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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: EL334_RS10905 [old locus tag: ASP0581_20140 ]
  • pan locus tag?: PNEUPAN003756000
  • symbol: EL334_RS10905
  • pan gene symbol?: —
  • synonym:
  • product: helix-turn-helix domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL334_RS10905 [old locus tag: ASP0581_20140 ]
  • symbol: EL334_RS10905
  • product: helix-turn-helix domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1992183..1992665
  • length: 483
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP019192 (1992183..1992665) NCBI
  • BioCyc: EL334_RS10905 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1916 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGCTTATAATAGAGGTAAACAACTCAGGAAGTTCTTGTAGGTTGCGAGAGTTTGGCGAA
    AAAATTAAAAGATTACGTTTGGCTAAAAAAATCAGTCGTTCAGAATTTTGTGGTGATGAG
    TCTGAATTAAGTATCCGTCAATTAATTAGAATTGAAAATGGAGAATCCAGACCAACACTA
    ACAAAGTTAAAATATATTGCTGAACGTTTGGAGGTTGAAGATTACAAGTTGATGCCAAGT
    TATATAGAGTTGGATAAGGAATACCTAGAATTGAAGTATTTCTTGATGAGGACTCCTACA
    TACGAAGATGAAACTATCGCCCAAAAGAAAGAGAGTGTTTTTGATAAGATTTTTGAAGAG
    TATTATGATAGGCTACCTGAGGAAGAAAGATTTATCATCCCAAATTATTCATATCTAGCA
    CTAGCGAACTACACAGTTCAAAAATTACCAGAAAAGCTAGTTGAAATACTGTCCTTCTGG
    TGA
    60
    120
    180
    240
    300
    360
    420
    480
    483

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL334_RS10905 [old locus tag: ASP0581_20140 ]
  • symbol: EL334_RS10905
  • description: helix-turn-helix domain-containing protein
  • length: 160
  • theoretical pI: 4.88422
  • theoretical MW: 19203
  • GRAVY: -0.515625

⊟Function[edit | edit source]

  • TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 13.4)
  • TheSEED: data available for D39, TIGR4
  • PFAM:
    TPR (CL0020) ComR_TPR; ComR tetratricopeptide (PF18710; HMM-score: 59.3)
    and 3 more
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 27)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 25.5)
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 17.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.3299
    • Cytoplasmic Membrane Score: 0.45
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.2196
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004472
    • TAT(Tat/SPI): 0.000576
    • LIPO(Sec/SPII): 0.002872
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_155457965 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLIIEVNNSGSSCRLREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRPTLTKLKYIAERLEVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVFDKIFEEYYDRLPEEERFIIPNYSYLALANYTVQKLPEKLVEILSFW

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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