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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: EL334_RS03940 [old locus tag: ASP0581_07370 ]
  • pan locus tag?: PNEUPAN001748000
  • symbol: EL334_RS03940
  • pan gene symbol?: pepN
  • synonym:
  • product: M1 family metallopeptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL334_RS03940 [old locus tag: ASP0581_07370 ]
  • symbol: EL334_RS03940
  • product: M1 family metallopeptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 736692..739238
  • length: 2547
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP019192 (736692..739238) NCBI
  • BioCyc: EL334_RS03940 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0700 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    ATGCAAGCAGTTGAACATTTTATTAAGCAATTTGTTCCTGAACATTATGATTTATTTTTA
    GATTTGAGTCGTGAGACCAAGACTTTTTCTGGGAAAGTGACCATCACTGGTCAAGCACAG
    AGTGACCGCATCTCCCTCCACCAAAAAGACTTGGAAATCACCTCTGTAGAAGTTGCAGGT
    CAAGCTCGTCCATTTACAGTTGACCATGACAATGAAGCCCTTCATATCGAATTGGCTGAG
    GCTGGTCAAGTTGAATTGGTTCTTGCCTTTTCTGGTAAAATTACAGACAACATGACAGGG
    ATTTACCCTTCTTATTATACAGTTGATGGAGTCAAGAAGGAGGTCTTGTCTACTCAGTTC
    GAGAGCCATTTTGCGCGCGAAGCTTTCCCATGTGTGGATGAGCCTGAAGCCAAAGCAACT
    TTTGACCTCTCTCTTCGCTTTGACCAAGCAGAAGGTGAATTGGCCTTGTCAAACATGCCA
    GAAATCGATGTTGAAAACCGTAAGGAAACAGGTATCTGGAAGTTTGAGACAACACCTCGC
    ATGTCTTCTTACTTGTTGGCCTTTGTTGCTGGTGATTTGCAAGGGGTGACCGCTAAAACT
    AAAAATGGTACCCTGGTAGGTGTCTACTCAACCAAAGCACATCCACTTTCAAATCTTGAT
    TTCTCACTGGATATCGCTGTTCGCTCTATCGAGTTTTACGAAGATTACTATGGAGTTAAG
    TACCCAATTCCTCAATCTCTCCACATCGCCCTTCCTGACTTCTCAGCTGGTGCTATGGAA
    AACTGGGGTCTTGTGACCTACCGTGAAGTTTACTTGGTTGTCGATGAGAACTCTACATTT
    GCTAGCCGTCAACAAGTTGCCCTTGTTGTGGCCCATGAATTGGCTCACCAATGGTTTGGG
    AACCTCGTGACTATGAAATGGTGGGATGACCTTTGGCTCAATGAAAGTTTCGCTAATATG
    ATGGAATACGTCTGTGTGGATACCATCGAACCAAGCTGGAATATCTTTGAAGATTTCCAA
    ACAGGTGGAGTACCTCTTGCTCTTGAACGTGACGCTACTGATGGCGTTCAGTCTGTCCAC
    GTCGAAGTTAAACATCCAGATGAAATCAATACACTCTTTGACGGCGCTATCGTCTATGCC
    AAAGGAAGCCGTCTCATGCACATGCTTCGCCGTTGGCTAGGAGATGCTGATTTTGCTAAA
    GGTTTGCACGCCTACTTTGAAAAACACCAATACAGCAACACCATTGGTAGTGACCTTTGG
    GATGCCCTTGGTCAAGCGTCAGGACGTGATGTCGCAGCCTTCATGGATTCTTGGTTGGAA
    CAGCCTGGTTACCCAGTTCTTACTGTCAAAGTTGAAAATGATGTCTTGAAGATTTCACAA
    AAACAATTCTTCATCGGTGAGAACGAAGACAAGAACCGTCTCTGGGTGGTGCCCCTCAAT
    AGCAACTGGAAAGGCTTGCCTGATACACTCGAAACTGAAAGTATCGAAATCCCTGGCTAC
    GCAGCTCTTCTTGCTGAGAATGAAGGAGCTCTTCGTCTCAACACTGAAAATACTGCCCAC
    TATATTACCGACTATCAAGGAGACTTGTTAGAAGCTGTTCTTGCTGAGCTAGAGACACTT
    GATAACACAAGCAAACTGCAAATTGTTCAAGAACGTCGTTTGTTGGCTGAGGCAGGGCAC
    ATTTCTTATGCAGACTTGCTTCCAGTTCTTGATAAACTTGCTAAGGAAGAGTCTTATCTG
    GTGGTTTCAGCTGTTTCTCAAGTGATTTCAGCCCTTGAGCGCTTTATTGATGAAGGAACG
    GATGCTGAAACAGCCTTCAAAGGACTGGTTGCTAAATTGGCTCGTCATAACTATGGCCGT
    CTTGGTTTTGAAGCTAAAGACGGAGAATCAGATGAGGATGAATTGGTTCGTCAGCTGGCT
    GTTTCGATGATGATTCTCTCAAATGATGCAGAAGCTAGTCAAGTCGCTAGCCAAATCTTC
    GCAACACACAAGGAGAATCTTGCAGGACTCCCAGCAGCTATTCGTTCACAAGTTCTGATT
    AATGAGATGAAACATCATGAGACTAAAGACTTGTTAGCACTTTATCTTGATACTTATACT
    CACGCAACAGATGCTGTCTTTAAACGCCAGTTGGCAGCAGCTCTTGCATACAGTACAGAT
    GCGGATAATATCCAAAACTTGATTACTTCTTGGAAGGACAAATTTGTGGTCAAACCACAG
    GACTTGTCTGCTTGGTATTACCAATTCCTAGCTCATCAAGCAACTCAGAAAACAGCTTGG
    TCTTGGGCGCGTGAAAACTGGGCTTGGATTAAGGCAGCCCTTGGAGGAGATATGAGCTTT
    GATAGCTTTGTTATCCTTCCTGCTCATGTATTTAAGACTCAGCAACGCTTGGCGGAATAC
    AAGGAGTTCTTTGAGCCGCAACTTTCTGACCTTGCTCTTAGCCGTAACATCGGTATGGGA
    ATCAAGGAAATTGCAGCGCGTGTTGACTTGATTAGCCGTGAAAAAGCTGCAGTCGAGGCA
    GTTGTTCTTCAATACGGAAATGCATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2547

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL334_RS03940 [old locus tag: ASP0581_07370 ]
  • symbol: EL334_RS03940
  • description: M1 family metallopeptidase
  • length: 848
  • theoretical pI: 4.53698
  • theoretical MW: 95248.6
  • GRAVY: -0.198467

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.11.-?  ExPASy
  • TIGRFAM:
    aminopeptidase N (TIGR02412; EC 3.4.11.2; HMM-score: 302.2)
    and 2 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides aminopeptidase N (TIGR02414; EC 3.4.11.2; HMM-score: 144.3)
    leukotriene A-4 hydrolase/aminopeptidase (TIGR02411; EC 3.3.2.6,3.4.11.-; HMM-score: 110.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Peptidase_MA (CL0126) Peptidase_M1; Peptidase family M1 domain (PF01433; HMM-score: 278.9)
    and 3 more
    p35 (CL0672) Peptidase_M1_N; Peptidase M1 N-terminal domain (PF17900; HMM-score: 170.5)
    E-set (CL0159) ERAP1_C; ERAP1-like C-terminal domain (PF11838; HMM-score: 136.7)
    no clan defined DUF4936; Domain of unknown function (DUF4936) (PF16290; HMM-score: 18.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9401
    • Cytoplasmic Membrane Score: 0.0032
    • Cell wall & surface Score: 0.0016
    • Extracellular Score: 0.0551
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00331
    • TAT(Tat/SPI): 0.001061
    • LIPO(Sec/SPII): 0.000385
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_033705190 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRISLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIYPSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMPEIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSNLDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDENSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWNIFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRWLGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVKVENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENEGALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADLLPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYGRLGFEAKDGESDEDELVRQLAVSMMILSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINEMKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQDLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLAEYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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