.3.29; HMM-score: 53.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS assembly ATPase SufC (TIGR01978; HMM-score: 51.5)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 51.2)
    Metabolism Transport and binding proteins Other LPS export ABC transporter ATP-binding protein (TIGR04406; HMM-score: 51.2)
    Metabolism Transport and binding proteins Anions nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 50.8)
    Metabolism Transport and binding proteins Other nitrate ABC transporter, ATP-binding proteins C and D (TIGR01184; HMM-score: 50.8)
    Metabolism Transport and binding proteins Other thiamine ABC transporter, ATP-binding protein (TIGR01277; EC 3.6.3.-; HMM-score: 50)
    Metabolism Energy metabolism Methanogenesis methyl coenzyme M reductase system, component A2 (TIGR03269; HMM-score: 49.8)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids glucan exporter ATP-binding protein (TIGR01192; EC 3.6.3.42; HMM-score: 48.6)
    ATP-binding cassette protein, ChvD family (TIGR03719; HMM-score: 45.9)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate C-P lyase system protein PhnK (TIGR02323; HMM-score: 44.9)
    Metabolism Transport and binding proteins Amino acids, peptides and amines choline ABC transporter, ATP-binding protein (TIGR03415; HMM-score: 43.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids D-xylose ABC transporter, ATP-binding protein (TIGR02633; EC 3.6.3.17; HMM-score: 42.5)
    lantibiotic protection ABC transporter, ATP-binding subunit (TIGR03740; HMM-score: 41.5)
    Metabolism Transport and binding proteins Other antigen peptide transporter 2 (TIGR00958; HMM-score: 36.7)
    2-aminoethylphosphonate ABC transport system, ATP-binding component PhnT (TIGR03258; HMM-score: 36)
    ectoine/hydroxyectoine ABC transporter, ATP-binding protein EhuA (TIGR03005; HMM-score: 35.3)
    Metabolism Transport and binding proteins Amino acids, peptides and amines polyamine ABC transporter, ATP-binding protein (TIGR01187; EC 3.6.3.31; HMM-score: 33.9)
    Cellular processes Cellular processes Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 33.2)
    Metabolism Transport and binding proteins Other nodulation ABC transporter NodI (TIGR01288; HMM-score: 33.2)
    gliding motility-associated ABC transporter ATP-binding subunit GldA (TIGR03522; HMM-score: 32.9)
    Metabolism Transport and binding proteins Other pleiotropic drug resistance family protein (TIGR00956; HMM-score: 23.6)
    Metabolism Transport and binding proteins Anions cystic fibrosis transmembrane conductor regulator (CFTR) (TIGR01271; EC 3.6.3.49; HMM-score: 23)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 22.8)
    Genetic information processing Protein synthesis Translation factors ribosome small subunit-dependent GTPase A (TIGR00157; EC 3.6.-.-; HMM-score: 21.6)
    Metabolism Central intermediary metabolism Sulfur metabolism adenylyl-sulfate kinase (TIGR00455; EC 2.7.1.25; HMM-score: 19.5)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions dTMP kinase (TIGR00041; EC 2.7.4.9; HMM-score: 18.8)
    HprK-related kinase B (TIGR04355; HMM-score: 18.6)
    Metabolism Transport and binding proteins Other multi drug resistance-associated protein (MRP) (TIGR00957; HMM-score: 18.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Nucleotide and nucleoside interconversions guanylate kinase (TIGR03263; EC 2.7.4.8; HMM-score: 18.1)
    Dot/Icm secretion system ATPase DotB (TIGR02524; HMM-score: 18)
    Metabolism Central intermediary metabolism Phosphorus compounds phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN (TIGR02322; HMM-score: 17)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion protein EccCb (TIGR03925; HMM-score: 15.9)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair exonuclease SbcC (TIGR00618; HMM-score: 14.6)
    Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 14.5)
    Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 14.5)
    Metabolism Transport and binding proteins Amino acids, peptides and amines cyclic peptide transporter (TIGR01194; HMM-score: 14.5)
    Metabolism Transport and binding proteins Other cyclic peptide transporter (TIGR01194; HMM-score: 14.5)
    Cell structure Cell envelope Surface structures twitching motility protein (TIGR01420; HMM-score: 13.9)
    Cellular processes Cellular processes Chemotaxis and motility twitching motility protein (TIGR01420; HMM-score: 13.9)
    Unknown function General small GTP-binding protein domain (TIGR00231; HMM-score: 13.7)
    KaiC domain protein, PAE1156 family (TIGR03881; HMM-score: 13.6)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 13.5)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTP-binding protein YlqF (TIGR03596; HMM-score: 13.5)
    Genetic information processing Protein synthesis tRNA and rRNA base modification tRNA threonylcarbamoyl adenosine modification protein YjeE (TIGR00150; HMM-score: 13.1)
    Cellular processes Cellular processes Pathogenesis type II secretion system protein E (TIGR02533; HMM-score: 12.9)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type II secretion system protein E (TIGR02533; HMM-score: 12.9)
    Genetic information processing Protein synthesis Other GTP-binding protein Era (TIGR00436; HMM-score: 12.7)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DnaA regulatory inactivator Hda (TIGR03420; HMM-score: 12.5)
