From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS06340 [old locus tag: HKM25_1301 ]
  • pan locus tag?: PNEUPAN002642000
  • symbol: HKM25_RS06340
  • pan gene symbol?: pglJ
  • synonym:
  • product: glycosyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS06340 [old locus tag: HKM25_1301 ]
  • symbol: HKM25_RS06340
  • product: glycosyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1267443..1268546
  • length: 1104
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1267443..1268546) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1200 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGTGGCTAAGAAAAAAATCTTATTTTTTATGTGGTCTTTTTCTCTTGGAGGTGGTGCA
    GAGAAGATTCTATCAACCATTGTTTCAAATCTGGATCCAGAAAAGTATGATATTGATATT
    CTTGAAATGGAGCACTTTGACAAGGGATATGAATCTGTTCCAAAGCATGTACGCATTTTA
    AAATCCCTTCAAGATTATCGCCAAACCAGATGGTTACGAGCTTTTTTGTGGAGAATGAGA
    ATTTATTTTCCAAGACTGACTCGTCGTTTGCTTGTAAAAGATGATTATGATGTTGAAGTT
    TCTTTTACCATTATGAATCCACCACTGTTGTTCTCTAAAAGAAGAGAAGTCAAGAAGATA
    TCTTGGATTCATGGAAGTATTGAAGAACTTCTTAAGGATAGCTCTAAAAGAGAATCACAT
    AGAAGCCAGTTGGATGCTGCGAATACAATTGTAGGGATTTCAAAAAAGACCAGCAATTCT
    ATCAAGGAAGTTTATCCAGATTATGCTTCTAAATTACAGACAATCTACAATGGATATGAT
    TTTCAGACTATTCTAGAAAAATCTCAAGAGAAGATCGATATCGAGATTGCTCCTCAAAGT
    ATCTGTACTATCGGACGGATTGAGGAAAATAAGGGTTCTGACCGTGTAGTGGAAGTGATA
    CGATTATTACACCAAGAGGGAAAAAACTATCATCTCTATTTTATCGGGGCTGGTGATATG
    GAAGAGGAACTGAAAAAACGAGTCAAAGAGTATGAGATTGAGGACTATGTACATTTCCTT
    GGTTATCAAAAAAATCCTTATCAGTATTTATCTCAGACGAAAGTTCTCTTGTCTATGTCT
    AAACAAGAAGGCTTTCCTGGAGTGTATGTGGAGGCCTTGAGTCTGGGACTCCCTTTTATC
    TCTACGGACGTTGGAGGGGCTGAGGAATTATCCCAAGAAGGACGATTTGGACAAATCATT
    GAGAGCAATCAAGAGGCAGCTCAGGCGATTACTAATTACATGACTTCTGCCTCAAACTTT
    AATGTCGATGAGGCTAGCCAATTCATTCAACAATTTACAATTACAAAACAAATCGAACAA
    GTAGAAAAACTATTAGAGGAGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1104

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS06340 [old locus tag: HKM25_1301 ]
  • symbol: HKM25_RS06340
  • description: glycosyltransferase
  • length: 367
  • theoretical pI: 5.9777
  • theoretical MW: 42582.3
  • GRAVY: -0.43951

⊟Function[edit | edit source]

  • reaction:
    EC 2.4.-.-?  ExPASy
  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Glutathione and analogs N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA (TIGR03999; EC 2.4.1.-; HMM-score: 76.3)
    sugar transferase, PEP-CTERM/EpsH1 system associated (TIGR03088; HMM-score: 74.6)
    glycosyltransferase, GG-Bacteroidales peptide system (TIGR04157; EC 2.4.1.-; HMM-score: 62.6)
    and 12 more
    colanic acid biosynthesis glycosyltransferase WcaL (TIGR04005; EC 2.4.-.-; HMM-score: 50.6)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen synthase, Corynebacterium family (TIGR02149; HMM-score: 50.4)
    Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosylation protein GtfA (TIGR02918; EC 2.4.1.-; HMM-score: 41.9)
    PEP-CTERM/exosortase A-associated glycosyltransferase, Daro_2409 family (TIGR04063; EC 2.4.-.-; HMM-score: 37.6)
    putative glycosyltransferase, TIGR04348 family (TIGR04348; EC 2.4.1.-; HMM-score: 35.6)
    Unknown function Enzymes of unknown specificity glycosyltransferase, MSMEG_0565 family (TIGR04047; HMM-score: 30)
    D-inositol-3-phosphate glycosyltransferase (TIGR03449; EC 2.4.1.250; HMM-score: 29.7)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glycogen/starch synthase, ADP-glucose type (TIGR02095; EC 2.4.1.21; HMM-score: 26.4)
    sucrose-phosphate synthase, putative, glycosyltransferase domain (TIGR02472; EC 2.4.1.14; HMM-score: 18.4)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides sucrose synthase (TIGR02470; EC 2.4.1.13; HMM-score: 18.2)
    colanic acid biosynthesis glycosyltransferase WcaC (TIGR04015; EC 2.4.-.-; HMM-score: 16)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Biotin biotin synthase (TIGR00433; EC 2.8.1.6; HMM-score: 11.3)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    GT-B (CL0113) Glycos_transf_1; Glycosyl transferases group 1 (PF00534; HMM-score: 97.2)
    Glyco_trans_1_4; Glycosyl transferases group 1 (PF13692; HMM-score: 82.3)
    and 3 more
    Glyco_transf_4; Glycosyltransferase Family 4 (PF13439; HMM-score: 27.9)
    Glyco_trans_1_2; Glycosyl transferases group 1 (PF13524; HMM-score: 17.6)
    no clan defined DUF3819; CCR4-Not complex, Not1 subunit, domain of unknown function DUF3819 (PF12842; HMM-score: 13.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.0727
    • Cytoplasmic Membrane Score: 0.8954
    • Cell wall & surface Score: 0.0013
    • Extracellular Score: 0.0307
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.188137
    • TAT(Tat/SPI): 0.001564
    • LIPO(Sec/SPII): 0.14094
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000225903 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEMEHFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSFTIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNSIKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVEVIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVLLSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYMTSASNFNVDEASQFIQQFTITKQIEQVEKLLEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=HKM25_RS06340&oldid=23660"