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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS04425 [old locus tag: HKM25_905 ]
  • pan locus tag?: PNEUPAN001943000
  • symbol: rsmI
  • pan gene symbol?: rsmI
  • synonym:
  • product: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS04425 [old locus tag: HKM25_905 ]
  • symbol: rsmI
  • product: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 874991..875860
  • length: 870
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (874991..875860) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0828 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCAGATTCAAAAAAGTTTTAAGGGGCAGTCTCCCTATGGCAAGCTGTATCTAGTGGCA
    ACGCCGATTGGCAATCTAGATGATATGACCTTTCGAGCTATCCAGACCTTGAAAGAAGTA
    GATTGGATTGCTGCTGAGGATACGCGCAATACAGGTCTTTTGCTCAAGCATTTTGACATT
    TCCACCAAGCAGATCAGTTTTCATGAGCACAATGCCAAGGAAAAAATTCCTGATTTGATT
    GGTTTCTTGAAAGCAGGGCAAAGTATTGCTCAGGTCTCTGATGCCGGTTTGCCTAGCATT
    TCAGACCCTGGTCATGATTTAGTTAAGGCAGCTATTGAGGAAGAAATTGCAGTTGTGACA
    GTTCCAGGTGCCTCTGCAGGAATTTCTGCCTTGATTGCCAGTGGTTTAGCGCCACAGCCA
    CATATCTTTTACGGTTTTTTACCGAGAAAATCAGGTCAGCAGAAGCAATTTTTTGGCTTG
    AAAAAAGATTATCCTGAAACACAGATTTTTTATGAATCACCTCATCGTGTAGCAGACACG
    TTGGAAAATATGTTAGAAGTCTACGGTGACCGCTCCGTTGTCTTGGTCAGGGAATTGACC
    AAAATCTATGAAGAATACCAACGAGGTACTATCTCTGAGTTATTAGAAAGCATTGCTGAA
    ACGCCACTCAAGGGCGAATGTCTTCTCATTGTTGAGGGTGCCAGTCAGGGTGTGGAGGAA
    AAGGACGAGGAAGACTTGTTCGTAGAAATTCAAACCCGCATCCAGCAAGGTGTGAAGAAA
    AACCAAGCTATCAAGGAAGTCGCTAAGATTTACCAGTGGAATAAAAGTCAGCTCTACGCT
    GCCTACCACGACTGGGAAGAAAAACAATAA
    60
    120
    180
    240
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    540
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    780
    840
    870

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS04425 [old locus tag: HKM25_905 ]
  • symbol: RsmI
  • description: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase
  • length: 289
  • theoretical pI: 4.99406
  • theoretical MW: 32398.5
  • GRAVY: -0.341522

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.1.198?  ExPASy
    16S rRNA (cytidine1402-2'-O)-methyltransferase S-adenosyl-L-methionine + cytidine1402 in 16S rRNA = S-adenosyl-L-homocysteine + 2'-O-methylcytidine1402 in 16S rRNA
  • TIGRFAM:
    Genetic information processing Protein synthesis tRNA and rRNA base modification 16S rRNA (cytidine(1402)-2'-O)-methyltransferase (TIGR00096; EC 2.1.1.198; HMM-score: 273.4)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin precorrin-4 C11-methyltransferase (TIGR01465; EC 2.1.1.133; HMM-score: 20.7)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin uroporphyrinogen-III C-methyltransferase (TIGR01469; EC 2.1.1.107; HMM-score: 20.7)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined TP_methylase; Tetrapyrrole (Corrin/Porphyrin) Methylases (PF00590; HMM-score: 80.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002945
    • TAT(Tat/SPI): 0.000138
    • LIPO(Sec/SPII): 0.000368
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001166880 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIAAEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISDPGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFGLKKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESIAETPLKGECLLIVEGASQGVEEKDEEDLFVEIQTRIQQGVKKNQAIKEVAKIYQWNKSQLYAAYHDWEEKQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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