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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_2258 [new locus tag: HKM25_RS10995 ]
  • pan locus tag?: PNEUPAN002575000
  • symbol: HKM25_2258
  • pan gene symbol?: sorC_3
  • synonym:
  • product: PTS system sorbose-specific iic component family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_2258 [new locus tag: HKM25_RS10995 ]
  • symbol: HKM25_2258
  • product: PTS system sorbose-specific iic component family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2141696..2142364
  • length: 669
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (2141696..2142364) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1990 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGGTTGGCTTAGTCTTAGGAGATTTCACCCAAGGTGTTCTTATTGGTTCAGCTCTTGAA
    TTAACTTGGCTCGGTGTAACAGGTATTGGAGGTTACACTCCACCAGATACTATTTCAGGT
    GCGATTATTGGTACTGCATTTGGTATTTTATCTGGTCAAGGAGAAACTGCTGGTATCGCT
    ATAGCAGTTCCAATTGCAGTTGCTACCCAACAGTTGGATGTTCTTGCAAAAACTTTAGAT
    GTTTATTTTGTGAAAAAAGCTGATAATGATGCTAAAAACGGAGATTATTCAAAGATCGGT
    TTTTATCATTATTCAAGTTTGGTTTTAATCACGTTATTTAAAATTGTACCAATTTTCCTA
    GCTATTATGCTTGGAGGGGAATATGTGGCAGACTTGTTTGCTAAGGTTCCACCAATCGTT
    ATGCAGGGACTTAACTCTGCAGGTGCTTTACTACCTTCAATTGGTTTTGGTATGCTTTTA
    AATATGATGCTCAAGAAAAATATGTGGGTATTCTTGTTGATTGGATTCATTTGTTCTGTG
    TATGGAGGAATGTCAACCATTGGGATCTCACTAGTTGGTATTGCGGTAGCATACTTCTAC
    GATATGATTGGAAGTAAACCACAAGAAACAACTTCAAGTAGTGATGTTGAGGAGGATCTT
    GATCTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    669

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_2258 [new locus tag: HKM25_RS10995 ]
  • symbol: HKM25_2258
  • description: PTS system sorbose-specific iic component family protein
  • length: 222
  • theoretical pI: 4.18578
  • theoretical MW: 23378.3
  • GRAVY: 0.729279

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, mannose/fructose/sorbose family, IIC component (TIGR00822; HMM-score: 157.7)
    Signal transduction Signal transduction PTS PTS system, mannose/fructose/sorbose family, IIC component (TIGR00822; HMM-score: 157.7)
    and 2 more
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 15)
    Genetic information processing Protein fate Protein folding and stabilization peptidase Do (TIGR02037; EC 3.4.21.-; HMM-score: 15)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined EII-Sor; PTS system sorbose-specific iic component (PF03609; HMM-score: 209.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.047477
    • TAT(Tat/SPI): 0.006778
    • LIPO(Sec/SPII): 0.017293
  • predicted transmembrane helices (TMHMM): 4

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS37906 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVGLVLGDFTQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAVATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLGGEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGGMSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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