    Genetic information processing Protein synthesis Other ribosome biogenesis GTPase YqeH (TIGR03597; HMM-score: 12.3)
    Metabolism Transport and binding proteins Other rim ABC transporter (TIGR01257; HMM-score: 12.2)
    carbohydrate kinase, thermoresistant glucokinase family (TIGR01313; EC 2.7.1.-; HMM-score: 12.1)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking putative secretion ATPase, PEP-CTERM locus subfamily (TIGR03015; HMM-score: 11.9)
    Genetic information processing Transcription RNA processing polynucleotide kinase-phosphatase (TIGR04075; HMM-score: 11.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids peroxysomal long chain fatty acyl transporter (TIGR00954; HMM-score: 11.2)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Molybdopterin molybdopterin-guanine dinucleotide biosynthesis protein B (TIGR00176; HMM-score: 10.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pantothenate and coenzyme A dephospho-CoA kinase (TIGR00152; EC 2.7.1.24; HMM-score: 9.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined UvrA_inter; UvrA interaction domain (PF17760; HMM-score: 134.3)
    UvrA_DNA-bind; UvrA DNA-binding domain (PF17755; HMM-score: 125.6)
    and 43 more
    P-loop_NTPase (CL0023) ABC_tran; ABC transporter (PF00005; HMM-score: 83.3)
    SMC_N; RecF/RecN/SMC N terminal domain (PF02463; HMM-score: 51.8)
    AAA_16; AAA ATPase domain (PF13191; HMM-score: 40.4)
    AAA_29; P-loop containing region of AAA domain (PF13555; HMM-score: 31.9)
    RsgA_GTPase; RsgA GTPase (PF03193; HMM-score: 31.5)
    AAA_22; AAA domain (PF13401; HMM-score: 27.3)
    AAA_33; AAA domain (PF13671; HMM-score: 26)
    AAA_21; AAA domain, putative AbiEii toxin, Type IV TA system (PF13304; HMM-score: 24.7)
    AAA_23; AAA domain (PF13476; HMM-score: 24.5)
    AAA_18; AAA domain (PF13238; HMM-score: 23.5)
    MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 23.1)
    AAA_25; AAA domain (PF13481; HMM-score: 21.5)
    Viral_helicase1; Viral (Superfamily 1) RNA helicase (PF01443; HMM-score: 21.4)
    AAA_14; AAA domain (PF13173; HMM-score: 20.6)
    APS_kinase; Adenylylsulphate kinase (PF01583; HMM-score: 20.2)
    ATPase; KaiC (PF06745; HMM-score: 19.5)
    DUF2075; Schlafen group 3, DNA/RNA helicase domain (PF09848; HMM-score: 19.5)
    NACHT; NACHT domain (PF05729; HMM-score: 19.4)
    T2SSE; Type II/IV secretion system protein (PF00437; HMM-score: 18)
    cobW; CobW/HypB/UreG, nucleotide-binding domain (PF02492; HMM-score: 17.8)
    DUF87; Helicase HerA, central domain (PF01935; HMM-score: 17.3)
    no clan defined DnaJ_CXXCXGXG; DnaJ central domain (PF00684; HMM-score: 16.8)
    RACo_linker; RACo linker region (PF17650; HMM-score: 16.6)
    P-loop_NTPase (CL0023) AAA_24; AAA domain (PF13479; HMM-score: 16.3)
    NB-ARC; NB-ARC domain (PF00931; HMM-score: 16.1)
    AAA_30; AAA domain (PF13604; HMM-score: 15.6)
    ATPase_2; ATPase domain predominantly from Archaea (PF01637; HMM-score: 15.4)
    MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 15.4)
    Septin; Septin (PF00735; HMM-score: 15.1)
    RNA_helicase; RNA helicase (PF00910; HMM-score: 15.1)
    BCA_ABC_TP_C; Branched-chain amino acid ATP-binding cassette transporter (PF12399; HMM-score: 15)
    PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 14.9)
    IIGP; Interferon-inducible GTPase (IIGP) (PF05049; HMM-score: 14.5)
    Dynamin_N; Dynamin family (PF00350; HMM-score: 13.9)
    C2H2-zf (CL0361) SF3a60_Prp9_C; SF3a60/Prp9 C-terminal (PF11931; HMM-score: 13.9)
    P-loop_NTPase (CL0023) AAA_7; P-loop containing dynein motor region (PF12775; HMM-score: 13.9)
    Glutaminase_I (CL0014) DUF4350; Domain of unknown function (DUF4350) (PF14258; HMM-score: 12.8)
    P-loop_NTPase (CL0023) Zeta_toxin; Zeta toxin (PF06414; HMM-score: 12.6)
    DUF463; YcjX-like family, DUF463 (PF04317; HMM-score: 12.3)
    AAA_28; AAA domain (PF13521; HMM-score: 12.1)
    NTPase_1; NTPase (PF03266; HMM-score: 11.9)
    SbcC_Walker_B; SbcC/RAD50-like, Walker B motif (PF13558; HMM-score: 11.2)
    RING (CL0229) FANCL_C; FANCL C-terminal domain (PF11793; HMM-score: 10.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7867
    • Cytoplasmic Membrane Score: 0.1634
    • Cell wall & surface Score: 0.0025
    • Extracellular Score: 0.0474
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.012676
    • TAT(Tat/SPI): 0.012451
    • LIPO(Sec/SPII): 0.001528
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_126432041 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTTTEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKKGQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRLFDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCSECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKPFEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYTRTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTLSENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLSGVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGAGVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNLQNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHVDRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVEFFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSIGKSFYILDEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIIVTGTPEEVAANEASYTGHYLKGKLHHE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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