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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 24-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 6A-10
  • locus tag: HKM25_RS07910 [old locus tag: HKM25_1615 ]
  • pan locus tag?: PNEUPAN002967000
  • symbol: HKM25_RS07910
  • pan gene symbol?: —
  • synonym:
  • product: tyrosine-type recombinase/integrase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HKM25_RS07910 [old locus tag: HKM25_1615 ]
  • symbol: HKM25_RS07910
  • product: tyrosine-type recombinase/integrase
  • replicon: chromosome
  • strand: +
  • coordinates: 1544950..1546077
  • length: 1128
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP053210 (1544950..1546077) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGTGGATGGAAGAATTACCAAACGGCAAATATAAATTTTTTGAGCGATACAAAGATCCA
    TATACTGAGAAATTAAAAAAAGTTTCAGTAACCATGGAGAAGAAAACTCCCCAGGCAAGA
    AATCAAGCTGCTATCTTGTTGCAAGAGAAGATAAATAAAAAACTTAGCACAAAACAAGTA
    GAAAGCATTACATTTGAAGAAATCTATAACCTTTTTTATAAATCATGGGCGCAAACAGTA
    AAGGAATCAACAAAACATAATTGTAAATCAGTTGATAAGAAGATGAAGGAAGTCATACCA
    TCCGATACCATACTTGCTAATCTTGACAGGCGTTTTCTTCAAGAGGCTATTGAAAAAATT
    ATTGAAAGCAACGGATATATTACAGCTAAAAAAGTACGGCATAGGCTCAGAGGTATCTTT
    AATTACGCTGTTCAATACTCTTACATTGAAAACAACGAGGTCGATTATACTACGATTCCT
    CAAAAACCAAAGACTTTAGAAGAACTGGAAAAAAAGCGTAACAACTTTCTCACCATGCAA
    GAAATAAAAGCACTTGTCGATGTCCTTAATCGTCGAGAATATCACCAAAAGTACGCTGAT
    ATGGTTCTTGTGCTGACATTAACTGGTATGAGATATGGTGAGTTAACTGCCTTACAACTG
    AAGAATATAGACTTCGAAAACAACAAAATTGAGATCACAGGTAATTTTGATTCAGTAAAC
    AAAATCAAGACGCTACCAAAGACTACAAATTCAATACGGACAATCAAAGTATCAGAGAGT
    GTCATAGAAGCTATTCAAAGACAAATAGTACGACTTAGCGAACGTTTCCAGCCATTGTCA
    AGCGATGATTATATTTTCTGTTTTGAAAAATGGAATCAACCTACAACAATAGCTTGCTTC
    ATACAGATATTAAAAAAATATGGAAAACAGGCCAAAATAGAAAAAAACTTATCTAGCCAT
    ATTTTTAGGCATTCTCATATTTCGTTTTTAGCAGAGTCTGGCCTCCCAATAAAATCAATA
    ATGGATCGAGTTGGGCACTCAAATGCAAAAATGACTTTGGAAATCTATTCTCATACTACT
    GAAGATATGGAGGATAAACTGGTCAATAAATTAGATACTATTTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1128

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HKM25_RS07910 [old locus tag: HKM25_1615 ]
  • symbol: HKM25_RS07910
  • description: tyrosine-type recombinase/integrase
  • length: 375
  • theoretical pI: 9.79002
  • theoretical MW: 44025.6
  • GRAVY: -0.565867

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 72.6)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 61.1)
    and 2 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 56.2)
    Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 56.2)
  • TheSEED:
  • PFAM:
    DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 100.9)
    and 5 more
    NTP_transf (CL0260) Mab-21; Mab-21 protein nucleotidyltransferase domain (PF03281; HMM-score: 17.4)
    l-integrase_N (CL0469) Phage_int_SAM_5; Phage integrase SAM-like domain (PF13102; HMM-score: 17.3)
    no clan defined FlxA; FlxA-like protein (PF14282; HMM-score: 15.1)
    Anti-adapt_IraP; Sigma-S stabilisation anti-adaptor protein (PF10796; HMM-score: 13.6)
    AAA_lid (CL0671) AAA_lid_10; AAA lid domain (PF17872; HMM-score: 10.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9577
    • Cytoplasmic Membrane Score: 0.0051
    • Cell wall & surface Score: 0.0063
    • Extracellular Score: 0.0309
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003006
    • TAT(Tat/SPI): 0.0004
    • LIPO(Sec/SPII): 0.000444
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000266847 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAAILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSDTILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIPQKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTALQLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERFQPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESGLPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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