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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS07595 [old locus tag: HKM25_1556 ]
  • pan locus tag?: PNEUPAN002912000
  • symbol: HKM25_RS07595
  • pan gene symbol?: —
  • synonym:
  • product: tail fiber domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS07595 [old locus tag: HKM25_1556 ]
  • symbol: HKM25_RS07595
  • product: tail fiber domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1499074..1505058
  • length: 5985
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1499074..1505058) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    4321
    4381
    4441
    4501
    4561
    4621
    4681
    4741
    4801
    4861
    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    5401
    5461
    5521
    5581
    5641
    5701
    5761
    5821
    5881
    5941
    TTGAAAGAAACTAAGCGCAAGGCTGAGGAAGCTTTGCGAAATGCTGGCGCAAGTACCCTG
    CTTGCACAGGAAGCTAAGCGGATTGGGCTGGATTCTGTCGCTAGACTTGAAGCGTTTAAG
    TCGCAGACTACGAGCGCACAAACGGCTCTGTCGGGTGACTTGGACGCTCTGAAACGGACT
    ATCGCGAATGATATTCGACCGAAGCAAGCACAGGCTGAAGCTGAGATTGCCAAGCAAGTT
    GAAGCACTTAGCCGGACTAAGAATGAACTGGCTGGCGCAAGTAACCTACTTGCACAGGAA
    GCTAAGCGGATTGAGCTGGATTCTGTTGCTAGACTTGAAGCGTTTAAGTCGCAGACTACG
    AGCGCACAAACGGCTCTGTCGGGTGACTTGGACGCTCTGAAACGGACTATCGCGAATGAT
    ATTCGACCGAAGCAAGCACAGGCTGAAACTGAGATTGCCAAGCAAGCTGAAGCACTTAGC
    CGGACTAAAAATGAACTGTCTGGCGTGAAGTCAGCGCAAGCGACGTATGAGGAGACGACG
    ACTCGTAGACTGTCAGAACTGACCAACTTGGCCAATGGTAAAGCCAGCAAGTCAGAACTC
    ACGCAAACAGCTGAGGAGCTGGCTAGTCGGATTGCGAGTGTGCAGGCAGGTAGTTCACGG
    AATTACTTCAGGAATTCACGTTCAAGAACGTTCACAACAGGAGGTCAAGCGGTATACGAC
    TATCGAACATTCATAGTTCCTGATTTCTGGAAGAACAGTGACAGGTTCAAGCGTGATTAT
    GTTCGCATATCTTTTGATGTGACTTTCCCTGTCGCCCTAGTAAATGACATGCCTGCTATG
    GTGCATTTTAGTGCTCATCCATGGTATGCCTACAGAAACTTAATTTTTAAAGGTGGAACT
    GTCGAACGCCAACATTTTGAGTTTACGATTGACTTGTCTAGTTCTTCTGAGGACTATCAG
    ACTAATAATGTGTTCATTCGTTTTGGTACTAATTATGGATTTCCTGCTGGTCTGCAGGTC
    GTCATTGAGAACGCTATGTTATCGGTTGGTAATTATTTTCCAGCCTATCAACCAGCGTAT
    GAAGACCAAGAAGACCGTGTCTCAGCAGTAGAATCGACCTTCAAACAACGAGCCAACTCG
    CTCGAAGCTGGTGTGAATCGTCTGACTGAAGGCCTTAGAACTAAAGCCGATATCAGCTCA
    CTCAATGTGACTGCTGAAAATATCCGGCAATCTGTGAAGAGCCTTGAGACAGATACGCAG
    AACAAGCTAAATCAGAAGTTGAGTCAGGCTGAATTTGAGGTGCGAGCCGGCTCTATCCGT
    CAGGAAATCCTGAACGCAACCAAGGATAAAGCCAACAAGTCAGAACTCACGCAGACAGCT
    GAGGAGCTAGCTAGTAAGATAGCGAGTGTGCAGGCATCCGGTCGAAATCTATTCTTGAAC
    TCACTATTCAAGCAGGATATTTCAAAAACAGGAATTTGGACAACGAGTACATATACGGCT
    ACTATCGATAGCGAAAGTAAGTATCTTGGACACAAGGCTCTTAAAATTATAGGTCTGAAT
    CCATCTGGCCGTGATGGAGGGAATCCCAAGGTTACTTATCCAGCTCTGGGTCAATTCGGG
    AAAGTAATTCCCGGAAGTACGACTAATCAAGATGTAACCATTAGTTTTTATGCTAAGGCA
    AATAAAAATGGAATAATGCTAAGATCTCGATTAGGGAATATCGGATATAAAACTGGAAAT
    GTGACATTGTCGACAGAAATTAAACGATATGTTGTCCATATTCCAAAAGGTTGGACAAAC
    GAATCCAAGCAGACCACAAATGAATGGTTGTTCAATTTCAACCAGGAAGGAACCGTTTGG
    ATTTGGATGCCGAAGTTTGAAATAAGCGATGTAGATACTTCTTATTCAGAAGCTCCTGAA
    GATATAGAAGGTCAGATTTCAGCAGTAGAATCGACCTTCAAACAACGAGCCAACTCGCTC
    GAAGCTGGTGTGAATCGTCTGACTGAAGGCCTTAGAACTAAAGCCGATATCAGTTCACTC
    AATGTGACTGCTGAAAATATCCGGCAATCTGTGAAGAGCCTTGAGACAGACACGCAGAAC
    AAGCTAAATCAGAAGTTGAGTCAGGCTGAATTTGAGGTGCGAGCTGGCTCTATCCGTCAA
    GAAATCCTGAACGCAACCAAGGATAAAGCCAACAAGTCAGAACTCACGCAGACAGCTGAG
    GAGCTCTCTAGTAAGATAGCGAGTGTGCAGGTCGGAGGAATCAACCTCTTGCGTAATACT
    GCGAGTTTGTTGATTGGCGATCGTTCAAAAGGATGTTGGATGAGTGCAAGCGGAGGAAAT
    GGGCGAGCGATTAGCGTAGAAGTTTTGGATTCTCCCAAAAAAATGATAAAAAACATGATT
    CGTGTTATTGAAAATACGAATGGTGGAAATAAAGATTTAACTCAACTTGTTAGATTGCGA
    ATTGGTGAAAAGTACACGATTTCTTGTTATGCAAGGATTGCTAGCGATAGCCCAAATGCA
    AACGTGAACTTGCTATTTCGTTCGTGGGCAAATAATACCGATTTAAATCGCAAATTTCAG
    AAATCCATCTCTCATAAAAATTGGCAAAAATATTCATTTACATTTACTGCTGATGCAATT
    GAAAATTCAATTCAATTTGGACAATCTGGCGCAGGAATTATCGAAATATGCGCTCCGAAA
    ATCGAATCAGGAACGTTAGCGACTGATTACAGCGAAGCTCCTGAAGATATAGAAGGTCAG
    ATTTCAACAGTTGAATCGACCTTCAAACAACGAGCCAACTCACTCGACGCTGGTGTAAGA
    AGCTTGACTGAAGGGCTTAGAACCAAAGTGGATATCAGTTCACTCAATGTGACTGCTGAA
    AATATCCGGCAATCTGTGAAGAGCCTTGAGACAGACACGCAGAACAAGCTAAATCAGAAG
    TTGAGTCAGGCTGAATTTGAGGTGCGAGCCGGCTCTATCCGTCAGGAAATCCTGAACGCA
    ACCAAGGATAAAGCAGATAAGACTTTAGTTGTATCTGAAGCTGGGAAATTGCGTGAAGAA
    TTTTCAAAAATGAAGGTGGGAGACCGGAATCTATGGATAAAATCCAAGACGGTTGGAGCT
    GTAATTGAAAAATTACCTGAAAACCACGTCACAGGTCAAAAAGAATGCTATAGGCTAGAG
    AACAACTCTACTTTAACGTTCAACCTTGAACCAGATTTCAGCTCAAGGTTGTACCAAAAA
    GTTACTTTTAGCGCTTGGATCAAGTACGAAAATGTAGTCCAAGGTCGAAATTTTTGGAAT
    GTATTTAATTGCTTCAAACATTATCTTTTTAGAAAAAATAGTGAGACCGGAGTACAGAGT
    GGTCCAGATTATGCTACGCTTGGTATGTATAAAGGTTCGGCAGATTGGAAATATATTACA
    TTCACTTATGACTACTCTGAAAAAACAAATTTTGATCAATTGAAGACATCATTGCGATTC
    AATCTTGAAGGTGCTACAAGCGGTACAGCTTGGGTAACAGGACTCAAGGTTGAAATCGGT
    AGTGTGGCGACGGACTGGAGTCCTGCGCCTGAGGACGCTGATGGTCTCATTACTGAAGCT
    AAGGCTACCTTTGAGCGGACAGCTCAGGGCTTGCGAACCGACTTATCAGCTATTCAGGAA
    TATGTAAATAAAGACGGTCAGCGACAGGAAGCCCTACAGCGCTATACTCGTGAGGAGAGC
    GCGAGACAAGCGACAGCAGTCCGTGAGCTGGTCAATCGTGATTTCGTTGGTAAGGCTACT
    TATCAAGAAGATGTTAAGGGTATCAATCAGAGGATTGAAGCTGTTAAAACTAGTGCGAAT
    AAAGACATCGCTAGTCAAATCGCTAGCTATCGCCAATCTGTAGATGGTAAGTTCACGGAT
    ATTTCAAGTCAGATAACTACTTATAAGCAAGATGTGGGCGGTCAAATCAGTGGTCTATCA
    AATAGACTTACAAGCAGTGAGCAAGGAACCACTACTCAGATTTCAAATCTTTCAAATCGG
    ATAAACAGTAATAAGCAAGGCACAGATAATCAGATTTCAAATTTAAAGACTCAGGTCGCT
    ACAAACAAGGATAATGCTGAACGACAAATGGGTAGAATATCTGATCAGGTTTCTGCAAAC
    AAAGCGAATGCTGATAGTCAATTTGCGAATGTGACCAATCAACTAGCTCGAAAAGTAGAG
    ACTACTGACTTCCAGCGTGTTAAGGAAACCAGTAAACTTTACGAGCGGATTTTGGGCAAT
    ACTGAAAATGGAATTGCGGATAAGGTTGCTCGCATGGCTCTGACCAATCAACTATTTCAG
    GTTGAGGTTGGGAAATATAGTGTAAGCGGCCCTAACCTCATTAAGAATAGTGATTTTAAA
    AATGCTACGAATGAATGGGGCTCAACTCAAAATTTAGGAAGATTGGTTAAGCATAGCTTT
    TATCACAACGGGCAGAAAGACCTTATGCGTTTAAGTAATGCAACTAAAAACGAAAACTTT
    TTGTATAGTCACCGTTTTAATCTTGAACGAAATACTGACTATGTACTGAATTTTAGAGGA
    TTTAACAACAGTGCTCTAGCAAGCTATGATGTTTATATTTTGGGACGAAGAGCAGGCGAG
    AGCGATGGATTCACAATCGTTAAGAAAGTTGTTAGCAGCAAGAAACTATCTACCTCTAGA
    TGCGAAGATGTCTCAGTAACTTTTAATTCCGGAGAAATGGATAATGCTTACATTCGTTTT
    GATAACAATGGCTCATCATCAGGAACAGCTGATTTGTATATTACAGAAGTTGACTTGTAC
    AAAGGTTATAAACCTAGAACATGGCAACCACATCCAGAAGATGCAGTCGCAGATGCGAAT
    AAGAAGCTTGAAGCAACGCAAACAAAAATGACTCAACTAGCTGGCTCATGGGTAGTTGAA
    AACATCAACTCGGCTGGAGATATCATCTCTGGAATCAATCTTGGCGCCAATGGACATAAC
    CGCTTCGTTGGGAAATTGACCCACATCACTGGAGAGACCCTGATTGACAGAGCAGTCATC
    AAGTCTGCCATGGTTGATAAGCTCAAAACGGCTAATTTTGAAGCTGGTTCGGTCACGACT
    ACGATATTAGAAGCTGAAGCGGTAACTGCTGAGAAGTTGAAAGTTGACAATGCGCTTATT
    AAAAAATTAACTGCAAATGACGCTTTTATTGACCGACTGACATCTAAACGTATCTTCTCT
    ACTAAGGTTGAGTCCGTCATTTCTAGCTCAACCTTCCTAGAAGCCTATCAAGGCCGAATC
    GGTGGATTCACACTTGGTCAATTTGACCAGGGTGGCGGTCGCTGGATTTCAGGTGTTAAT
    CAGTTCTCTGTTGGTATGGGGAATGGTGCCGGGTATGGAGTCCGGACAGCCTTCTGGGCG
    AACTGGGGAAATAATTGGAACTATGCCGGACCTAAAGCATGGAACGTCAATACTGATGGG
    AAAATGTACTGTAGGAATGAAGTCGGTTTTTATGATCAAGTGGATTTTTCGAATTCATCG
    AGAGCAAACTTCTATGGGAATACTACTTTTTCTCGTTCTCCTGTGTTTTCAAATGGTATC
    GAACTTGGAAGTAAAGATGTGCTTGGTGATGGTTGGAATCCCAAAGGCGGAAGGAATGCG
    GTTGTTTGGTGGAATCAGGTCGGTAGCGGTAGCTTGAAGTATTGGATGGAACAAAAATCA
    GACAGACGCTTAAAAGAGAACATCACAGATACAGCTGTGAAAGCCTTGGACAAAATCAAC
    AGATTAAGAATGGTTGCATTTGATTTCATCGAAAATAAGAAACATGAGGAGATTGGTCTA
    ATAGCTCAAGAGGCTGAAACCATCGTTCCAAGAATTGTCTCACGAGATCCTGAGAATCCA
    GATGGCTATCTACATATCGACTATACCGCTTTAGTTCCTTACTTAATCAAGGCTATTCAA
    GAATTAAATCAAAAAATAGAAAAAATGGAGAAAACAATAGCATGA
    60
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    5820
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    5940
    5985

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS07595 [old locus tag: HKM25_1556 ]
  • symbol: HKM25_RS07595
  • description: tail fiber domain-containing protein
  • length: 1994
  • theoretical pI: 9.39051
  • theoretical MW: 221449
  • GRAVY: -0.560682

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan defined Peptidase_S74; Chaperone of endosialidase (PF13884; HMM-score: 48.1)
    and 6 more
    DUF1497; Protein of unknown function (DUF1497) (PF07384; HMM-score: 27.4)
    Baculo_PEP_C; Baculovirus polyhedron envelope protein, PEP, C terminus (PF04513; HMM-score: 19.3)
    GBD (CL0202) DUF642; Protein of unknown function (DUF642) (PF04862; HMM-score: 15.5)
    no clan defined RPA_interact_M; Replication protein A interacting middle (PF14767; HMM-score: 14.8)
    HTH (CL0123) PuR_N; Bacterial purine repressor, N-terminal (PF09182; HMM-score: 14.4)
    no clan defined E2_bind; E2 binding domain (PF08825; HMM-score: 11)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 5.69
    • Extracellular Score: 4.31
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0219
    • Cytoplasmic Membrane Score: 0.0065
    • Cell wall & surface Score: 0.0946
    • Extracellular Score: 0.877
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.022766
    • TAT(Tat/SPI): 0.031962
    • LIPO(Sec/SPII): 0.004259
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_425289235 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQVEALSRTKNELAGASNLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAETEIAKQAEALSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKASKSELTQTAEELASRIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDVTFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVFIRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSAVESTFKQRANSLEAGVNRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKANKSELTQTAEELASKIASVQASGRNLFLNSLFKQDISKTGIWTTSTYTATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISAVESTFKQRANSLEAGVNRLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKANKSELTQTAEELSSKIASVQVGGINLLRNTASLLIGDRSKGCWMSASGGNGRAISVEVLDSPKKMIKNMIRVIENTNGGNKDLTQLVRLRIGEKYTISCYARIASDSPNANVNLLFRSWANNTDLNRKFQKSISHKNWQKYSFTFTADAIENSIQFGQSGAGIIEICAPKIESGTLATDYSEAPEDIEGQISTVESTFKQRANSLDAGVRSLTEGLRTKVDISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLREEFSKMKVGDRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNLEPDFSSRLYQKVTFSAWIKYENVVQGRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKYITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGLKVEIGSVATDWSPAPEDADGLITEAKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESARQATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDISSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGTDNQISNLKTQVATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERILGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRLVKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYILGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTADLYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAGSWVVENINSAGDIISGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILEAEAVTAEKLKVDNALIKKLTANDAFIDRLTSKRIFSTKVESVISSSTFLEAYQGRIGGFTLGQFDQGGGRWISGVNQFSVGMGNGAGYGVRTAFWANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRANFYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWWNQVGSGSLKYWMEQKSDRRLKENITDTAVKALDKINRLRMVAFDFIENKKHEEIGLIAQEAETIVPRIVSRDPENPDGYLHIDYTALVPYLIKAIQELNQKIEKMEKTIA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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