PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 28-AUG-2013

⊟Summary

• organism: Streptococcus pneumoniae TCH8431/19A
• locus tag: HMPREF0837_11349 [new locus tag: HMPREF0837_RS06465 ]
• pan locus tag^?: PNEUPAN002289000
• symbol: HMPREF0837_11349
• pan gene symbol^?: —
• synonym:
• product: transposase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: HMPREF0837_11349 [new locus tag: HMPREF0837_RS06465 ]
• symbol: HMPREF0837_11349
• product: transposase
• replicon: chromosome
• strand: +
• coordinates: 1250989..1251837
• length: 849
• essential: unknown

⊟Accession numbers

• Location: CP001993 (1250989..1251837) NCBI
• BioCyc: see HMPREF0837_RS06465
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  
  ATGGAACAATTACATTTTATCACAAAATTACTAGACATTAAAGACCCAAACATCAAGATT
  CTAGATATCATCAATATGGATACACACAAGGAAATCATCGCCAAACTGGACTACGACGCC
  CCATCTTGCCCTGAGTTCGGAAACCAATTGAAGAAATATGACTTTCAAAAACCTTCTAAA
  ATTCCTTATCTTGAAACGACTGGTATGCCTACTAGAATTCTCCTTAGAAAGCGTCGATTC
  AAGTGCTATCACTGTTCAAAAATGATGGTCGCTGAAACTTCTATCGTCAAGAAGAATCAC
  CAAATCCCTCGTATCATCAACCAAAAGATTGCTCAAAAGTTAATTGAAAAGATTTCTATG
  ACTGATATTGCCCATCAGCTTTCCATCTCAACTTCAACTGTCATTCGAAAGCTCAATGAC
  TTCCACTTTAAACATGATTTTTCTTGTCTTCCTGAGATTATGTCTTGGGATGAGTATGCT
  TTTACAAAAGGAAAGATGAGCTTCATTGCGCAAGATTTTAACAATCTCAATATCATCACT
  GTTCTTAAGGGAAGAACACAAGCTGTCATCCGAAATCACTTTCTTAAATATGATAGAGCC
  GTCCGATGTCGCGTCAAAATCATTACTATGGATATGTTTAGTCCTTACTATGACTTAGCT
  AGACAACTTTTCCCATGTGCTAAAATCGTGTTGGATCGCTTTCACATTGTACAACATCTT
  AGCCGTGCTATGAGTCGTGTGCGTGTCCAAATCATGAATCAGTTTCATCGAAAATCCCAT
  GAATACAAGGCTATCAAGCGCTACTGGAAACTCATTCAACAGGATAGCCGTAAACTGAGT
  GATAAGTGA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  849
  

⊟Protein

⊟General

• locus tag: HMPREF0837_11349 [new locus tag: HMPREF0837_RS06465 ]
• symbol: HMPREF0837_11349
• description: transposase
• length: 282
• theoretical pI: 10.4223
• theoretical MW: 33539.4
• GRAVY: -0.384397

⊟Function

• TIGRFAM:
• TheSEED  :
  • Mobile element protein
• PFAM:
  RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 92.2)
  and 13 more
  HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 37.1)
  Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 35)
  HTH (CL0123) HTH_7; Helix-turn-helix domain of resolvase (PF02796; HMM-score: 15.9)
  HTH_AsnC-type; AsnC-type helix-turn-helix domain (PF13404; HMM-score: 15.4)
  C2H2-zf (CL0361) zf-C2HE; C2HE / C2H2 / C2HC zinc-binding finger (PF16278; HMM-score: 15.4)
  HTH (CL0123) HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 14.3)
  HTH_11; HTH domain (PF08279; HMM-score: 13.8)
  HTH_23; Homeodomain-like domain (PF13384; HMM-score: 13.8)
  HTH_Crp_2; Crp-like helix-turn-helix domain (PF13545; HMM-score: 12.9)
  HTH_40; Helix-turn-helix domain (PF14493; HMM-score: 12)
  Mga; Mga helix-turn-helix domain (PF05043; HMM-score: 11.4)
  l-integrase_N (CL0469) Phage_int_SAM_2; Phage integrase, N-terminal (PF12834; HMM-score: 11)
  no clan defined BLYB; Borrelia hemolysin accessory protein (PF05289; HMM-score: 8.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.8508
  • Cytoplasmic Membrane Score: 0.0049
  • Cell wall & surface Score: 0.017
  • Extracellular Score: 0.1274
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.021985
  • TAT(Tat/SPI): 0.000145
  • LIPO(Sec/SPII): 0.000436
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: ADI69577 NCBI
• UniProt:

⊟Protein sequence

• MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYDAPSCPEFGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQIPRIINQKIAQKLIEKISMTDIAHQLSISTSTVIRKLNDFHFKHDFSCLPEIMSWDEYAFTKGKMSFIAQDFNNLNIITVLKGRTQAVIRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Transcription

• transcription start site:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications