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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_1028 [new locus tag: HKM25_RS05020 ]
  • pan locus tag?: PNEUPAN000992000
  • symbol: HKM25_1028
  • pan gene symbol?: ltrA
  • synonym:
  • product: group II intron, maturase-specific domain protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_1028 [new locus tag: HKM25_RS05020 ]
  • symbol: HKM25_1028
  • product: group II intron, maturase-specific domain protein
  • replicon: chromosome
  • strand: +
  • coordinates: 985221..986387
  • length: 1167
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (985221..986387) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTCAAAACTGCTAGATAAGATATTATCACGCGAAAATATGCTGGAAGCCTACAATCAA
    GTAAAATCCAATAAAGGCTCAGCTGGGATTGATGGAATGACTATCGAAGAGATGGATAAT
    TATCTCAGACAAAACTGGCGCTTGACTAAGGAACTGATAAAACAGAGAAAATATAAGCCT
    CAACCAGTTCTTAAAGTTGAGATACCTAAACCAGACGGAGGCATCCGTCAACTAGGAATT
    CCAACAGTTATGGATAGAATGATTCAACAGGCCATTGTTCAAGTTATTAGCCCTATTTGT
    GAACCCCATTTCTCAGATACGAGCTATGGATTCAGACCAAATAGGTCATGTGAAAAAGCC
    ATCATGAAGCTCTTAGAGTACTTAAATGACGGCTATGAGTGGATAGTGGACATAGACCTA
    GAGAAATTTTTCGATACAGTTCCTCAAGATAGATTGATGTCCTTAGTACATAACATTATC
    GAAGACGGAGATACGGAATCCTTGATTCGTAAATATCTTCATTCAGGTGTTATCATTAAC
    GGTCAACGTTATAAAACGCTAGTTGGCACGCCACAGGGAGGAAATTTATCTCCTCTCTTA
    TCCAATATCATGCTTAATGAATTGGACAAGGAATTAGAAAAGAGAGGGCTTCGATTTGTT
    CGCTACGCAGACGATTGTGTGATTACGGTCGGAAGCGAGGCAGCCGCTAAGCGTGTGATG
    TATTCAGTCAGTCGTTTTATTGAAAAACGGCTAGGTTTGAAAGTAAACATGACCAAGACT
    AAGATTACCAGACCAAGAGAGTTGAAATATCTAGGTTTTGGGTTCTGGAAATCATCAGAT
    GGTTGGAAAAGTCGTCCACATCAAGATAGTGTTTGGAGATTTAAGCTTAAATTGAAGAAA
    CTAACACAGAGGAAATGGAGTATAGACCTAACAAGACGTATTGAGCAACTGAATTTGTCT
    ATTCGAGGATGGATAAACTATTTCTCATTGGGAAATATGAAAAGTATAGTCACCAGCATA
    GATGAGCGTTTGCATACTCGCCTACGAGTGATTATCTGGAAGCAATGGAAGAAGAAATCG
    AGACGATTATGGGGATTGCTTAAGTTAGGGGTTCCTAAATGGATAGCAGATAAGGTATCT
    GGCTGGGGCGACCACTATCAATTATAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1167

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_1028 [new locus tag: HKM25_RS05020 ]
  • symbol: HKM25_1028
  • description: group II intron, maturase-specific domain protein
  • length: 388
  • theoretical pI: 10.4525
  • theoretical MW: 45346.6
  • GRAVY: -0.473969

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Mobile and extrachromosomal element functions Other group II intron reverse transcriptase/maturase (TIGR04416; EC 2.7.7.49; HMM-score: 420)
    and 1 more
    abortive infection protein, AbiA family (TIGR04499; HMM-score: 24.4)
  • TheSEED:
  • PFAM:
    RdRP (CL0027) RVT_1; Reverse transcriptase (RNA-dependent DNA polymerase) (PF00078; HMM-score: 173.5)
    and 3 more
    Intron-mat_II (CL0359) GIIM; Group II intron, maturase-specific domain (PF08388; HMM-score: 63.3)
    RdRP (CL0027) RdRP_1; Viral RNA-dependent RNA polymerase (PF00680; HMM-score: 18.6)
    Saposin_like (CL0707) SapB_1; Saposin-like type B, region 1 (PF05184; HMM-score: 14.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9043
    • Cytoplasmic Membrane Score: 0.0423
    • Cell wall & surface Score: 0.0228
    • Extracellular Score: 0.0306
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003704
    • TAT(Tat/SPI): 0.001133
    • LIPO(Sec/SPII): 0.00061
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS36736 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQNWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVISPICEPHFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNIIEDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLRFVRYADDCVITVGSEAAAKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFWKSSDGWKSRPHQDSVWRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMKSIVTSIDERLHTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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