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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-MAY-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_573 [new locus tag: HKM25_RS02805 ]
  • pan locus tag?: PNEUPAN001479000
  • symbol: HKM25_573
  • pan gene symbol?: —
  • synonym:
  • product: helix-turn-helix domain protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_573 [new locus tag: HKM25_RS02805 ]
  • symbol: HKM25_573
  • product: helix-turn-helix domain protein
  • replicon: chromosome
  • strand: +
  • coordinates: 540675..541124
  • length: 450
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP053210 (540675..541124) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0508 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGCAAGACAATTATACTACAAAAGGCAAACATTTGACAATCGATAGCCGTCGCTTAATC
    GAACGATGGAAAAAAGAAGGAAAATCAAATAGAGAAATTGCCTCTCTACTTGGAAAAGCT
    CCTCAAACTATCCATACTGAAATCAAGTATGGGACAGTCCGACAATGTCTTGGAAAAGGG
    CGCTTCAAAGAGATTTATTCTGCCGACTACGCTCAACAGTCTTATGAAAATAATCGCAAG
    CACTCGGTCAAGAAATCAAGCTTGACTAAGAAACTAAAGGAAAAGATTCTCCACTATCAT
    AACCAAAAATTTTCGCCTGAAATGATGGTGATGGCTAAAGGGGTTAACGTGGGAATTTCA
    ACCATTTACTATTGGATTCATCGTGGAAAATTGGGGTTAAGCAAGCAGGATCTGCTTTAT
    CCTAGAAAAGGAAAAGCGCTTAAGAAATAG
    60
    120
    180
    240
    300
    360
    420
    450

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_573 [new locus tag: HKM25_RS02805 ]
  • symbol: HKM25_573
  • description: helix-turn-helix domain protein
  • length: 149
  • theoretical pI: 10.7611
  • theoretical MW: 17371.1
  • GRAVY: -0.912752

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General DNA binding domain, excisionase family (TIGR01764; HMM-score: 16.6)
    RNA polymerase sigma-70 factor, Bacteroides expansion family 1 (TIGR02985; HMM-score: 16.3)
    transcriptional regulator EpsA (TIGR03020; HMM-score: 14.9)
    RNA polymerase sigma factor, sigma-70 family (TIGR02937; HMM-score: 14.5)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    HTH (CL0123) HTH_38; Helix-turn-helix domain (PF13936; HMM-score: 64.4)
    and 7 more
    HTH_23; Homeodomain-like domain (PF13384; HMM-score: 21.3)
    HTH_17; Helix-turn-helix domain (PF12728; HMM-score: 20.9)
    Sigma70_r4_2; Sigma-70, region 4 (PF08281; HMM-score: 20.4)
    HTH_28; Helix-turn-helix domain (PF13518; HMM-score: 17.4)
    PKinase (CL0016) PK_Tyr_Ser-Thr; Protein tyrosine and serine/threonine kinase (PF07714; HMM-score: 15.5)
    HTH (CL0123) GerE; Bacterial regulatory proteins, luxR family (PF00196; HMM-score: 14.8)
    HTH_29; Winged helix-turn helix (PF13551; HMM-score: 14.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9392
    • Cytoplasmic Membrane Score: 0.0019
    • Cell wall & surface Score: 0.0041
    • Extracellular Score: 0.0548
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009381
    • TAT(Tat/SPI): 0.002712
    • LIPO(Sec/SPII): 0.001734
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QJS36285 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTIHTEIKYGTVRQCLGKGRFKEIYSADYAQQSYENNRKHSVKKSSLTKKLKEKILHYHNQKFSPEMMVMAKGVNVGISTIYYWIHRGKLGLSKQDLLYPRKGKALKK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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