PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 24-APR-2025

⊟Summary

• organism: Streptococcus pneumoniae 6A-10
• locus tag: HKM25_RS07860 [old locus tag: HKM25_1605 ]
• pan locus tag^?: PNEUPAN002961000
• symbol: HKM25_RS07860
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: HKM25_RS07860 [old locus tag: HKM25_1605 ]
• symbol: HKM25_RS07860
• product: hypothetical protein
• replicon: chromosome
• strand: -
• coordinates: 1541093..1541287
• length: 195
• essential: unknown

⊟Accession numbers

• Location: NZ_CP053210 (1541093..1541287) NCBI
• BioCyc:
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  
  ATGAACCTACTATCAAGGATCAAAAACTATTTTTCAGAAGAGGTCAAAGAAACTAATCTC
  GACTGGAAAGAGGTCGCTTTAGACCTCAATCAATCACTAATTGAAACACAGGAAAAACTT
  CAAGAAGCGAATCAAGAAATTGCAGACTTGAAGAAAATCGTAGCAATCTACAAAGAAAAG
  GAGAAAGAAAAATGA
  60
  120
  180
  195
  

⊟Protein

⊟General

• locus tag: HKM25_RS07860 [old locus tag: HKM25_1605 ]
• symbol: HKM25_RS07860
• description: hypothetical protein
• length: 64
• theoretical pI: 4.64137
• theoretical MW: 7611.63
• GRAVY: -0.842188

⊟Function

• TIGRFAM:
• TheSEED:
• PFAM:
  no clan defined Nucleolin_bd; Nucleolin binding domain (PF16725; HMM-score: 19.4)
  ApoLp-III; Apolipophorin-III precursor (apoLp-III) (PF07464; HMM-score: 18.1)
  HMMR_N; Hyaluronan mediated motility receptor N-terminal (PF15905; HMM-score: 16.7)
  and 4 more
  DUF5365; Family of unknown function (DUF5365) (PF17326; HMM-score: 15.1)
  Syntaphilin; Golgi-localised syntaxin-1-binding clamp (PF15290; HMM-score: 14.9)
  Traffic (CL0147) Sec20; Sec20 (PF03908; HMM-score: 12.8)
  no clan defined B277; Domain of unknown function (PF17623; HMM-score: 12.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8705
  • Cytoplasmic Membrane Score: 0.0187
  • Cell wall & surface Score: 0.0135
  • Extracellular Score: 0.0973
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002355
  • TAT(Tat/SPI): 0.000131
  • LIPO(Sec/SPII): 0.000335
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: WP_001050924 NCBI
• UniProt:

⊟Protein sequence

• MNLLSRIKNYFSEEVKETNLDWKEVALDLNQSLIETQEKLQEANQEIADLKKIVAIYKEKEKEK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications