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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 12-MAY-2020
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae 6A-10
- locus tag: HKM25_2031 [new locus tag: HKM25_RS09910 ]
- pan locus tag?: PNEUPAN003574000
- symbol: purR
- pan gene symbol?: purR
- synonym:
- product: pur operon repressor PurR
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: HKM25_2031 [new locus tag: HKM25_RS09910 ]
- symbol: purR
- product: pur operon repressor PurR
- replicon: chromosome
- strand: -
- coordinates: 1940313..1941116
- length: 804
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP053210 (1940313..1941116) NCBI
- BioCyc:
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_1776 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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781ATGGTTGTCATTTCCAACTATTTGATTAATAATCCTTATAAACTAACTAGTCTCAATACT
TTTGCTGAAAAGTATGAGTCTGCTAAATCATCCATCTCAGAAGATATCGTCATTATCAAA
CGCGCCTTTGAGGAAATTGAAATCGGTCATATCCAGACAGTGACTGGGGCTGGCGGAGGT
GTCATCTTCACACCGTCTATTTCGAGTCAGGATGCTAAGGAAATGGTTGAAGACTTGCGT
ACCAAGTTGTCAGAAAGTGACCGTATCTTGCCAGGTGGTTATATCTATCTGTCTGATTTG
CTTAGCACACCAGCCATCTTGAAAAATATTGGTCGTATTATTGCCAAAAGCTTTATGGAC
CAAAAAATTGACGCGGTTATGACCGTAGCAACTAAGGGTGTGCCACTTGCAAATGCAGTT
GCCAATGTCCTCAATGTCTCTTTTGTCATTGTGCGCCGTGACCTGAAAATTACCGAAGGT
TCAACTGTTAGCGTCAACTATGTTTCAGGTTCAAGTGGTGACCGTATCGAGAAAATGTTC
CTTTCAAAACGTAGTCTTAAGGCAGGCAGCCGTGTCTTGATTGTGGATGACTTCTTGAAA
GGTGGCGGAACGGTCAACGGTATGATTAGTCTCTTGCGCGAGTTCGACTCAGAACTGGCA
GGTGTAGCGGTCTTTGCGGACAATGCCCAAGAAGAACGTGAAAAGCAGTTTGACTACAAG
TCACTCTTGAAGGTAACTAATATTGATGTCAAGAACCAAGCCATCGATGTTGAGGTTGGC
AATATCTTTGACGAAGATAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: HKM25_2031 [new locus tag: HKM25_RS09910 ]
- symbol: PurR
- description: pur operon repressor PurR
- length: 267
- theoretical pI: 4.91452
- theoretical MW: 29183.2
- GRAVY: 0.0116105
⊟Function[edit | edit source]
- TIGRFAM: Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis pur operon repressor PurR (TIGR01743; HMM-score: 440.1)Regulatory functions DNA interactions pur operon repressor PurR (TIGR01743; HMM-score: 440.1)and 5 morePurines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 62)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides xanthine phosphoribosyltransferase (TIGR01744; EC 2.4.2.22; HMM-score: 54.1)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 44.2)Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 32.1)Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 16.3)
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM: PRTase-like (CL0533) Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 103.4)HTH (CL0123) PuR_N; Bacterial purine repressor, N-terminal (PF09182; HMM-score: 86.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
- genes regulated by PurR, TF important in Purine metabolism: in TIGR4
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.015705
- TAT(Tat/SPI): 0.000333
- LIPO(Sec/SPII): 0.000707
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: QJS37711 NCBI
- UniProt:
⊟Protein sequence[edit | edit source]
- MVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDIVIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGYIYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVRRDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMISLLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1776 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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