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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-FEB-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS07610 [old locus tag: HKM25_1558 ]
  • pan locus tag?: PNEUPAN002900000
  • symbol: HKM25_RS07610
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS07610 [old locus tag: HKM25_1558 ]
  • symbol: HKM25_RS07610
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1506646..1510239
  • length: 3594
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1506646..1510239) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    ATGGCAACTCTTGATGAATTGAAAGTCATGATTGACGCTGAGATAGCGCCTTTCAGGAAA
    AAGATGAAAGAAGTCGAGAATCAGGTCAAAGGAACATCTGACCGAGTGAAAAATGCTACT
    GCCAAAGTTCGTGAACAGTCGAACTCAATCGGTAGTGCGTTTGGTAAGCTGGCTAAGTTC
    GCTGGTTTTGCAATCCTTGGTAAGAAATTACTTGATGTTGGGATGTATTCAACGCAGACA
    GCTCTTGAAGTGTCAGCGTCTATGAACCAAATCAAGCGACAGATGGGCGAGAGTTCGCAA
    TCTTTCTTGAAATGGGTTAACGATAACGCCAACGCTATGAATATGGGTGTGGGTGAGGCG
    ACCAACTACGGTGCAGTCTATTCAAACTTATTTTCTGGATTTATCAAAGATACCAACAAG
    CTAAGTGCTTATACTGCTAAGATGTTGCAGACATCGGCAGTGGTTGCTGAAGGTTCAGGG
    CGCACGATTACAGACGTTATGGAGCGGATTCGCTCAGGTTTGCTAGGGAACACCGAAGCA
    ATTGAGGACCTAGGAATCAACGTCAATGTGGCTATGATTGAGTCTACTGAAGCCTTTAAG
    AAGTTCGCAAACGGACAGAGCTGGCAACAGTTGGATTACCAAACCCAGCAACAAATCCGC
    CTTATGGCTATTCTGGAACAGGCTACAGCCAAGTATGGGAATACCTTGTCTAATTCTGTA
    AATGGTCGTATCAGCCTATTTAAGTCGCTGATGAAGGACGCAGCATTGAACCTTGGTAAC
    TCTATGTTACCGATTATCAATGCCATTATGCCTGTCTTGAACTCTTTTGCGATGGTCTTG
    AAGAACGTTACTGCTAAACTCGCTGAGTTTATCGCTTTGATGTTCAACAAGAAAGCAACA
    GTGAAAGATGGTGTTGGTGGAGCAGTTGGAGACATGGGTAACGCCATGAAAGACGCTGCA
    GGCGGAGCAGGAGACCTTGCTGATGCAGTAGACGACGCTGGAGATTCAGCAGGAGGACTT
    GCTGACAATCTTGGAGACTCCGCCAAAAACGCTAAGAAAGCTGCTAAAGAGTTGCTAGGT
    CTTTTGGGATTTGATGAGATTAACATCTTGCAAAAACCAAAAGATGACGACGCAGGCGGT
    TCTGGAGGCGGTGGCAAAGGTGGTAAAGGAAAGGGAGGCGGTGGCGGACCTTTCAAAGAC
    ATCTTGCCAGAAGTCGAGTTGACCGACATGGACAACAAATTCAAGAGCATTTTTGATGGT
    CTTGGAGATAAGCTCAAAGGGTTGTTTGACCTCTTCAAGAAAGGTTTTGATGCAGCATTT
    AGACCAGAAGGTATAAAACGCATTAAGACTGCCTTAGACCAAATAGCTAAGACAATGGGA
    GAAATCGTCACTGACCCAAGGGTTGTGAATGCCTTTAACCGAATGGCTGAGAAAATTGCT
    TATGCTTTAGGGCAAGTGACAGGCTCAATAACCACTATCGGGCTAGGTATCGGTGTTTTC
    CTTGCCGAAAGTATTGCAAATGGCCTTGGAAGGCAAAAAGAACGCATTATCAGGGCGCTA
    GTCGCTTTGTTTGATAATGTTGGTAACCTTTCCGAGGCAGTAGGAAACATAGCTCAGGAC
    TTTTCTAGTGCTTTCTACGACGTCATTACCTCAACTGGTGCGGTTCGTATCGGTAGCGCT
    ATTGTGTCAACTCTGTTGAGTTTGACATCTACCATTGTTGAAGTTGGTAGTAAATTAGCA
    GGAAGTTTGTTTAAAGGTTTTGAAAAAGTCGTTGTGACAAGCGCTCCTAAAATTTCATCA
    GTCTTCCAAAGTTTATTAGATACTGTTGCGCCTGTATTTGAGAGCATTGAAAGGTCTGTT
    AACAAATTTGGCGATGGCTTAAGTCGTGTTTATGATGAACATGTAGTCCCTGCTATTAAC
    TCTATTGCTAATGCTTTTAATGGGCTAATTGACATTATTCAGATTCTCTGGGAGAATTCC
    TGGCAACCTTTTGCTGAGTTTTTATCAGGAGTATTCGGTGTTAGTATTGAAGGAATTTCA
    GATTTATTAGGAGGTGGCCTTTTAGCCACTTTGGGACTATTGGCGGATGCTATTAAGTTA
    GTGGCAGATGGTTTCACCGTTTTTTCTGACTGGTGTAAAGAAAACAAAGAACCTATCGTA
    GCTTTGATAACAACTTGGCAAACGATTAATTTCTTATCATGGGCAGAACAAGCTGGAGGA
    CTTGCAGGAGCATTCAGCTTGTTAGGTAGTAAGGTCTCTTTGATTGTTGGAGGGATTAAG
    AATCTAGGTCTTGCTATTAAAGCATTGACATTTGATAAATTGGTCAGCTTCGGAGAAACC
    ATCTATTTGAATGCGTTGTATGCAAAAGATTTTGTTGTCAATTCAGGTAAAACAATTGCA
    CAGCTAGGGAAAACTGCTTTAGAACTTGGTAAATCATCTCTAGCATGGACTGCTCATACA
    GCGAAAATGGGATTAGCAACCGCGGCGGAATTTGCACATTCTGTTGCAGCAGGAGTCGCT
    ACAGCTGCAACATGGGCTTTTAATGCAGCGTTAGCAGTTTTGACAAGTCCAATAACCTTA
    GTTATTGCAGCAATCGCAGCCTTAATTGGTATCGGTGTCTTGCTCTACCAAAATTGGGAC
    ACTGTTGTTGAGTTTGCTAAAACTGCATGGCAAGGACTATGTGATTTTATCAGTGGTATT
    TGTCAAGCGATTGGCGAATTTTTCAGCGGTCTATGGACGAAACTCCAAGAAATCTTTGAG
    CCAATAGGTCAATGGTTTAGCGAGAAGTTCCAGCAAGCATGGGATGCTATTGGAAATATA
    TTTGGCAACTTAGGCTCTTGGTTTGGTGGCCGTTGGAATGATTCTAAAAACGCACTTGCC
