From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_533 [new locus tag: HKM25_RS12135 ]
  • pan locus tag?: PNEUPAN001421000
  • symbol: HKM25_533
  • pan gene symbol?: —
  • synonym:
  • product: thioredoxin domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_533 [new locus tag: HKM25_RS12135 ]
  • symbol: HKM25_533
  • product: thioredoxin domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 502947..503432
  • length: 486
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (502947..503432) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAGAAACAAAAGATAAAATCGCTATTACTTGTACCACTTGTATTTGCATCTATTACT
    ACATGTGTTGTATATGCAGAAGAACAGACTACTTCTTCCTCTATCCAGGCTAATGATAGT
    TCTGTTGTGGCACCAGATTTGCCATCGGCTAAGGAAAAGGTGGAGCATAAACCTTCTGTT
    GTAACCCCAGAAGAGTATGAGAAGAATGTTACGGACTTTAAAAAGATAGATATTGAAACT
    GTACGTCAATCTTTTACAGAGGATCAATTGGAACATACTATTTATTTTGGTAGAAAAACT
    TGCTCTCATTGTCGTCAATTTTCTCCTGAATTGAAAGAATTTAATAACTTGATTGAAAAG
    AAGTTAGAGTATTATGATTTGGATGGTAAGGATTTTGATGGGGAAGCGAGAGAGTTTCTA
    TTTAAAAAATGGACATCCGATATCTGGATGGGTTGGTGGCGGAGCAACTGCACAACAGGT
    GTATGA
    60
    120
    180
    240
    300
    360
    420
    480
    486

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_533 [new locus tag: HKM25_RS12135 ]
  • symbol: HKM25_533
  • description: thioredoxin domain-containing protein
  • length: 161
  • theoretical pI: 5.35325
  • theoretical MW: 18673
  • GRAVY: -0.570807

⊟Function[edit | edit source]

  • TIGRFAM:
    putative bacteriocin transport accessory protein (TIGR01295; HMM-score: 33)
    type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB (TIGR02738; HMM-score: 32.5)
    and 3 more
    glutaredoxin (TIGR02180; HMM-score: 16)
    Metabolism Energy metabolism Electron transport thioredoxin (TIGR01068; HMM-score: 14.8)
    Genetic information processing Protein fate Protein folding and stabilization periplasmic protein thiol:disulfide oxidoreductases, DsbE subfamily (TIGR00385; HMM-score: 13.1)
  • TheSEED:
  • PFAM:
    Thioredoxin (CL0172) Thioredoxin; Thioredoxin (PF00085; HMM-score: 18.5)
    Thioredoxin_8; Thioredoxin-like (PF13905; HMM-score: 17.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.008
    • Cell wall & surface Score: 0.0251
    • Extracellular Score: 0.9669
  • SignalP: Signal peptide SP(Sec/SPI) length 26 aa
    • SP(Sec/SPI): 0.740801
    • TAT(Tat/SPI): 0.000296
    • LIPO(Sec/SPII): 0.257873
    • Cleavage Site: CS pos: 26-27. VYA-EE. Pr: 0.6588
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS36245 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKQKIKSLLLVPLVFASITTCVVYAEEQTTSSSIQANDSSVVAPDLPSAKEKVEHKPSVVTPEEYEKNVTDFKKIDIETVRQSFTEDQLEHTIYFGRKTCSHCRQFSPELKEFNNLIEKKLEYYDLDGKDFDGEAREFLFKKWTSDIWMGWWRSNCTTGV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=HKM25_533&oldid=25199"