PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 09-MAY-2015

⊟Summary

• organism: Streptococcus pneumoniae NCTC7465
• locus tag: ERS445053_00344 [new locus tag: AT689_RS01725 ]
• pan locus tag^?: PNEUPAN000806000
• symbol: ERS445053_00344
• pan gene symbol^?: —
• synonym:
• product: IS1193%2C transposase%2C ISL3 family

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: ERS445053_00344 [new locus tag: AT689_RS01725 ]
• symbol: ERS445053_00344
• product: IS1193%2C transposase%2C ISL3 family
• replicon: chromosome
• strand: +
• coordinates: 330982..331911
• length: 930
• essential: unknown

⊟Accession numbers

• Location: LN831051 (330982..331911) NCBI
• BioCyc: see AT689_RS01725
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  
  ATGGAACAACTTAAGAATACCACAGATTTGCTCGGATTGGAAGACAAAAATATCAAAATC
  TTGTCTGTTCTGAAATACCAAACCCATCTAGTCGTTCAGGCAAAGTTGGATTCCCCCGCT
  TCTCCTTGTCCTCATTGTCAAGGGAAGATGATCAAATACGACTTCCAGAAAGCCTCTAAA
  ATTCCGCTTCTCGACTGTCAGGGTTTACCCACGGTACTGCATCTCAAAAAGCGCCGCTTT
  CAGTGCAAGAATTGCCTTAAGGTGGTCGTTTCTCAAACATCCATTGTCAAGAAAAATTGC
  CAGATTTCCAACATGGTGAGACAAAAAATCGCTCAGCTCCTCCTTGAAAAGCAGTCTATG
  ACTGAGATTGCCCACAGATTGGCGGGCTCAACTTCCACCGTCATCCGAAAACTGAGGGAA
  TTTAAGTTTGAAACCGATTGGACCAAGTTGCCAAAAGTTATGAGTTGGGATGAGTATAGC
  TTCAAAAAGAGCAAAATGAGCTTCATTGCCCAAGATTTTGAGTCCAAATCCATCCTCGCA
  ATTTTAGACGGACGAACTCATGCGGTGATTCGAAACCATTTCCAACGCTATCAGAGAGAG
  GTTCGGGAGCTGGTCGAGGTCATCACCATGGACATGTACAGCCCTTATTATCGGCTCGCT
  AAGCAACTCTTTCCAAAGGCGAAGATTGTTCTTGACCGCTTCCACATTGTCCAACATCTG
  AGCCGAGCTATGAACCGAGTACGAATCCAAATCATGAACCAATTTGACCGAAAATCCTTG
  GAGTATCGGGCGCTCAAGCGCTTTTGGAACCCTCGCTTTTTCGTTTCTAGGCTCGGGCTA
  AATCAGTCCACTGGACTGATTTACTACACCAGGATAGCTTCAAGCTCTGTCAGAAACGAT
  TCTATCAGCCCACGTTTCGAATGCACTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  930
  

⊟Protein

⊟General

• locus tag: ERS445053_00344 [new locus tag: AT689_RS01725 ]
• symbol: ERS445053_00344
• description: IS1193%2C transposase%2C ISL3 family
• length: 309
• theoretical pI: 10.6262
• theoretical MW: 36259.4
• GRAVY: -0.362783

⊟Function

• TIGRFAM:
  Cellular processes Cellular processes Sporulation and germination RNA polymerase sigma-H factor (TIGR02859; HMM-score: 13.1)
  Genetic information processing Transcription Transcription factors RNA polymerase sigma-H factor (TIGR02859; HMM-score: 13.1)
• TheSEED: data available for Hungary19A-6
• PFAM:
  RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 95.1)
  and 12 more
  Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 41.7)
  HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 37)
  HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 20.2)
  HTH_50; Helix-turn-helix domain (PF18024; HMM-score: 19.6)
  HTH_23; Homeodomain-like domain (PF13384; HMM-score: 15.9)
  Zn_Beta_Ribbon (CL0167) Zn_Tnp_IS1595; Transposase zinc-ribbon domain (PF12760; HMM-score: 14.9)
  l-integrase_N (CL0469) Phage_int_SAM_2; Phage integrase, N-terminal (PF12834; HMM-score: 14.4)
  Zn_Beta_Ribbon (CL0167) Ogr_Delta; Ogr/Delta-like zinc finger (PF04606; HMM-score: 13.1)
  Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 12.2)
  Peroxisome (CL0484) Reticulon; Reticulon (PF02453; HMM-score: 12.1)
  HTH (CL0123) Trp_repressor; Trp repressor protein (PF01371; HMM-score: 11.9)
  HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 9)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.7706
  • Cytoplasmic Membrane Score: 0.0263
  • Cell wall & surface Score: 0.0403
  • Extracellular Score: 0.1629
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.034659
  • TAT(Tat/SPI): 0.002388
  • LIPO(Sec/SPII): 0.001886
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: COT03807 NCBI
• UniProt:

⊟Protein sequence

• MEQLKNTTDLLGLEDKNIKILSVLKYQTHLVVQAKLDSPASPCPHCQGKMIKYDFQKASKIPLLDCQGLPTVLHLKKRRFQCKNCLKVVVSQTSIVKKNCQISNMVRQKIAQLLLEKQSMTEIAHRLAGSTSTVIRKLREFKFETDWTKLPKVMSWDEYSFKKSKMSFIAQDFESKSILAILDGRTHAVIRNHFQRYQREVRELVEVITMDMYSPYYRLAKQLFPKAKIVLDRFHIVQHLSRAMNRVRIQIMNQFDRKSLEYRALKRFWNPRFFVSRLGLNQSTGLIYYTRIASSSVRNDSISPRFECT

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications