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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 28-AUG-2013

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TCH8431/19A
  • locus tag: HMPREF0837_10230 [new locus tag: HMPREF0837_RS01170 ]
  • pan locus tag?: PNEUPAN003922000
  • symbol: HMPREF0837_10230
  • pan gene symbol?: pcsB
  • synonym:
  • product: CHAP domain protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: HMPREF0837_10230 [new locus tag: HMPREF0837_RS01170 ]
  • symbol: HMPREF0837_10230
  • product: CHAP domain protein
  • replicon: chromosome
  • strand: -
  • coordinates: 220676..221854
  • length: 1179
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAGAAAAAAATCTTAGCGTCACTTTTATTAAGTACAGTAATGGTTTCTCAAGTAGCT
    GTTTTAACAACTGCGCATGCAGAAACGACTGATGACAAAATTGCTGCTCAAGATAATAAA
    ATTAGTAACTTAACAGCACAACAACAAGAAGCCCAAAAACAAGTTGATCAAATTCAGGAG
    CAAGTATCAGCTATTCAAGCTGAGCAGTCTAACTTGCAAGCTGAAAATGATAGATTACAA
    GCAGAATCTAAGAAACTCGAGGGTGAGATTACAGAACTTTCTAAGAACATTGTTTCTCGT
    AACCAATCGTTGGAAAAACAAGCTCGTAGTGCTCAAACAAATGGAGCCGTAACTAGCTAT
    ATCAATACCATTGTAAACTCAAAATCAATTACAGAAGCTATTTCACGTGTTGCTGCAATG
    AGTGAAATCGTATCTGCAAACAACAAAATGTTAGAACAACAAAAGGCAGATAAAAAAGCT
    ATTTCTGAAAAACAAGTAGCAAATAATGATGCTATCAATACTGTAATTGCTAATCAACAA
    AAATTGGCTGATGATGCTCAAGCATTGACTACGAAACAGGCAGAACTAAAAGCTGCTGAA
    TTAAGTCTTGCTGCTGAGAAAGCGACAGCTGAAGGGGAAAAAGCAAGTCTATTAGAGCAA
    AAAGCAGCAGCTGAGGCAGAGGCTCGTGCAGCTGCGGTAGCAGAAGCAGCTTATAAAGAA
    AAACGAGCTAGCCAACAACAATCAGTACTTGCTTCAGCAAACACTAACTTAACAGCTCAA
    GTGCAAGCAGTATCTGAATCTGCAGCAGCACCTGTCCGTGCAAAAGTTCGTCCAACATAC
    AGTACAAACGCTTCAAGTTATCCAATTGGAGAATGTACATGGGGAGTAAAAACATTGGCA
    CCTTGGGCTGGAGACTACTGGGGTAATGGAGCACAGTGGGCTACAAGTGCAGCAGCAGCA
    GGTTTCCGTACAGGTTCAACACCTCAAGTTGGAGCAATTGCATGTTGGAATGATGGTGGA
    TATGGTCACGTAGCGGTTGTTACAGCTGTTGAATCAACAACACGTATCCAAGTATCAGAA
    TCAAATTATGCAGGTAATCGTACAATTGGAAATCACCGTGGATGGTTCAATCCAACAACA
    ACTTCTGAAGGTTTTGTTACATATATTTATGCAGATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1179

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: HMPREF0837_10230 [new locus tag: HMPREF0837_RS01170 ]
  • symbol: HMPREF0837_10230
  • description: CHAP domain protein
  • length: 392
  • theoretical pI: 5.88611
  • theoretical MW: 41697
  • GRAVY: -0.401786

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02168; HMM-score: 21.2)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02168; HMM-score: 21.2)
    TIGR02594 family protein (TIGR02594; HMM-score: 17.7)
    and 5 more
    Cellular processes Cellular processes Cell division chromosome segregation protein SMC (TIGR02169; HMM-score: 16.6)
    Genetic information processing DNA metabolism Chromosome-associated proteins chromosome segregation protein SMC (TIGR02169; HMM-score: 16.6)
    helix-rich protein (TIGR04523; HMM-score: 7.4)
    Genetic information processing DNA metabolism DNA replication, recombination, and repair transcription-repair coupling factor (TIGR00580; EC 3.6.1.-; HMM-score: 4.9)
    Genetic information processing Mobile and extrachromosomal element functions Plasmid functions integrating conjugative element protein, PFL_4705 family (TIGR03752; HMM-score: 3.8)
  • TheSEED  :
    • Secreted antigen GbpB/SagA/PcsB, putative peptidoglycan hydrolase
  • PFAM:
    Peptidase_CA (CL0125) CHAP; CHAP domain (PF05257; HMM-score: 54.2)
    and 12 more
    no clan defined DUF3450; Protein of unknown function (DUF3450) (PF11932; HMM-score: 22.1)
    ATG16; Autophagy protein 16 (ATG16) (PF08614; HMM-score: 18.4)
    DUF2968; Protein of unknown function (DUF2968) (PF11180; HMM-score: 16)
    FtsL (CL0225) DivIC; Septum formation initiator (PF04977; HMM-score: 15.5)
    no clan defined Crescentin; Crescentin protein (PF19220; HMM-score: 13.6)
    TssO; Type VI secretion system, TssO (PF17561; HMM-score: 8.9)
    Sec34; Sec34-like family (PF04136; HMM-score: 8.7)
    APG6_N; Apg6 coiled-coil region (PF17675; HMM-score: 8.7)
    YabA; Initiation control protein YabA (PF06156; HMM-score: 8.6)
    FlaC_arch; Flagella accessory protein C (FlaC) (PF05377; HMM-score: 7.4)
    HALZ; Homeobox associated leucine zipper (PF02183; HMM-score: 6.9)
    Spc7; Spc7 kinetochore protein (PF08317; HMM-score: 6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helix: 1
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.0008
    • Cell wall & surface Score: 0.0069
    • Extracellular Score: 0.9923
  • SignalP: Signal peptide SP(Sec/SPI) length 27 aa
    • SP(Sec/SPI): 0.997761
    • TAT(Tat/SPI): 0.000454
    • LIPO(Sec/SPII): 0.001269
    • Cleavage Site: CS pos: 27-28. AHA-ET. Pr: 0.9804
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADI68458 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNLTAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQSLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKAISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLLEQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKVRPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIACWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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