    GAAGCAAATACTTGGCTTGGTGATAAGTTCAAGTCAGGTCGGGATAAAGTGAACTCAGCT
    TTTGAAAAAGTTGGCTCTTGGTTCGGTGACCGTTGGAATGATATCAAAGATGGAGTGAAA
    GAAGCTGATACATGGTTTGGAGAGAAATTTGAGAGTGCAAAAAAGAAAACTCAGAATCCT
    TTCCAAAAAATCGGTTCTTGGTTTGGCGATAGATGGAAAGATATGCAAGATGCCTTGAAA
    GAAATCCCCAACTGGTTCAAGAATCTGTTTAATGATGCAATGGATAATGCTAAAAACATC
    GTTAAAAGTGGTATCGATAAACTAAAAAGCTTCTTTAACTTTGATTGGAGCTTACCAAAA
    ATCAAACTCCCTCACTTTAATATATCTGGTAGCTTCAGCTTGATGCCTCCTAGAATTCCA
    TCATTCTCTGTAGATTGGTATGCACGAGGTGGTGTATTCAACTCTCCTAGCATCATTGGG
    GTCGGAGAAGCTGGTCAAGAAGCGGTAATGCCTCTTGAACGGAATACAGGATGGATTTCT
    ATCTTGGCTCAAAAACTGGCTGAAAGAATGCCTGCTAATAATGTACCTACAGGTTATTCA
    TTACCGGCTGGCGACATCGTTATCCAAATCGCAGGACATGAGTTCGGTCGGGTAGCAATC
    CAAGAAATTAACAAGGAACATGAACGAGCAGGTCAAACCTTGCTCAAGATTTAG
    60
    120
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    300
    360
    420
    480
    540
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    660
    720
    780
    840
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    960
    1020
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    1320
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    1560
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    1920
    1980
    2040
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    2160
    2220
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    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3594

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS07610 [old locus tag: HKM25_1558 ]
  • symbol: HKM25_RS07610
  • description: hypothetical protein
  • length: 1197
  • theoretical pI: 6.58018
  • theoretical MW: 128484
  • GRAVY: 0.0432749

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan defined Chlorosome_CsmC; Chlorosome envelope protein C (PF11098; HMM-score: 14.8)
    RETICULATA-like; Protein RETICULATA-related (PF11891; HMM-score: 13.6)
    Peptidase_PA (CL0124) Peptidase_S64; Peptidase family S64 (PF08192; HMM-score: 13.3)
    PDDEXK (CL0236) RmuC; RmuC family (PF02646; HMM-score: 12)
    T3SS-Chaperone (CL0419) YscO; Type III secretion protein YscO (PF07321; HMM-score: 12)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00779
    • TAT(Tat/SPI): 0.001076
    • LIPO(Sec/SPII): 0.00077
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000212181 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVREQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSFLKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLSAYTAKMLQTSAVVAEGSGRTITDVMERIRSGLLGNTEAIEDLGINVNVAMIESTEAFKKFANGQSWQQLDYQTQQQIRLMAILEQATAKYGNTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSFAMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAGDSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKGGGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIKRIKTALDQIAKTMGEIVTDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANGLGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLLSLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFGDGLSRVYDEHVVPAINSIANAFNGLIDIIQILWENSWQPFAEFLSGVFGVSIEGISDLLGGGLLATLGLLADAIKLVADGFTVFSDWCKENKEPIVALITTWQTINFLSWAEQAGGLAGAFSLLGSKVSLIVGGIKNLGLAIKALTFDKLVSFGETIYLNALYAKDFVVNSGKTIAQLGKTALELGKSSLAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNAALAVLTSPITLVIAAIAALIGIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEFFSGLWTKLQEIFEPIGQWFSEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTWLGDKFKSGRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQKIGSWFGDRWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKIKLPHFNISGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWISILAQKLAERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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